Stroke diagnostic imaging performed with ultrafast ultrasound localization microscopy (uULM)

Project Information

ResolveStroke

Grant agreement ID: 772786

DOI

10.3030/772786

Project closed

EC signature date 26 March 2018

Start date 1 September 2018

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 995 098,00

EU contribution

€ 1 995 098,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (21)

Sensing ultrasound localization microscopy for the visualization of glomeruli in living rats and humans

Author(s): Louise Denis Sylvain Bodard Vincent Hingot Arthur Chavignon Jacques Battaglia Gilles Renault Franck Lager Abderrahmane Aissani Olivier Hélénon Jean-Michel Correas Olivier Couture
Published in: EbioMedicine, 2023, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104578

3D transcranial Ultrasound Localization Microscopy for discrimination between ischemic and hemorrhagic stroke in early phase

Author(s): Arthur Chavignon; Vincent Hingot; Cyrille Orset; Denis Vivien; Olivier Couture
Published in: Scientific Reports, Issue 12, 2022, Page(s) 14607, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-18025-x

Measuring image resolution in Ultrasound Localization Microscopy

Author(s): V. Hingot, A. Chavignon, B. Heiles, O. Couture
Published in: IEEE Transactions on Medical Imaging, 2021, Page(s) 1-1, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2021.3097150

Microvascular flow dictates the compromise between spatial resolution and acquisition time in Ultrasound Localization Microscopy

Author(s): Vincent Hingot, Claudia Errico, Baptiste Heiles, Line Rahal, Mickael Tanter, Olivier Couture
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-38349-x

Volumetric ultrasound localization microscopy with diverging cylindrical waves

Author(s): Antoine Coudert, Arthur Chavignon, Louise Denis, Olivier Couture
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2024, Page(s) 1-1, ISSN 0885-3010
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2024.3375896

Ultrafast Radial Modulation Imaging

Author(s): Pauline Muleki-Seya, Kailiang Xu, Mickael Tanter, Olivier Couture
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Issue 67/3, 2020, Page(s) 598-611, ISSN 0885-3010
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2019.2949046

Early Ultrafast Ultrasound Imaging of Cerebral Perfusion correlates with Ischemic Stroke outcomes and responses to treatment in Mice

Author(s): Vincent Hingot, Camille Brodin, Florent Lebrun, Baptiste Heiles, Audrey Chagnot, Mervé Yetim, Maxime Gauberti, Cyrille Orset, Mickael Tanter, Olivier Couture, Thomas Deffieux, Denis Vivien
Published in: Theranostics, Issue 10/17, 2020, Page(s) 7480-7491, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.44233

Volumetric Ultrasound Localization Microscopy

Author(s): Louise Denis, Georges Chabouh, Baptiste Heiles, Olivier Couture
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2024, Page(s) 1-1, ISSN 0885-3010
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2024.3485556

Ultrasound Localization Microscopy for the Assessment of Microvascular Circulation in Ischemic Perinatal Stroke

Author(s): Adrian P. Regensburger, Felix Wachter, Louise Denis, Henriette Mandelbaum, Frauke Schey, Adrian Buehler, Gregor Siebenlist, Simone Schwarz, Susanne Schulz-Heise, Oliver Rompel, Regina Trollmann, Joachim Woelfle, Jörg Jüngert, Olivier Couture, Heiko Reutter, Gregor Hanslik, Ferdinand Knieling
Published in: Stroke, Issue 55, 2025, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.124.048390

First clinical utility of sensing Ultrasound Localization Microscopy (sULM): identifying renal pseudotumors

Author(s): Sylvain Bodard, Louise Denis, Georges Chabouh, Dany Anglicheau, Olivier Hélénon, Jean-Michel Correas, Olivier Couture
Published in: Theranostics, Issue 15, 2024, Page(s) 233-244, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.100897

Deep and Complex Vascular Anatomy in the Rat Brain Described With Ultrasound Localization Microscopy in 3D

Author(s): Arthur Chavignon, Baptiste Heiles, Vincent Hingot, Cyrille Orset, Denis Vivien, Olivier Couture
Published in: IEEE Open Journal of Ultrasonics, Ferroelectrics, and Frequency Control, Issue 3, 2024, Page(s) 203-209, ISSN 2694-0884
Publisher: IEEE
DOI: 10.1109/ojuffc.2023.3342751

Performance benchmarking of microbubble-localization algorithms for ultrasound localization microscopy

