The ERC NOMLI project has been exploring nanoscale optomechanical systems evolving in liquids. This research was at the frontier of condensed matter, fluidics, optics, quantum physics, biophysics, engineering and nanotechnology.
Now established as a class of elementary quantum systems on their own, optomechanical resonators have recently pushed our capabilities to probe forces with higher sensitivity and time resolution, at the quantum limit of detection. In NOMLI, we used these capabilities to explore physical interactions in complex environments such as liquids and artificial fluids, or in interaction with biological objects, answering open questions in all these contexts.
Outputs of the project have been in basic science (polaritonic effects in optomechanics) but also in more practical fields, with the development of a micro-rheology method that enables characterizing very tiny liquid amounts and reveal their background viscosity. Biomedical application of this method is currently explored for diagnosis. More generally, NOMLI has established instruments and measurement protocols to gain in sensitivity and time-resolution using optomechanical probes that measure these complex physical systems. This has led to new instruments for biophysics and atomic force spectroscopy, which will impact on the elucidation of micro-biological processes.