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iTRUST: In-time TReatment of acUte ischaemic STroke

Objective

The problem: Intravenous thrombolysis is by far the most effective treatment of Acute Ischaemic Stroke (AIS), and its use can independently strongly increase the proportion of AIS patients surviving. However, in the emergency setting of AIS an excess of information must be considered by the physician including imaging, clinical presentation and electronic health record data before safely inferring on the suitability of thrombolytic therapy. Still, the therapeutic decision is largely dependent on the capacity of the expert radiologist in predicting what is the outcome for the given patient after applying the pharmacological treatment – a problem further compounded by the heterogeneity in AIS progression.

The solution: iTRUST solution is a clinical decision support system that uses Convolutional Neural Networks to predict the outcome of the AIS for each patient based on the patient’s biomarkers as well as clinical information. The prediction is presented as a probability of infarction when using pharmacological treatment or mechanical recanalization, making the prediction much more useful compared to current methods.

The market: The global AIS diagnosis and treatment market was valued at USD 1.2 billion in 2013 and is estimated to reach a market worth of USD 1.9 billion in 2020 growing at a CAGR of 6.3% from 2014 to 2020. Given the high incidence of AIS cases and the high importance of quickly allocating the appropriate therapeutic intervention, we have reasons to believe that iTRUST solution can generate an accumulated turnover exceeding EUR 32 million, five years post-project.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2016-2017

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Coordinator

CERCARE MEDICAL APS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
INGE LEHMANNS GADE 10
8000 Aarhus C
Denmark

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Danmark Midtjylland Østjylland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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