Description du projet
Un dispositif mobile pour le diagnostic des maladies porcines
L’efficacité de divers médicaments et vaccins ont permis de réduire la charge directe des maladies du bétail dans les pays développés. Cependant, les systèmes surpeuplés modernes de production animale restent exposés aux agents infectieux et aux maladies infectieuses potentiellement lourds de conséquences pour la santé animale et l’élevage. Pour faire face à la menace d’épidémies, le projet SWINOSTICS, financé par l’UE, se propose de développer un outil de diagnostic sur site qui fournit, en quelques minutes, des résultats relatifs à six maladies porcines associées à des virus. Le dispositif de biodétection basé sur la nanotechnologie utilise des anticorps pour évaluer rapidement et simultanément plusieurs échantillons, ce qui permet de s’affranchir du laborieux processus d’essai conventionnel. La sensibilité et la spécificité élevées de l’outil SWINOSTICS permettront de prendre, au niveau local, des décisions visant à prévenir la propagation des maladies.
Objectif
The increased population density in modern animal production systems has made them vulnerable to various transboundary infectious agents & diseases. During the last decades in the developed world, a reduction in the direct burden of livestock diseases has been observed, because of more effective drugs & vaccines. However, the total impact may actually be increasing, because in a highly-interconnected world, the effects of diseases extend far beyond animal sickness & mortality. Therefore, early diagnosis and establishment of reliable countermeasures to infectious disease outbreaks is essential to limit severe biophysical and socio-economic consequences.
To date, the time between initial disease outbreak and laboratory confirmation of the etiologic infectious agent can be up to several weeks. Reliable & simple diagnostic testing directly on site would enable rapid local decision making, which is crucial to prevent further spreading of the disease.
Silicon-based Photonic Integrated Circuits (PIC) have been demonstrated as a powerful platform for biosensing systems. In combination with integrated monoclonal antibodies, they can provide portable multiplex detection of proteins with sensitivity & specificity previously not realized. SWINOSTICS addresses the sector needs, by developing a novel field diagnostic device, based on advanced, proven, bio-sensing technologies to tackle viruses causing epidemics in swine farms and leading to relevant economic damages, complying to the objectives of the STAR-IDAZ. The diagnostic device will allow threat assessment at the farm level, with the analytical quality of commercial laboratories. The device will be developed for a panel of 6 important swine diseases. The device will be portable & will provide results in 10 minutes for 5 samples simultaneously, making it highly suitable for field use. It is based on 3 lab-verified concepts: a) PIC technology, b) Label-free optical detection, c) patented nano-deposition technology.
Champ scientifique
- natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acids
- medical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenza
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- engineering and technologymedical engineeringmedical laboratory technologydiagnostic technologies
- agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandry
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Programme(s)
Régime de financement
IA - Innovation actionCoordinateur
1060 Lefkosia
Chypre
L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention.