Dissecting the role of Translational Regulation in Tumorigenesis

Project Information

TRANSREG

Grant agreement ID: 759006

DOI

10.3030/759006

Project closed

EC signature date 7 May 2018

Start date 1 August 2018

End date 31 October 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 977 148,00

EU contribution

€ 1 977 148,00

Coordinated by

UNIVERSITAT ZURICH
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Exploring the pan-cancer landscape of posttranscriptional regulation

Author(s): Umesh Ghoshdastider , Ataman Sendoel
Published in: Cell Reports, 2023, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.113172

In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution

Author(s): Peter F. Renz, Umesh Ghoshdastider, Simona Baghai Sain, Fabiola Valdivia-Francia, Ameya Khandekar, Mark Ormiston, Martino Bernasconi, Clara Duré, Jonas A. Kretz, Minkyoung Lee, Katie Hyams, Merima Forny, Marcel Pohly, Xenia Ficht, Stephanie J. Ellis, Andreas E. Moor, Ataman Sendoel
Published in: Nature, Issue 632, 2024, Page(s) 419-428, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-07663-y

No country for old methods: New tools for studying microproteins

Author(s): Fabiola Valdivia-Francia, Ataman Sendoel
Published in: iScience, Issue 27, 2025, Page(s) 108972, ISSN 2589-0042
Publisher: Elsevier BV
DOI: 10.1016/j.isci.2024.108972

Some like it translated: small ORFs in the 5′UTR

Author(s): Peter F. Renz, Fabiola Valdivia-Francia, Ataman Sendoel
Published in: Experimental Cell Research, Issue 396/1, 2020, Page(s) 112229, ISSN 0014-4827
Publisher: Academic Press
DOI: 10.1016/j.yexcr.2020.112229

Monitoring the 5′UTR landscape reveals isoform switches to drive translational efficiencies in cancer

Author(s): Weber, Ramona; Ghoshdastider, Umesh; Spies, Daniel; Duré, Clara; Valdivia-Francia, Fabiola; Forny, Merima; Ormiston, Mark; Renz, Peter F; Taborsky, David; Yigit, Merve; Bernasconi, Martino; Yamahachi, Homare; Sendoel, Ataman
Published in: Oncogene, 24 (9), Issue 1, 2023, ISSN 0950-9232
Publisher: Nature Publishing Group
DOI: 10.1038/s41388-022-02578-2

Other (2)

The alternative initiation factor eIF2A regulates 40S subunit turnover in ribosome-associated quality control

Author(s): Merve Yigit, Ramona Weber, Umesh Ghoshdastider, Anupam Das, Kivanc Nesanir, Fabiola Valdivia-Francia, Katie Hyams, David Taborsky, Peter F. Renz, Mark Ormiston, Clara Duré, Homare Yamahachi, Marko Jovanovic, Ataman Sendoel
Published in: bioRxiv, 2026
Publisher: openRxiv
DOI: 10.1101/2025.05.22.655611

<i>In vivo</i> single-cell CRISPR screening for microproteins identifies a critical ribosomal component

Author(s): Fabiola Valdivia-Francia, Umesh Ghoshdastider, Peter F. Renz, Daniel Spies, Mark Ormiston, Katie Hyams, Chenke Shi, Clara Duré, Merve Yigit, David Taborsky, Ameya Khandekar, Ramona Weber, Homare Yamahachi, Stephanie J. Ellis, Ataman Sendoel
Published in: bioRxiv, 2026
Publisher: openRxiv
DOI: 10.1101/2025.03.17.643322