Fatty acid incorporation and modification in cyanobacterial natural products

Project Information

FattyCyanos

Grant agreement ID: 759840

DOI 10.3030/759840

Project closed

EC signature date 2 October 2017

Start date 1 January 2018

End date 31 December 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 462 938,00

EU contribution € 1 462 938,00

Coordinated by

CENTRO INTERDISCIPLINAR DE INVESTIGACAO MARINHA E AMBIENTAL
Portugal

Publications

Peer reviewed articles (7)

Incorporation, fate, and turnover of free fatty acids in cyanobacteria

Author(s): Amaranta Kahn; Paulo Oliveira; Marine Cuau; Pedro N Leão
Published in: FEMS Microbiology Reviews, Issue 5, 2023, ISSN 0168-6445
Publisher: Blackwell
DOI: 10.1093/femsre/fuad015

Incorporation and modification of fatty acids in cyanobacterial natural products biosynthesis

Author(s): Pedro N. Leão; Teresa P. Martins; Kathleen Abt; João P. A. Reis; Sandra Figueiredo; Raquel Castelo-Branco; Sara Freitas
Published in: Chemical Communications, Issue 4, 2023, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3cc00136a

Chemistry, bioactivity and biosynthesis of cyanobacterial alkylresorcinols

Author(s): Teresa P. Martins, Caroline Rouger, Nathaniel R. Glasser, Sara Freitas, Nelly B. de Fraissinette, Emily P. Balskus, Deniz Tasdemir, Pedro N. Leão
Published in: Natural Product Reports, Issue Awaits publication in print (online only for now), 2019, ISSN 0265-0568
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8np00080h

BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters

Author(s): João P. A. Reis, Sandra A. C. Figueiredo, Maria Lígia Sousa, Pedro N. Leão
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-15302-z

Biosynthesis of the Unusual Carbon Skeleton of Nocuolin A

Author(s): Martins, Teresa P.; Glasser, Nathaniel R.; Kountz, Duncan J.; Oliveira, Paulo; Balskus, Emily P.; Leão, Pedro N.
Published in: ACS Chemical Biology, Issue 3, 2022, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.2c00464

Discovery of Cyanobacterial Natural Products Containing Fatty Acid Residues

Author(s): Sandra A.C. Figueiredo; Marco Preto; Gabriela Moreira; Teresa P. Martins; Kathleen Abt; André Melo; Vitor Vasconcelos; Pedro N. Leão
Published in: Angewandte Chemie (International Ed. in English), Issue 1, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202015105

Biosynthesis of Chlorinated Lactylates in Sphaerospermopsis sp. LEGE 00249.

Author(s): Kathleen Abt; Raquel Castelo-Branco; Pedro N. Leão
Published in: Journal of Natural Products, Issue 1, 2021, ISSN 0163-3864
Publisher: American Chemical Society
DOI: 10.26434/chemrxiv.12885476.v2

Thesis and dissertations (3)

A novel biocatalytic esterification involved in the biosynthesis of branched bartolosides

Author(s): João Pedro Alves Rodrigues dos Reis
Published in: Issue 1, 2019
Publisher: Univrersity of Porto

A novel biocatalytic esterification involved in the biosynthesis of branched bartolosides

Author(s): João Pedro Alves Rodrigues dos Reis
Published in: reponame:Repositório Científico de Acesso Aberto de Portugal, Issue 1, 2019
Publisher: University of Porto

Descoberta de novos produtos naturais de cianobactérias com bioatividade

Author(s): Moreira, Gabriela Alves
Published in: Issue 1, 2021
Publisher: Universidade do Minho

Other (2)

Biosynthesis of the unusual carbon skeleton of nocuolin A

Author(s): Teresa Martins; Nathaniel Glasser; Duncan Kountz; Paulo Oliveira; Emily Balskus; Pedro Leão
Published in: ChemRxiv, Issue 1, 2022
Publisher: ChemRxiv
DOI: 10.26434/chemrxiv-2022-jv5n7

Fischerazoles A-C, cyanobacterial polychlorinated lipids featuring fatty acyl chain rearrangement

Author(s): Sandra Figueiredo; Kathleen Abt; Teresa Martins; Iñaki Lacomba; Abel Forero; Carlos Jiménez; Jaime Rodríguez; Pedro Leão
Published in: ChemRxiv, Issue 1, 2022
Publisher: ChemRxiv
DOI: 10.26434/chemrxiv-2022-v8zlp