Objective
How we decide between different alternatives is a central question to cognitive neuroscience. Decisions may appear trivial (selecting between two meals), or sophisticated and long reaching (deciding whom to marry). Decisions constitute a highly dynamical process of evidence accumulation. These dynamics can be represented in cortical oscillations, which have attracted great interest as a key mechanism that coordinates fast computations.
While a few studies have investigated the role of cortical oscillations in decision making, the underlying mechanisms translating neurochemical activity into network dynamics and ultimately into choice remain unknown. Although neuromodulator effects are well described at the cellular level, their network effects during high-level behaviours are not well understood. There is however evidence that neuromodulators also control cortical oscillations and that this may have behavioural relevance. For a mechanistic understanding of human decision making, it is essential to (1) study its fast temporal cortical dynamics and (2) understand how neurochemical signalling gives rise to network dynamics and ultimately to cognition. Biophysical network models are excellent tools for linking these different levels of investigation. Such an understanding is critically important not only from a basic science perspective, it will also further our understanding of psychiatric diseases, which are often characterized by anomalies in neurochemical systems, neural oscillations and decision making.
The novel approach that is core to this proposal is to investigate whether and how neurochemical systems guide decision behaviour by modulating cortical dynamics. To achieve this ambitious goal, I will use a combination of imaging methods with computational modelling, pharmacological challenges and electrical brain stimulation. This new approach will allow me to move towards a mechanistic understanding of the systems-level dynamics underlying decision making.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-COG - Consolidator Grant
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2017-COG
See all projects funded under this callHost institution
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
40225 Dusseldorf
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.