SENSING CELL-CELL INTERACTION HETEROGENEITY IN 3D TUMOR MODELS: TOWARDS PRECISION MEDICINE

Electrospun nanofibers in cancer research: from engineering of in vitro 3D cancer models to therapy

Author(s): Marta Cavo, Francesca Serio, Narendra R. Kale, Eliana D'Amone, Giuseppe Gigli, Loretta L. del Mercato
Published in: Biomaterials Science, Issue 8/18, 2020, Page(s) 4887-4905, ISSN 2047-4830
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0bm00390e

The Revolutionary Roads to Study Cell–Cell Interactions in 3D In Vitro Pancreatic Cancer Models

Author(s): Donatella Delle Cave; Riccardo Rizzo; Bruno Sainz; Giuseppe Gigli; Giuseppe Gigli; Loretta L. del Mercato; Enza Lonardo
Published in: Cancers, Issue 2, 2021, Page(s) 13(4), 930, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13040930

NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery

Author(s): Norma Depalma, Stefano D'Ugo, Farshad Manoochehri, Annarita Libia, William Sergi, Tiziana R L Marchese, Stefania Forciniti, Loretta L Del Mercato, Prisco Piscitelli, Stefano Garritano, Fabio Castellana, Roberta Zupo, Marcello Giuseppe Spampinato
Published in: Cancers, Issue https://doi.org/10.3390/cancers15235528, 2023, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15235528

Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery

Author(s): Francesca Serio, Anderson Fragada Cruz, Anil Chandra, Concetta Nobile, Gustavo Rodrigues Rossi, Eliana D'Amone, Giuseppe Gigli, Loretta Laureana del Mercato, Carolina Camargo de Oliveira
Published in: International Journal of Biological Macromolecules, 2021, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/j.ijbiomac.2021.08.069

Probing Single-Cell Fermentation Fluxes and Exchange Networks via pH-Sensing Hybrid Nanofibers

Author(s): Valentina Onesto, Stefania Forciniti, Francesco Alemanno, Krishnadev Narayanankutty, Anil Chandra, Saumya Prasad, Amalia Azzariti, Giuseppe Gigli, Adriano Barra, Andrea De Martino, Daniele De Martino, and Loretta L. del Mercato
Published in: ACS Nano, 2023, Page(s) 17, 4, 3313–3323, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.2c06114

Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications

Author(s): Giuliana Grasso; Francesco Colella; Stefania Forciniti; Valentina Onesto; Helena Iuele; Anna Chiara Siciliano; Federica Carnevali; Anil Chandra; Giuseppe Gigli; Loretta L. del Mercato
Published in: Nanoscale Advances, Issue 5, 2023, Page(s) 5, 4311-4336, ISSN 2516-0230
Publisher: RSC
DOI: 10.1039/d3na00218g

pH-Sensing Hybrid Hydrogels for Non-Invasive Metabolism Monitoring in Tumor Spheroids

Author(s): Riccardo Rizzo, Valentina Onesto, Giulia Morello, Helena Iuele, Francesca Scalera, Stefania Forciniti, Giuseppe Gigli, Alessandro Polini, Francesca Gervaso, Loretta L. del Mercato
Published in: Materials Today Bio, 2023, Page(s) 20, 100655, ISSN 1369-7021
Publisher: Elsevier BV
DOI: 10.1016/j.mtbio.2023.100655

Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

Author(s): Prasad, Saumya; Chandra, Anil; Cavo, Marta; Parasido, Erika; Fricke, Stanley; Lee, Yichien; D'Amone, Eliana; Gigli, Giuseppe; Albanese, Chris; Rodriguez, Olga; del Mercato, Loretta L.
Published in: Nanotechnology, 2021, Page(s) 36, ISSN 0957-4484
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6528/abc208

Quantifying heterogeneity to drug response in cancer–stroma kinetics

Author(s): Francesco Alemanno; Marta Cavo; Donatella Delle Cave; Alberto Fachechi; Riccardo Rizzo; Eliana D’Amone; Giuseppe Gigli; Enza Lonardo; Adriano Barra; Loretta L. del Mercato
Published in: Proceedings of the National Academy of Sciences (PNAS), Issue 2, 2023, Page(s) 120 (11) e2122352120, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2122352120

Co-loading of Doxorubicin and Iron Oxide Nanocubes in Polycaprolactone Fibers for Combining Magneto-Thermal and Chemotherapeutic Effects on Cancer Cells

Author(s): Francesca Serio, Niccolò Silvestri, Sahitya Kumar Avugadda, Giulia E.P. Nucci, Simone Nitti, Valentina Onesto, Federico Catalano, Eliana D'Amone, Giuseppe Gigli, Loretta L. del Mercato, Teresa Pellegrino
Published in: Journal of Colloid and Interface Science, 2022, ISSN 0021-9797
Publisher: Academic Press
DOI: 10.1016/j.jcis.2021.08.153

Preparation and Investigation of Thermally Annealed Zein–Propolis Electrospun Nanofibers for Biomedical Applications

