Advancing cell based therapies by supporting implant survival

Project Information

ENABLE

Grant agreement ID: 759425

DOI

10.3030/759425

Project closed

EC signature date 7 September 2017

Start date 1 January 2018

End date 30 June 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

UNIVERSITEIT TWENTE
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (20)

A Modular Platform for Cytocompatible Hydrogels with Tailored Mechanical Properties Based on Monolithic Matrices and Particulate Building Blocks

Author(s): Lea Andrée; Pascal Bertsch; Rong Wang; Malin Becker; Jeroen Leijten; Peter Fischer; Fang Yang; Sander C. G. Leeuwenburgh
Published in: ACS Biomacromolecules, 2023, ISSN 1526-4602
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.3c00177

Self-Oxygenation of Tissues Orchestrates Full-Thickness Vascularization of Living Implants

Author(s): Ali Farzin; Ali Farzin; Shabir Hassan; Liliana Moreira Teixeira; Melvin Gurian; João F. Crispim; Varun Manhas; Aurélie Carlier; Hojae Bae; Liesbet Geris; Iman Noshadi; Su Ryon Shin; Jeroen Leijten; Jeroen Leijten
Published in: VOLUME=31;ISSUE=42;ISSN=1616-301X;TITLE=Advanced Functional Materials, Issue 3, 2021, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202100850

Aqueous Two-Phase Enabled Low Viscosity 3D (LoV3D) Bioprinting of Living Matter

Author(s): Malin Becker; Melvin Gurian; Maik Schot; Jeroen Leijten
Published in: Advanced science, Issue 1, 2022, Page(s) 10(8):2204609, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202204609

Self-oxygenation of engineered living tissues orchestrates osteogenic commitment of mesenchymal stem cells

Author(s): Shabir Hassan, Ting Wang, Kun Shi, Yike Huang, Maria Elizabeth Urbina Lopez, Kaifeng Gan, Mo Chen, Niels Willemen, Haroon Kalam, Eder Luna-Ceron, Berivan Cecen, Gihan Daw Elbait, Jinghang Li, Luis Enrique Garcia-Rivera, Melvin Gurian, Mudassir Meraj Banday, Kisuk Yang, Myung Chul Lee, Weida Zhuang, Castro Johnbosco, Oju Jeon, Eben Alsberg, Jeroen Leijten*, and Su Ryon Shin*.
Published in: Biomaterials, 2023, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2023.122179

Scalable fabrication, compartmentalization and applications of living microtissues

Author(s): Maik Schot; Nuno Araújo-Gomes; Bas van Loo; Tom Kamperman; Jeroen Leijten
Published in: Bioactive Materials, Issue 1, 2022, ISSN 2452-199X
Publisher: KeAi Publishing Communications Ltd.
DOI: 10.1016/j.bioactmat.2022.04.005

Steering Stem Cell Fate within 3D Living Composite Tissues Using Stimuli‐Responsive Cell‐Adhesive Micromaterials

Author(s): Tom Kamperman; Niels G. A. Willemen; Cindy Kelder; Michelle Koerselman; Malin Becker; Luanda Lins; Castro Johnbosco; Marcel Karperien; Jeroen Leijten
Published in: Advance Science, Issue 1, 2022, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202205487

Ultrahigh-Throughput Production of Monodisperse and Multifunctional Janus Microparticles Using in-Air Microfluidics

Author(s): Tom Kamperman, Vasileios D. Trikalitis, Marcel Karperien, Claas Willem Visser, Jeroen Leijten
Published in: ACS Applied Materials & Interfaces, Issue 10/28, 2018, Page(s) 23433-23438, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.8b05227

Fibronectin and Collagen IV Microcontact Printing Improves Insulin Secretion by INS1E Cells

Author(s): Elahe Hadavi, Jeroen Leijten, Jenny Brinkmann, Pascal Jonkheijm, Marcel Karperien, Aart van Apeldoorn
Published in: Tissue Engineering Part C: Methods, Issue 24/11, 2018, Page(s) 628-636, ISSN 1937-3384
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2018.0151

On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials

Author(s): Tom Kamperman, Bas van Loo, Melvin Gurian, Sieger Henke, Marcel Karperien, Jeroen Leijten
Published in: Lab on a Chip, Issue 19/11, 2019, Page(s) 1977-1984, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9lc00054b

Interconnectable Dynamic Compression Bioreactors for Combinatorial Screening of Cell Mechanobiology in Three Dimensions

Author(s): Jungmok Seo, Jung-Youn Shin, Jeroen Leijten, Oju Jeon, Ayça Bal Öztürk, Jeroen Rouwkema, Yuancheng Li, Su Ryon Shin, Hadi Hajiali, Eben Alsberg, Ali Khademhosseini
Published in: ACS Applied Materials & Interfaces, Issue 10/16, 2018, Page(s) 13293-13303, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.7b17991

