Biotechnology for investigating cell fate choice

Project Information

CellFateTech

Grant agreement ID: 772798

DOI

10.3030/772798

Project terminated on 29 November 2022

EC signature date 29 January 2018

Start date 1 April 2018

End date 30 November 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 876 618,00

EU contribution

€ 1 876 618,00

Coordinated by

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

StemBond hydrogels optimise the mechanical microenvironment for embryonic stem cells

Author(s): Céline Labouesse; Chibeza C. Agley; Bao Xiu Tan; Moritz Hofer; Alex Winkel; Giuliano Giuseppe Stirparo; Hannah T. Stuart; Christophe M. Verstreken; William Mansfield; Paul Bertone; Kristian Franze; José C. R. Silva; Kevin J. Chalut
Published in: Nature Communications, Issue 4, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/768762

Microfluidic platform for 3D cell culture with live imaging and clone retrieval

Author(s): Carla Mulas, Andrew C. Hodgson, Timo N. Kohler, Chibeza C. Agley, Peter Humphreys, Hans Kleine-Brüggeney, Florian Hollfelder, Austin Smith, Kevin J. Chalut
Published in: Lab on a Chip, Issue 20/14, 2020, Page(s) 2580-2591, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0lc00165a

A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium

Author(s): McGinn, J., Hallou, A., Han, S. et al.
Published in: Nature Cell Biology, Issue 6, 2021, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-021-00679-w

Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate

Author(s): Henry De Belly Aki Stubb Ayaka Yanagida Philip H. Jones Ewa K. Paluch Kevin J. Chalut
Published in: Cell Stem Cell, Issue 6, 2021, ISSN 1875-9777
Publisher: Cell Stem Cell
DOI: 10.1016/j.stem.2020.10.018

Cell surface fluctuations regulate early embryonic lineage sorting

Author(s): Ayaka Yanagida Elena Corujo-Simon Christopher K. Revell Ewa K. Paluch Jennifer Nichols Kevin J. Chalut
Published in: Cell, 2022, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2022.01.022

Niche stiffness underlies the ageing of central nervous system progenitor cells

Author(s): Michael Segel, Björn Neumann, Myfanwy F. E. Hill, Isabell P. Weber, Carlo Viscomi, Chao Zhao, Adam Young, Chibeza C. Agley, Amelia J. Thompson, Ginez A. Gonzalez, Amar Sharma, Staffan Holmqvist, David H. Rowitch, Kristian Franze, Robin J. M. Franklin, Kevin J. Chalut
Published in: Nature, Issue 573/7772, 2019, Page(s) 130-134, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1484-9

Long‐Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation

Author(s): Hans Kleine‐Brüggeney, Liisa D. van Vliet, Carla Mulas, Fabrice Gielen, Chibeza C. Agley, José C. R. Silva, Austin Smith, Kevin Chalut, Florian Hollfelder
Published in: Small, Issue 15/5, 2019, Page(s) 1804576, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201804576

Embryonic stem cells become mechanoresponsive upon exit from ground state of pluripotency

Author(s): C. M. Verstreken, C. Labouesse, C. C. Agley, K. J. Chalut
Published in: Open Biology, Issue 9/1, 2019, Page(s) 180203, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.180203

Cortical cell stiffness is independent of substrate mechanics

Author(s): Johannes Rheinlaender; Andrea Dimitracopoulos; Bernhard Wallmeyer; Nils M. Kronenberg; Kevin J. Chalut; Malte C. Gather; Timo Betz; Guillaume Charras; Guillaume Charras; Kristian Franze
Published in: Nature Materials, Issue 3, 2020, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1101/829614