Author(s): Baptiste Heiles; Arthur Chavignon; Vincent Hingot; Pauline Lopez; Eliott Teston; Olivier Couture
Published in: Nature Biomedical Engineering, Issue 6, 2022, Page(s) 605-616, ISSN 2157-846X
Publisher: Nature
DOI: 10.1038/s41551-021-00824-8

Volumetric ultrasound localization microscopy of the whole brain microvasculature

Author(s): Olivier Couture, Baptiste Heiles, Vincent Hingot, Hicham Serroune, David Maresca, Sophie Pezet, Mathieu Pernot, Mickael Tanter, Arthur Chavignon, Antoine Bergel
Published in: IEEE OUFFC, 2022, ISSN 2694-0884
Publisher: IEEE
DOI: 10.21203/rs.3.rs-1198910/v1

Super-resolution Ultrasound Imaging

Author(s): Kirsten Christensen-Jeffries, Olivier Couture, Paul A. Dayton, Yonina C. Eldar, Kullervo Hynynen, Fabian Kiessling, Meaghan O'Reilly, Gianmarco F. Pinton, Georg Schmitz, Meng-Xing Tang, Mickael Tanter, Ruud J.G. van Sloun
Published in: Ultrasound in Medicine & Biology, Issue 46/4, 2020, Page(s) 865-891, ISSN 0301-5629
Publisher: Elsevier BV
DOI: 10.1016/j.ultrasmedbio.2019.11.013

Ultrasound localization microscopy of the human kidney allograft on a clinical ultrasound scanner

Author(s): Sylvain Bodard Louise Denis Vincent Hingot Arthur Chavignon Olivier Helenon Dany Anglicheau Olivier Couture Jean-Michel Correas
Published in: Kidney International, 2023, ISSN 0085-2538
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2023.01.027

3D Transcranial ultrasound localization microscopy reveals major arteries in the sheep brain

Author(s): A. Coudert, L. Denis, A. Chavignon, S. Bodard, M. Naveau, P.P. Sistiaga, R. Saulnier, C. Orset, D. Vivien, C. Chappard, O. Couture
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2024, Page(s) 1-1, ISSN 0885-3010
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2024.3432998

Ultrasound Super‐Resolution Imaging of Neonatal Cerebral Vascular Reorganization

Author(s): Simone Schwarz, Louise Denis, Emmanuel Nedoschill, Adrian Buehler, Vera Danko, Alina C. Hilger, Francisco Brevis Nuñez, Nikola R. Dürr, Martin Schlunz‐Hendann, Friedhelm Brassel, Ursula Felderhoff‐Müser, Heiko Reutter, Joachim Woelfle, Jörg Jüngert, Christian Dohna‐Schwake, Nora Bruns, Adrian P. Regensburger, Olivier Couture, Henriette Mandelbaum, Ferdinand Knieling
Published in: Advanced Science, Issue 12, 2025, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202415235

3D Transcranial Ultrasound Localization Microscopy in the Rat Brain With a Multiplexed Matrix Probe

Author(s): Arthur Chavignon, Baptiste Heiles, Vincent Hingot, Cyrille Orset, Denis Vivien, Olivier Couture
Published in: IEEE Transactions on Biomedical Engineering, Issue 69, 2024, Page(s) 2132-2142, ISSN 0018-9294
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2021.3137265

3D transcranial ultrasound localization microscopy in awake mice: protocol and open-source pipeline

Author(s): Georges Chabouh, Louise Denis, Myriam Abioui-Mourgues, Jean-Baptiste Deloges, Jacques Battaglia, Arthur Chavignon, Baptiste Heiles, Basile Pradier, Sylvain Bodard, Denis Vivien, Cyrille Orset, Olivier Couture
Published in: Communications Engineering, Issue 4, 2025, ISSN 2731-3395
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s44172-025-00415-4

Whole organ volumetric sensing Ultrasound Localization Microscopy for characterization of kidney structure

Author(s): Georges Chabouh, Louise Denis, Sylvain Bodard, Franck Lager, Gilles Renault, arthur chavignon, olivier couture
Published in: IEEE Transactions on Medical Imaging, 2023, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1101/2023.08.31.555780

Ultrafast 3D Ultrasound Localization Microscopy Using a 32 $\times$ 32 Matrix Array

Author(s): Baptiste Heiles; Mafalda Correia; Vincent Hingot; Mathieu Pernot; Jean Provost; Mickael Tanter; Olivier Couture
Published in: IEEE TRANSACTIONS ON MEDICAL IMAGING, Issue 1, 2019, Page(s) 2005, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2018.2890358