Single-Cell Microgels: Technology, Challenges, and Applications

Author(s): Tom Kamperman, Marcel Karperien, Séverine Le Gac, Jeroen Leijten
Published in: Trends in Biotechnology, Issue 36/8, 2018, Page(s) 850-865, ISSN 0167-7799
Publisher: Elsevier BV
DOI: 10.1016/j.tibtech.2018.03.001

Microwell Scaffolds Using Collagen-IV and Laminin-111 Lead to Improved Insulin Secretion of Human Islets

Author(s): Elahe Hadavi, Jeroen Leijten, Marten Engelse, Eelco de Koning, Pascal Jonkheijm, Marcel Karperien, Aart van Apeldoorn
Published in: Tissue Engineering Part C: Methods, Issue 25/2, 2019, Page(s) 71-81, ISSN 1937-3384
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2018.0336

3D Printed Cartilage‐Like Tissue Constructs with Spatially Controlled Mechanical Properties

Author(s): Bruna A. G. Melo, Yasamin A. Jodat, Shreya Mehrotra, Michelle A. Calabrese, Tom Kamperman, Biman B. Mandal, Maria H. A. Santana, Eben Alsberg, Jeroen Leijten, Su Ryon Shin
Published in: Advanced Functional Materials, Issue 29/51, 2019, Page(s) 1906330, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201906330

Engineering 3D parallelized microfluidic droplet generators with equal flow profiles by computational fluid dynamics and stereolithographic printing

Author(s): Tom Kamperman, Liliana Moreira Teixeira, Seyedeh Sarah Salehi, Greet Kerckhofs, Yann Guyot, Mike Geven, Liesbet Geris, Dirk Grijpma, Sebastien Blanquer, Jeroen Leijten
Published in: Lab on a Chip, Issue 20/3, 2020, Page(s) 490-495, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9lc00980a

Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs

Author(s): Tom Kamperman, Michelle Koerselman, Cindy Kelder, Jan Hendriks, João F. Crispim, Xandra de Peuter, Pieter J. Dijkstra, Marcel Karperien, Jeroen Leijten
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12390-4

Enzymatic outside-in cross-linking enables single-step microcapsule production for high-throughput three-dimensional cell microaggregate formation

Author(s): B. van Loo, S.S. Salehi, S. Henke, A. Shamloo, T. Kamperman, M. Karperien, J. Leijten
Published in: Materials Today Bio, Issue 6, 2020, Page(s) 100047, ISSN 2590-0064
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.mtbio.2020.100047

Enzyme-Mediated Alleviation of Peroxide Toxicity in Self-Oxygenating Biomaterials

Author(s): Niels G. A. Willemen; Shabir Hassan; Melvin Gurian; Maria Fernanda Jasso‐Salazar; Kai Fan; Haihang Wang; Malin Becker; Iris E. Allijn; Ayça Bal‐Öztürk; Jeroen Leijten; Su Ryon Shin
Published in: Advanced healthcare materials, 11(13):2102697. Wiley, Issue 1, 2022, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202102697

Mass production of lumenogenic human embryoid bodies and functional cardiospheres using in-air-generated microcapsules

Author(s): Bas van Loo, Simone A. ten Den, Nuno Araújo-Gomes, Vincent de Jong, Rebecca R. Snabel, Maik Schot, José M. Rivera-Arbeláez, Gert Jan C. Veenstra, Robert Passier, Tom Kamperman, and Jeroen Leijten
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-42297-0

Tethering Cells via Enzymatic Oxidative Crosslinking Enables Mechanotransduction in Non-Cell-Adhesive Materials.

Author(s): Tom Kamperman; Tom Kamperman; Sieger Henke; João F. Crispim; Niels G A Willemen; Pieter J. Dijkstra; Wooje Lee; Herman L. Offerhaus; Martin Peter Neubauer; Alexandra M. Smink; Paul de Vos; Bart J. de Haan; Marcel Karperien; Su Ryon Shin; Jeroen Leijten
Published in: Advanced Materials, Issue 2, 2021, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202102660

Scalable Production of Size-Controlled Cholangiocyte and Cholangiocarcinoma Organoids within Liver Extracellular Matrix-Containing Microcapsules

Author(s): Gilles S. van Tienderen, Jorke Willemse, Bas van Loo, Eline V. A. van Hengel,Jeroen de Jonge,Luc J. W. van der Laan, Jeroen Leijten, and Monique M. A. Verstegen
Published in: Cells, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11223657