Septins: from bacterial entrapment to cellular immunity

Project Information

ENTRAPMENT

Grant agreement ID: 772853

DOI

10.3030/772853

EC signature date 20 September 2018

Start date 1 April 2019

End date 31 March 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 744 407,00

EU contribution

€ 2 744 407,00

Coordinated by

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (13)

The zebrafish as a novel model for the in vivo study of Toxoplasma gondii replication and interaction with macrophages

Author(s): Nagisa Yoshida, Marie-Charlotte Domart, Christopher J. Peddie, Artur Yakimovich, Maria J. Mazon-Moya, Thomas A. Hawkins, Lucy Collinson, Jason Mercer, Eva-Maria Frickel, Serge Mostowy
Published in: Disease Models & Mechanisms, Issue 13/7, 2020, Page(s) dmm043091, ISSN 1754-8403
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dmm.043091

Shigella sonnei

Author(s): Vincenzo Torraca, Kathryn Holt, Serge Mostowy
Published in: Trends in Microbiology, Issue 28/8, 2020, Page(s) 696-697, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2020.02.011

A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition

Author(s): Fatima R. Ulhuq, Margarida C. Gomes, Gina M. Duggan, Manman Guo, Chriselle Mendonca, Grant Buchanan, James D. Chalmers, Zhenping Cao, Holger Kneuper, Sarah Murdoch, Sarah Thomson, Henrik Strahl, Matthias Trost, Serge Mostowy, Tracy Palmer
Published in: Proceedings of the National Academy of Sciences, Issue 117/34, 2020, Page(s) 20836-20847, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2006110117

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

Author(s): Vincenzo Torraca, Myrsini Kaforou, Jayne Watson, Gina M. Duggan, Hazel Guerrero-Gutierrez, Sina Krokowski, Michael Hollinshead, Thomas B. Clarke, Rafal J. Mostowy, Gillian S. Tomlinson, Vanessa Sancho-Shimizu, Abigail Clements, Serge Mostowy
Published in: PLOS Pathogens, Issue 15/12, 2019, Page(s) e1008006, ISSN 1553-7374
Publisher: PLOS
DOI: 10.1371/journal.ppat.1008006

Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection

Author(s): Artur Yakimovich, Moona Huttunen, Jerzy Samolej, Barbara Clough, Nagisa Yoshida, Serge Mostowy, Eva-Maria Frickel, Jason Mercer
Published in: mSphere, Issue 5/5, 2020, ISSN 2379-5042
Publisher: ASM
DOI: 10.1128/msphere.00836-20

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Author(s): Daniel J. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H. Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E. Adamopoulos, Khosrow Adeli, Timon E. Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B. Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N. Agrewala, Alexander A
Published in: Autophagy, Issue 17/1, 2021, Page(s) 1-382, ISSN 1554-8627
Publisher: Landes Bioscience
DOI: 10.1080/15548627.2020.1797280

The history of septin biology and bacterial infection

Author(s): Stevens Robertin, Serge Mostowy
Published in: Cellular Microbiology, Issue 22/4, 2020, ISSN 1462-5814
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cmi.13173

Emerging technologies and infection models in cellular microbiology

Author(s): Ana Teresa López-Jiménez, Serge Mostowy
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-26641-w

Mechanistic insight into bacterial entrapment by septin cage reconstitution

Author(s): Damián Lobato-Márquez, Jingwei Xu, Gizem Özbaykal Güler, Adaobi Ojiakor, Martin Pilhofer, Serge Mostowy
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24721-5

In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

Author(s): Håkon Høgset, Conor C. Horgan, James P. K. Armstrong, Mads S. Bergholt, Vincenzo Torraca, Qu Chen, Timothy J. Keane, Laurence Bugeon, Margaret J. Dallman, Serge Mostowy, Molly M. Stevens
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19827-1

The Case for Modeling Human Infection in Zebrafish

Author(s): Margarida C. Gomes, Serge Mostowy
Published in: Trends in Microbiology, Issue 28/1, 2020, Page(s) 10-18, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2019.08.005

Possible role of L-form switching in recurrent urinary tract infection

Author(s): Katarzyna M. Mickiewicz, Yoshikazu Kawai, Lauren Drage, Margarida C. Gomes, Frances Davison, Robert Pickard, Judith Hall, Serge Mostowy, Phillip D. Aldridge, Jeff Errington
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12359-3

Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

Author(s): Alon Schneider Hait, David Olagnier, Vanessa Sancho-Shimizu, Kristian Alsbjerg Skipper, Marie Helleberg, Simon Muller Larsen, Chiranjeevi Bodda, Liviu Ionut Moldovan, Fanghui Ren, Nanna-Sophie Brinck Andersen, Michelle M. Thomsen, Mette Ratzer Freytag, Sathya Darmalinggam, Isobel Parkes, Darshana D. Kadekar, Stine Hess Rahbek, Demi van der Horst, Lasse Sommer Kristensen, Kristina Eriksson, Jørgen
Published in: Science Immunology, Issue 5/54, 2020, ISSN 2470-9468
Publisher: AAAS
DOI: 10.1126/sciimmunol.abc2691