Author(s): Hochheim, S., Sampaio, N. M. F. M., da Cruz, A. F., del Mercato, L. L., D’Amone, E., da Silva, B. J. G., Saul, C. K., de Oliveira, C. C., Riegel-Vidotti, I.
Published in: Macromolecular Bioscience, 2023, Page(s) 2200524, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202200524

Towards the development of human immune-system-on-a-chip platforms

Author(s): Alessandro Polini, Loretta L. del Mercato, Adriano Barra, Yu Shrike Zhang, Franco Calabi, Giuseppe Gigli
Published in: Drug Discovery Today, 2018, ISSN 1359-6446
Publisher: Elsevier BV
DOI: 10.1016/j.drudis.2018.10.003

Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models

Author(s): Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli, Loretta L. del Mercato
Published in: Current Medicinal Chemistry, Issue 25/35, 2018, Page(s) 4616-4637, ISSN 0929-8673
Publisher: Bentham Science Publishers
DOI: 10.2174/0929867325666180605122633

Highly Sensitive Ratiometric Fluorescent Fiber Matrixes for Oxygen Sensing with Micrometer-Spatial Resolution

Author(s): Grasso G., Onesto V., Forciniti S., D’Amone E., Colella F., Pierantoni L., Famà V., Gigli G., Reis R.L., Oliveira J.M., del Mercato L.L.
Published in: Bio-Design and Manufacturing, 2024, ISSN 2096-5524
Publisher: Springer Nature
DOI: 10.1007/s42242-024-00277-3

A 3D Pancreatic Cancer Model with Integrated Optical Sensors for Noninvasive Metabolism Monitoring and Drug Screening

Author(s): Anna Chiara Siciliano, Stefania Forciniti, Valentina Onesto, Helena Iuele, Donatella Delle Cave, Federica Carnevali, Giuseppe Gigli, Enza Lonardo, Loretta L. del Mercato
Published in: Advanced Healthcare Materials, 2024, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202401138

A pH-sensor scaffold for mapping spatiotemporal gradients in three-dimensional in vitro tumour models

Author(s): Riccardo Rizzo, Valentina Onesto, Stefania Forciniti, Anil Chandra, Saumya Prasad, Helena Iuele, Francesco Colella, Giuseppe Gigli, Loretta L. del Mercato
Published in: Biosensors and Bioelectronics, 2022, ISSN 0956-5663
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2022.114401

A synergic approach to enhance long-term culture and manipulation of MiaPaCa-2 pancreatic cancer spheroids

Author(s): Marta Cavo, Donatella Delle Cave, Eliana D’Amone, Giuseppe Gigli, Enza Lonardo, Loretta L. del Mercato
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-66908-8

Beyond gold nanoparticles cytotoxicity: Potential to impair metastasis hallmarks

Author(s): Jenifer Pendiuk Gonçalves, Anderson Fraga da Cruz, Heloise Ribeiro de Barros, Beatriz Santana Borges, Lia Carolina Almeida Soares de Medeiros, Maurilio José Soares, Mayara Padovan dos Santos, Marco Tadeu Grassi, Anil Chandra, Loretta Laureana del Mercato, Gustavo Rodrigues Rossi, Edvaldo da Silva Trindade, Izabel Cristina Riegel-Vidotti, Carolina Camargo de Oliveira
Published in: European Journal of Pharmaceutics and Biopharmaceutics, 2020, Page(s) 221-232, ISSN 0939-6411
Publisher: Elsevier BV
DOI: 10.1016/j.ejpb.2020.10.019

Highly sensitive fluorescent pH microsensor based on the ratiometric dye pyranine immobilized on silica microparticles

Author(s): Anil Chandra, Saumya Prasad, Helena Iuele, Francesco Colella, Riccardo Rizzo, Eliana D'Amone, Giuseppe Gigli, Loretta L. del Mercato
Published in: Chemistry—A European Journal, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202101568

Probing the pH Microenvironment of Mesenchymal Stromal Cell Cultures on Additive‐Manufactured Scaffolds

Author(s): Ivan Lorenzo Moldero, Anil Chandra, Marta Cavo, Carlos Mota, Dimitrios Kapsokalyvas, Giuseppe Gigli, Lorenzo Moroni, Loretta L. Mercato
Published in: Small, Issue 16/34, 2020, Page(s) 2002258, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202002258

Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors

Author(s): Anil Chandra, Saumya Prasad, Francesco Alemanno, Maria De Luca, Riccardo Rizzo, Roberta Romano, Giuseppe Gigli, Cecilia Bucci, Adriano Barra, and Loretta L. del Mercato
Published in: ACS Applied Materials & Interfaces, 2022, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.2c00389

Inside front cover

Author(s): Marta Cavo; Francesca Serio; Narendra R. Kale; Eliana D'Amone; Giuseppe Gigli; Loretta L. del Mercato
Published in: Biomaterials Science, 2020
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0bm90078h

