Objective
As all living organisms, our cells need to feed on a balanced diet to stay healthy and correctly function. To do that, cells adapt their nutrient consumption according to their energetic needs. If the uptake mechanism is impaired, it impacts cell metabolism. Both starving cells & overfeeding cells are a hallmark for the onset and progress of serious diseases like diabetes, cancer or inborn errors of metabolism, which can all be seen as metabolic diseases. These are debilitating conditions that need lifelong treatments, entail poorer life quality and incur a major economic burden. Subjects appear initially healthy and symptoms are often overlooked, but by the time of diagnosis, damage can no longer be reverted. Conversely, early detection could prevent most of the damages by starting specific therapies. However, despite the fact that all metabolic diseases have abnormal cell energetics, there are no tests for cell metabolism in clinical practice. In response, we at METAFORA aim to bring to market METAdiag, the first diagnostic platform able to assess and monitor the metabolic status of our cells. This unique and non-invasive diagnostic system is able to detect abnormal cell energetics by quantifying the levels of nutrient transporters at the cell surface. After proving the reliability and accuracy of our platform at a small scale, we now aim to take a step further towards the market. Thus, in Phase 1 we aim to conduct a Feasibility Study that will help us to assess and achieve the significant milestones influencing the project from the technical, commercial and financial perspectives. Based on proprietary technology and on a strong collaboration network, METAdiag will be uniquely positioned to detect metabolic impairments, allowing clinicians to achieve an earlier diagnosis and patients to receive better management and prognosis. In turn, METAdiag will boost the growth of our company, expecting to generate €42 million in revenues and to hire 22 new people in 5 years.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine neurology epilepsy
- medical and health sciences basic medicine neurology neurodegenerative diseases dementia alzheimer
- medical and health sciences health sciences inflammatory diseases
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences clinical medicine oncology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being
MAIN PROGRAMME
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H2020-EU.3.1.3. - Treating and managing disease
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SMEInst-2016-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75014 Paris
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.