Rational combination therapies for metastatic cancer

Project Information

CombaTCancer

Grant agreement ID: 759590

DOI

10.3030/759590

Project closed

EC signature date 12 December 2017

Start date 1 March 2018

End date 31 May 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Allies or Enemies—The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment

Author(s): Lisa Haas, Anna C. Obenauf
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2019.02746

Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters

Author(s): Christian Umkehrer, Felix Holstein, Laura Formenti, Julian Jude, Kimon Froussios, Tobias Neumann, Shona M. Cronin, Lisa Haas, Jesse J. Lipp, Thomas R. Burkard, Michaela Fellner, Thomas Wiesner, Johannes Zuber, Anna C. Obenauf
Published in: Nature Biotechnology, 2020, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/s41587-020-0614-0

Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma

Author(s): Lisa Haas, Anais Elewaut, Camille L. Gerard, Christian Umkehrer, Lukas Leiendecker, Malin Pedersen, Izabela Krecioch, David Hoffmann, Maria Novatchkova, Mario Kuttke, Tobias Neumann, Ines Pires da Silva, Harriet Witthock, Michel A. Cuendet, Sebastian Carotta, Kevin J. Harrington, Johannes Zuber, Richard A. Scolyer, Georgina V. Long, James S. Wilmott, Olivier Michielin, Sakari Vanharanta, Thomas Wi
Published in: Nature Cancer, Issue 2, 2022, Page(s) 693-708, ISSN 2662-1347
Publisher: Springer Nature
DOI: 10.1038/s43018-021-00221-9

LSD1 inhibitors induce neuronal differentiation of Merkel cell carcinoma by disrupting the LSD1-CoREST complex and activating TGFβ signaling

Author(s): Lukas Leiendecker; Pauline S. Jung; Tobias Neumann; Thomas Wiesner; Anna C. Obenauf
Published in: EMBO Molecular Medicine, Issue 1, 2020, ISSN 1757-4684
Publisher: EMBO press
DOI: 10.1101/2020.04.14.041657

Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers

Author(s): Lukas Leiendecker, Tobias Neumann, Pauline S. Jung, Shona M. Cronin, Thomas L. Steinacker, Alexander Schleiffer, Michael Schutzbier, Karl Mechtler, Thibault Kervarrec, Estelle Laurent, Kamel Bachiri, Etienne Coyaud, Rajmohan Murali, Klaus J. Busam, Babak Itzinger-Monshi, Reinhard Kirnbauer, Lorenzo Cerroni, Eduardo Calonje, Arno Rütten, Frank Stubenrauch, Klaus G. Griewank, Thomas Wiesner, Anna C
Published in: Cancer Discovery, Issue 13, 2023, Page(s) 70-84, ISSN 2159-8274
Publisher: American Association for Cancer Research Inc.
DOI: 10.1158/2159-8290.cd-22-0489

Non-peer reviewed articles (1)

Mechanism-based combination therapies for metastatic cancer

Author(s): Anna C. Obenauf
Published in: Science Translational Medicine, Issue 14, 2024, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.add0887