Cover: Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors

Author(s): Anil Chandra, Saumya Prasad, Francesco Alemanno, Maria De Luca, Riccardo Rizzo, Roberta Romano, Giuseppe Gigli, Cecilia Bucci, Adriano Barra, and Loretta L. del Mercato
Published in: 2022
Publisher: ACS

Front Cover Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications

Author(s): Giuliana Grasso; Francesco Colella; Stefania Forciniti; Valentina Onesto; Helena Iuele; Anna Chiara Siciliano; Federica Carnevali; Anil Chandra; Giuseppe Gigli; Loretta L. del Mercato
Published in: Nanoscale Advances, 2023, Page(s) Volume 5, Number 17, 7 September 2023, Pages 4301–4612
Publisher: RSC

Cover Profile: Highly sensitive fluorescent pH microsensor based on the ratiometric dye pyranine immobilized on silica microparticles (2021)

Author(s): Anil Chandra, Saumya Prasad, Helena Iuele, Francesco Colella, Riccardo Rizzo, Eliana D'Amone, Giuseppe Gigli, Loretta L. del Mercato
Published in: Chemistry – A European Journal, 2021, Page(s) 27, 13279
Publisher: WILEY
DOI: 10.1002/chem.202102674

Front Cover: Probing single cell fermentation fluxes and exchange networks via pH-sensing hybrid nanofibers

Author(s): Valentina Onesto, Stefania Forciniti, Francesco Alemanno, Krishnadev Narayanankutty, Anil Chandra, Saumya Prasad, Amalia Azzariti, Giuseppe Gigli, Adriano Barra, Andrea De Martino, Daniele De Martino, and Loretta L. del Mercato
Published in: ACS Nano, 2023, Page(s) February 28, 2023 Volume 17, Issue 4 Pages 3205-4090
Publisher: ACS

pH Monitoring: Probing the pH Microenvironment of Mesenchymal Stromal Cell Cultures on Additive‐Manufactured Scaffolds (Small 34/2020)

Author(s): Ivan Lorenzo Moldero; Anil Chandra; Marta Cavo; Carlos Mota; Dimitrios Kapsokalyvas; Giuseppe Gigli; Giuseppe Gigli; Lorenzo Moroni; Lorenzo Moroni; Loretta L. del Mercato
Published in: Small, Issue 4, 2020
Publisher: SMALL
DOI: 10.1002/smll.202070187

Abstract A48: Quantifying stroma-tumor cell interactions in three-dimensional cell culture systems

Author(s): Marta Maria Cavo; Francesco Alemanno; Donatella Delle Cave; Eliana D'Amone; Adriano Barra; Enza Lonardo; Erika Parasido; Chris Albanese; Loretta Laureana del Mercato
Published in: Poster Presentations - Proffered Abstracts, Issue June 1 2020 (80) (11 Supplement) A48;, 2020, Page(s) (2020) 80 (11_Supplement): A48., ISBN 979-8-9857852-5-8
Publisher: Cancer Research
DOI: 10.1158/1538-7445.camodels2020-a48

Abstract 1577: Gene expression studies using microgel embedded pancreatic cancer spheroids

Author(s): Saumya Prasad; Anil Chandra; Enza Lonardo; Erika Parasido; Christopher Albanese; Loretta L. del Mercato
Published in: Poster Presentations - Proffered Abstracts, Issue 1, 2020, Page(s) 80 (16_Supplement): 1577., ISBN 979-8-9857852-5-8
Publisher: Cancer Reseacrh
DOI: 10.1158/1538-7445.am2020-1577

Abstract 2967: Microgel-based in vitro tumoroid platform for real time assessment of drug sensitivity and resistance

Author(s): Anil Chandra; Saumya Prasad; Francesco Alemanno; Adriano Barra; Enza Lonardo; Erika Parasido; Christopher Albanese; Loretta L. del Mercato
Published in: Poster Presentations - Proffered Abstracts, Issue 2, 2020, Page(s) 80 (16_Supplement): 2967, ISBN 979-8-9857852-5-8
Publisher: Cancer Research
DOI: 10.1158/1538-7445.am2020-2967

Multilayer polyelectrolyte capsules for sensing and drug delivery: Fundamentals and applications

Author(s): del Mercato L.L., Leporatti S., Ferraro M.M., Hanafy N.A., Rinaldi R., Parak W.J., Carregal-Romero S.
Published in: Bio-Nano Interfaces: Perspectives, Properties, and Applications, 2024, Page(s) Chapter 57, ISBN 9789814877435
Publisher: Jenny Stanford Publishing
DOI: 10.1201/9781003306498

Fluorescent nanoparticles for sensing

Author(s): Anil Chandra, Saumya Prasad, Giuseppe Gigli, Loretta L. del Mercato
Published in: Colloids for Nanobiotechnology - Synthesis, Characterization and Potential Applications, Issue 16, 2020, Page(s) 117-149, ISBN 9780-081028285
Publisher: Elsevier
DOI: 10.1016/b978-0-08-102828-5.00006-1

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