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Dissecting Cross-Regulatory Interplays in Tumor-Associated Macrophages

Publicaciones

Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models

Autores: Filippo Birocchi, Melania Cusimano, Federico Rossari, Stefano Beretta, Paola M V Rancoita, Anna Ranghetti, Stefano Colombo, Barbara Costa, Peter Angel, Francesca Sanvito, Marcella Callea, Rossana Norata, Linda Chaabane, Tamara Canu, Antonello Spinelli, Marco Genua, Renato Ostuni, Ivan Merelli, Nadia Coltella, Luigi Naldini
Publicado en: Science Translational Medicine, 2022, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abl4106

Co-option of Neutrophil Fates by Tissue Environments

Autores: Iván Ballesteros, Andrea Rubio-Ponce, Marco Genua, Eleonora Lusito, Immanuel Kwok, Gabriel Fernández-Calvo, Tariq E. Khoyratty, Erinke van Grinsven, Sara González-Hernández, José Ángel Nicolás-Ávila, Tommaso Vicanolo, Antonio Maccataio, Alberto Benguría, Jackson LiangYao Li, José M. Adrover, Alejandra Aroca-Crevillen, Juan A. Quintana, Sandra Martín-Salamanca, Francisco Mayo, Stefanie A
Publicado en: Cell, 2020, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2020.10.003

Determinants, mechanisms, and functional outcomes of myeloid cell diversity in cancer

Autores: Nicoletta Caronni, Elisa Montaldo, Luca Mezzanzanica, Francesco Cilenti, Marco Genua, Renato Ostuni
Publicado en: Immunological Reviews, Edición 300/1, 2021, Página(s) 220-236, ISSN 0105-2896
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imr.12944

A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression

Autores: Cilenti F, Barbiera G, Caronni N, Iodice D, Montaldo E, Barresi S, Lusito E, Cuzzola V, Vittoria FM, Mezzanzanica L, Miotto P, Di Lucia P, Lazarevic D, Cirillo DM, Iannacone M, Genua M, Ostuni R.
Publicado en: Immunity, Edición 10747613, 2021, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2021.05.016

Charting granulopoietic disturbances in sepsis

Autores: Roza Maria Barouni, Renato Ostuni
Publicado en: Nature Immunology, 2023, ISSN 1529-2916
Editor: Nature Publishing Group
DOI: 10.1038/s41590-023-01495-0

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

Autores: Alexandre P. Bénéchet, Giorgia De Simone, Pietro Di Lucia, Francesco Cilenti, Giulia Barbiera, Nina Le Bert, Valeria Fumagalli, Eleonora Lusito, Federica Moalli, Valentina Bianchessi, Francesco Andreata, Paola Zordan, Elisa Bono, Leonardo Giustini, Weldy V. Bonilla, Camille Bleriot, Kamini Kunasegaran, Gloria Gonzalez-Aseguinolaza, Daniel D. Pinschewer, Patrick T. F. Kennedy, Luigi Naldini, Mire
Publicado en: Nature, Edición 574/7777, 2019, Página(s) 200-205, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-019-1620-6

Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens

Autores: Giulia Escobar, Luigi Barbarossa, Giulia Barbiera, Margherita Norelli, Marco Genua, Anna Ranghetti, Tiziana Plati, Barbara Camisa, Chiara Brombin, Davide Cittaro, Andrea Annoni, Attilio Bondanza, Renato Ostuni, Bernhard Gentner, Luigi Naldini
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-05315-0

Adaptation and memory in immune responses

Autores: Gioacchino Natoli, Renato Ostuni
Publicado en: Nature Immunology, Edición 20/7, 2019, Página(s) 783-792, ISSN 1529-2908
Editor: Nature Publishing Group
DOI: 10.1038/s41590-019-0399-9

Heterogeneity of neutrophils

Autores: Lai Guan Ng, Renato Ostuni, Andrés Hidalgo
Publicado en: Nature Reviews Immunology, Edición 19/4, 2019, Página(s) 255-265, ISSN 1474-1733
Editor: Nature Publishing Group
DOI: 10.1038/s41577-019-0141-8

IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer

Autores: Nicoletta Caronni, Federica La Terza, Francesco M Vittoria, Giulia Barbiera, Luca Mezzanzanica, Vincenzo Cuzzola, Simona Barresi, Marta Pellegatta, Paolo Canevazzi, Garett Dunsmore, Carlo Leonardi, Elisa Montaldo, Eleonora Lusito, Erica Dugnani, Antonio Citro, Melissa S F Ng, Marco Schiavo Lena, Denise Drago, Annapaola Andolfo, Silvia Brugiapaglia, Alessandro Scagliotti, Alessandra Mortellaro, Vin
Publicado en: Nature, 2023, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-023-06685-2

Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress

Autores: Elisa Montaldo, Eleonora Lusito, Valentina Bianchessi, Nicoletta Caronni, Serena Scala, Luca Basso-Ricci, Carla Cantaffa, Alice Masserdotti, Mattia Barilaro, Simona Barresi, Marco Genua, Francesco Maria Vittoria, Giulia Barbiera, Dejan Lazarevic, Carlo Messina, Elisabetta Xue, Sarah Marktel, Cristina Tresoldi, Raffaella Milani, Paola Ronchi, Salvatore Gattillo, Luca Santoleri, Raffaella Di Micco,
Publicado en: Nature Immunology, Edición 15292908, 2022, ISSN 1529-2908
Editor: Nature Publishing Group
DOI: 10.1038/s41590-022-01311-1

Drugging inflammation: Easier NSAID than done

Autores: Nicoletta Caronni, Renato Ostuni
Publicado en: Immunity, Edición 10747613, 2022, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2022.05.009

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