Fatty acid incorporation and modification in cyanobacterial natural products

Project Information

FattyCyanos

Grant agreement ID: 759840

DOI

10.3030/759840

Project closed

EC signature date 2 October 2017

Start date 1 January 2018

End date 31 December 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 462 938,00

EU contribution

€ 1 462 938,00

Coordinated by

CENTRO INTERDISCIPLINAR DE INVESTIGACAO MARINHA E AMBIENTAL
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Fatty acyl-AMP ligases in bacterial natural product biosynthesis

Author(s): Anne Liong, Pedro N. Leão
Published in: Natural Product Reports, 2025, ISSN 0265-0568
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4np00073k

Incorporation, fate, and turnover of free fatty acids in cyanobacteria

Author(s): Amaranta Kahn; Paulo Oliveira; Marine Cuau; Pedro N Leão
Published in: FEMS Microbiology Reviews, Issue 5, 2023, ISSN 0168-6445
Publisher: Blackwell
DOI: 10.1093/femsre/fuad015

Incorporation and modification of fatty acids in cyanobacterial natural products biosynthesis

Author(s): Pedro N. Leão; Teresa P. Martins; Kathleen Abt; João P. A. Reis; Sandra Figueiredo; Raquel Castelo-Branco; Sara Freitas
Published in: Chemical Communications, Issue 4, 2023, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3cc00136a

Isolation and Biosynthesis of Hyellamide, a Glycosylated N-Acyltyrosine Derivative, from the Cyanobacterium <i>Hyella patelloides</i> LEGE 07179

Author(s): Ângela Brito, Teresa Martins, Sara Freitas, Raquel Castelo Branco, Adriana Rego, Vitor M. Vasconcelos, William H. Gerwick, Paula Tamagnini, Pedro N. Leão
Published in: Journal of Natural Products, Issue 88, 2025, Page(s) 850-856, ISSN 0163-3864
Publisher: American Chemical Society
DOI: 10.1021/acs.jnatprod.4c00968

Chemistry, bioactivity and biosynthesis of cyanobacterial alkylresorcinols

Author(s): Teresa P. Martins, Caroline Rouger, Nathaniel R. Glasser, Sara Freitas, Nelly B. de Fraissinette, Emily P. Balskus, Deniz Tasdemir, Pedro N. Leão
Published in: Natural Product Reports, Issue Awaits publication in print (online only for now), 2019, ISSN 0265-0568
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8np00080h

BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters

Author(s): João P. A. Reis, Sandra A. C. Figueiredo, Maria Lígia Sousa, Pedro N. Leão
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-15302-z

Biosynthesis of the Unusual Carbon Skeleton of Nocuolin A

Author(s): Martins, Teresa P.; Glasser, Nathaniel R.; Kountz, Duncan J.; Oliveira, Paulo; Balskus, Emily P.; Leão, Pedro N.
Published in: ACS Chemical Biology, Issue 3, 2022, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.2c00464

Discovery of Cyanobacterial Natural Products Containing Fatty Acid Residues

Author(s): Sandra A.C. Figueiredo; Marco Preto; Gabriela Moreira; Teresa P. Martins; Kathleen Abt; André Melo; Vitor Vasconcelos; Pedro N. Leão
Published in: Angewandte Chemie (International Ed. in English), Issue 1, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202015105

Biosynthesis of Chlorinated Lactylates in Sphaerospermopsis sp. LEGE 00249.

Author(s): Kathleen Abt; Raquel Castelo-Branco; Pedro N. Leão
Published in: Journal of Natural Products, Issue 1, 2021, ISSN 0163-3864
Publisher: American Chemical Society
DOI: 10.26434/chemrxiv.12885476.v2

Thesis and dissertations (5)

A novel biocatalytic esterification involved in the biosynthesis of branched bartolosides

Author(s): João Pedro Alves Rodrigues dos Reis
Published in: reponame:Repositório Científico de Acesso Aberto de Portugal, Issue 1, 2019
Publisher: University of Porto

Pathway discovery and ecophysiological relevance of a new enzyme and its products involved in exogenous fatty acid incorporation in cyanobacteria

Author(s): Ricardo Júnio Coelho Vitorino de Queirós
Published in: reponame:Repositório Científico de Acesso Aberto de Portugal, 2022
Publisher: Universidade do Porto

Exploiting cyanobacterial metabolism to unveil new natural products and inquire about beta-oxidation

Author(s): Bárbara Rêgo Pires
Published in: reponame:Repositório Científico de Acesso Aberto de Portugal, 2022
Publisher: repositorio aberto Universidade do Porto

Descoberta de novos produtos naturais de cianobactérias com bioatividade

Author(s): Moreira, Gabriela Alves
Published in: Issue 1, 2021
Publisher: Universidade do Minho

Biosynthesis of nocuolin A and related metabolites

Author(s): Teresa Patrícia Pedrosa Martins
Published in: reponame:Repositório Científico de Acesso Aberto de Portugal, 2024
Publisher: repositorio aberto Universidade do Porto

Other (2)

Biosynthesis of the unusual carbon skeleton of nocuolin A

Author(s): Teresa Martins; Nathaniel Glasser; Duncan Kountz; Paulo Oliveira; Emily Balskus; Pedro Leão
Published in: ChemRxiv, Issue 1, 2022
Publisher: ChemRxiv
DOI: 10.26434/chemrxiv-2022-jv5n7

Fischerazoles A-C, cyanobacterial polychlorinated lipids featuring fatty acyl chain rearrangement

Author(s): Sandra Figueiredo; Kathleen Abt; Teresa Martins; Iñaki Lacomba; Abel Forero; Carlos Jiménez; Jaime Rodríguez; Pedro Leão
Published in: ChemRxiv, Issue 1, 2022
Publisher: ChemRxiv
DOI: 10.26434/chemrxiv-2022-v8zlp