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Exploring the bacterial cell cycle to re-sensitize antibiotic-resistant bacteria

Publications

DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches

Author(s): Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F. Laine, Pedro M. Pereira, Lucas von Chamier, Mia Conduit, Mariana G. Pinho, Guillaume Jacquemet, Séamus Holden, Mike Heilemann, Ricardo Henriques
Published in: Communications Biology, Issue 23993642, 2022, Page(s) 688, ISSN 2399-3642
Publisher: Nature Portfolio
DOI: 10.1038/s42003-022-03634-z

BPEI-Induced Delocalization of PBP4 Potentiates β-lactams Against MRSA.

Author(s): Hill, Melissa A.; Lam, Anh K.; Reed, Patricia; Harney, Madeline C.; Wilson, Beatrice A.; Moen, Erika L.; Wright, Summer N.; Pinho, Mariana G.; Rice, Charles V.
Published in: Biochemistry, Issue 2, 2019, ISSN 0006-2960
Publisher: American Chemical Society
DOI: 10.1021/acs.biochem.9b00523

Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan

Author(s): Truc Do, Kaitlin Schaefer, Ace George Santiago, Kathryn A. Coe, Pedro B. Fernandes, Daniel Kahne, Mariana G. Pinho, Suzanne Walker
Published in: Nature Microbiology, Issue 5/2, 2020, Page(s) 291-303, ISSN 2058-5276
Publisher: Springer Nature
DOI: 10.1038/s41564-019-0632-1

eHooke: A tool for automated image analysis of spherical bacteria based on cell cycle progression

Author(s): Bruno M. Saraiva; Ludwig Krippahl; Sergio R. Filipe; Ricardo Henriques; Mariana G. Pinho
Published in: Biological Imaging, Issue 1, 2021, ISSN 2633-903X
Publisher: Cambridge University Press
DOI: 10.1017/s2633903x21000027

The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity

Author(s): João M. Monteiro, Gonçalo Covas, Daniela Rausch, Sérgio R. Filipe, Tanja Schneider, Hans-Georg Sahl, Mariana G. Pinho
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-41461-1

SEDS–bPBP pairs direct lateral and septal peptidoglycan synthesis in Staphylococcus aureus

Author(s): Nathalie T. Reichmann, Andreia C. Tavares, Bruno M. Saraiva, Ambre Jousselin, Patricia Reed, Ana R. Pereira, João M. Monteiro, Rita G. Sobral, Michael S. VanNieuwenhze, Fábio Fernandes, Mariana G. Pinho
Published in: Nature Microbiology, Issue 4/8, 2019, Page(s) 1368-1377, ISSN 2058-5276
Publisher: Nature Research
DOI: 10.1038/s41564-019-0437-2

Revisiting the Role of VraTSR in Staphylococcus aureus Response to Cell Wall-Targeting Antibiotics

Author(s): Pedro B. Fernandes, Patricia Reed, João M. Monteiro, Mariana G. Pinho
Published in: Journal of Bacteriology, Issue 00219193, 2022, Page(s) e0016222, ISSN 0021-9193
Publisher: American Society for Microbiology
DOI: 10.1128/jb.00162-22

Reassessment of the distinctive geometry of Staphylococcus aureus cell division

Author(s): Bruno M. Saraiva, Moritz Sorg, Ana R. Pereira, Mário J. Ferreira, Léo C. Caulat, Nathalie T. Reichmann, Mariana G. Pinho
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-17940-9

Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses

Author(s): Figueiredo J, Henriques MX, Catalão MJ, Pinheiro S, Narciso AR, Mesquita F, Saraiva BM, Carido M, Cabanes D, Pinho MG, Filipe SR.
Published in: PLoS Pathogens, 2022, ISSN 1553-7366
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1010516

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