Dissecting Quality Control Mechanisms of Mislocalized Proteins

Project Information

MisloQC

Grant agreement ID: 759427

DOI

10.3030/759427

Project closed

EC signature date 20 October 2017

Start date 1 March 2018

End date 28 February 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 497 750,00

EU contribution

€ 1 497 750,00

Coordinated by

INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Book chapters (3)

Building yeast libraries to dissect terminal degrons with fluorescent timers

Author(s): Ka-Yiu Edwin Kong; Christian Reinbold; Michael Knop; Anton Khmelinskii
Published in: Methods in Enzymology, Issue 1, 2023
Publisher: Academic Press
DOI: 10.1016/bs.mie.2023.02.012

Multiplexed protein stability (MPS) profiling of terminal degrons using fluorescent timer libraries in Saccharomyces cerevisiae

Author(s): Christian Reinbold, Ka-Yiu Edwin Kong, Ilia Kats, Anton Khmelinskii, Michael Knop
Published in: Methods In Enzymology, 2023
Publisher: Academic Press
DOI: 10.1016/bs.mie.2023.02.017

High-Throughput Analysis of Protein Turnover with Tandem Fluorescent Protein Timers

Author(s): Fung, J.J., Blöcher-Juárez, K., Khmelinskii, A.
Published in: The Unfolded Protein Response. Methods in Molecular Biology, 2022, ISBN 978-1-0716-1732-8
Publisher: Humana
DOI: 10.1007/978-1-0716-1732-8_6

Peer reviewed articles (4)

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins

Author(s): Verena Dederer, Anton Khmelinskii, Anna Gesine Huhn, Voytek Okreglak, Michael Knop, Marius K Lemberg
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.45506

Quality control of mislocalized and orphan proteins

Author(s): Kong KE, Coelho JPL, Feige MJ, Khmelinskii A.
Published in: Experimental cell research, 2021, ISSN 0014-4827
Publisher: Academic Press
DOI: 10.1016/j.yexcr.2021.112617

Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase

Author(s): Ka-Yiu Edwin Kong, Bernd Fischer, Matthias Meurer, Ilia Kats, Zhaoyan Li, Frank Rühle, Joseph D. Barry, Daniel Kirrmaier, Veronika Chevyreva, Bryan-Joseph San Luis, Michael Costanzo, Wolfgang Huber, Brenda J. Andrews, Charles Boone, Michael Knop, Anton Khmelinskii
Published in: Molecular Cell, 2021, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2021.04.018

Orphan quality control by an SCF ubiquitin ligase directed to pervasive C-degrons

Author(s): Ka-Yiu Edwin Kong, Susmitha Shankar, Frank Rühle, Anton Khmelinskii
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-44096-z

Non-peer reviewed articles (1)

(Photo)convert to pooled visual screening

Author(s): Elena Ivanova, Anton Khmelinskii
Published in: Molecular Systems Biology, Issue 16/6, 2020, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.20209640