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An integrative approach for the exploration of melanoma genetic and immunological interactions

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Publications

Exome Sequencing of ABCB5 Identifies Recurrent Melanoma Mutations that Result in Increased Proliferative and Invasive Capacities

Author(s): Géraldine Sana, James P. Madigan, Jared J. Gartner, Marie Fourrez, Jimmy Lin, Nouar Qutob, Jitendra Narayan, Suneet Shukla, Suresh V. Ambudkar, Di Xia, Steven A. Rosenberg, Michael M. Gottesman, Yardena Samuels, Jean-Pierre Gillet
Published in: Journal of Investigative Dermatology, 139/9, 2019, Page(s) 1985-1992.e10, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.01.036

A genome‐wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS ‐mutant melanoma

Author(s): Adi Nagler, David W. Vredevoogd, Michal Alon, Phil F. Cheng, Sophie Trabish, Shelly Kalaora, Rand Arafeh, Victoria Goldin, Mitchell P. Levesque, Daniel S. Peeper, Yardena Samuels
Published in: Pigment Cell & Melanoma Research, 33/2, 2020, Page(s) 334-344, ISSN 1755-1471
Publisher: Basil Blackwell
DOI: 10.1111/pcmr.12825

UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

Author(s): Yochai Wolf, Osnat Bartok, Sushant Patkar, Gitit Bar Eli, Sapir Cohen, Kevin Litchfield, Ronen Levy, Alejandro Jiménez-Sánchez, Sophie Trabish, Joo Sang Lee, Hiren Karathia, Eilon Barnea, Chi-Ping Day, Einat Cinnamon, Ilan Stein, Adam Solomon, Lital Bitton, Eva Pérez-Guijarro, Tania Dubovik, Shai S. Shen-Orr, Martin L. Miller, Glenn Merlino, Yishai Levin, Eli Pikarsky, Lea Eisenbach, Arie Admon
Published in: Cell, 179/1, 2019, Page(s) 219-235.e21, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.08.032

Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Author(s): Shelly Kalaora, Joo Sang Lee, Eilon Barnea, Ronen Levy, Polina Greenberg, Michal Alon, Gal Yagel, Gitit Bar Eli, Roni Oren, Aviyah Peri, Sushant Patkar, Lital Bitton, Steven A. Rosenberg, Michal Lotem, Yishai Levin, Arie Admon, Eytan Ruppin, Yardena Samuels
Published in: Nature Communications, 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14639-9