Descrizione del progetto
Dispositivo mobile per la diagnosi delle malattie suine
Farmaci e vaccini efficaci hanno ridotto l’onere diretto delle malattie del bestiame nei paesi sviluppati, ma i moderni sistemi di produzione animale sovrappopolati rimangono vulnerabili agli agenti infettivi e alle malattie, che possono avere gravi conseguenze per la salute degli animali e per il loro allevamento. Per affrontare la minaccia di epidemie, il progetto SWINOSTICS, finanziato dall’UE, propone lo sviluppo di uno strumento diagnostico in loco che fornisca in pochi minuti risultati per sei diverse malattie suine associate a virus. Il dispositivo di biorilevamento basato sulle nanotecnologie utilizza gli anticorpi per valutare rapidamente più campioni allo stesso tempo, superando il laborioso processo di analisi tradizionale. L’elevata sensibilità e specificità dello strumento SWINOSTICS consentirà di prendere decisioni a livello locale per prevenire la diffusione delle malattie.
Obiettivo
The increased population density in modern animal production systems has made them vulnerable to various transboundary infectious agents & diseases. During the last decades in the developed world, a reduction in the direct burden of livestock diseases has been observed, because of more effective drugs & vaccines. However, the total impact may actually be increasing, because in a highly-interconnected world, the effects of diseases extend far beyond animal sickness & mortality. Therefore, early diagnosis and establishment of reliable countermeasures to infectious disease outbreaks is essential to limit severe biophysical and socio-economic consequences.
To date, the time between initial disease outbreak and laboratory confirmation of the etiologic infectious agent can be up to several weeks. Reliable & simple diagnostic testing directly on site would enable rapid local decision making, which is crucial to prevent further spreading of the disease.
Silicon-based Photonic Integrated Circuits (PIC) have been demonstrated as a powerful platform for biosensing systems. In combination with integrated monoclonal antibodies, they can provide portable multiplex detection of proteins with sensitivity & specificity previously not realized. SWINOSTICS addresses the sector needs, by developing a novel field diagnostic device, based on advanced, proven, bio-sensing technologies to tackle viruses causing epidemics in swine farms and leading to relevant economic damages, complying to the objectives of the STAR-IDAZ. The diagnostic device will allow threat assessment at the farm level, with the analytical quality of commercial laboratories. The device will be developed for a panel of 6 important swine diseases. The device will be portable & will provide results in 10 minutes for 5 samples simultaneously, making it highly suitable for field use. It is based on 3 lab-verified concepts: a) PIC technology, b) Label-free optical detection, c) patented nano-deposition technology.
Campo scientifico
- natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acids
- medical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenza
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- engineering and technologymedical engineeringmedical laboratory technologydiagnostic technologies
- agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandry
Parole chiave
Programma(i)
Meccanismo di finanziamento
IA - Innovation actionCoordinatore
1060 Lefkosia
Cipro
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