Molecular diagnostics through DNA modification and interfacial engineering

Deliverables

Report on Incorporation of Modified DNA in Nanoarchitectures

Report on methods for DNA enzymatic extension and phosphoramidite synthesis and ligation using modified bases and their use in construction of nanoarchitectures

Report on Synthesis of Modified Nucleotides, Oligonucleotides and Polynucleotides, and of Sequence-Specific Functional DNA Binders

Report on synthesis of modified and their incorporation into modified oligonucleotide and kilobase pair DNA and of sequencespecific DNA binders with inbuilt functionalities

Report on Attachment of Modified DNA to Substrates

Review on methods of attachment of modified DNA to surfaces

Publications

Microfluidics and materials for smart water monitoring: A review

Author(s): Janire Saez, Raquel Catalan-Carrio, Róisín M Owens, Lourdes Basabe-Desmonts, Fernando Benito-Lopez
Published in: Analytica Chimica Acta, Issue 1186, 2021, Page(s) 338392, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/j.aca.2021.338392

A method for the controllable fabrication of optical fiber-based localized surface plasmon resonance sensors

Author(s): Alba Calatayud-Sanchez, Angel Ortega-Gomez, Javier Barroso, Joseba Zubia, Fernando Benito-Lopez, Joel Villatoro & Lourdes Basabe-Desmonts
Published in: Scientific Reports, Issue 12, 2022, Page(s) Article number: 9566, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-13707-y

Continuous monitoring of cell transfection efficiency with micropatterned substrates

Author(s): Enrique Azuaje-Hualde, Melania Rosique, Alba Calatayud-Sanchez, Fernando Benito-Lopez, Marian M. de Pancorbo, Lourdes Basabe-Desmonts
Published in: Biotechnology and Bioengineering, Issue 118, 2021, Page(s) 2626-2636, ISSN 1097-0290
Publisher: Wiley
DOI: 10.1002/bit.27783

Naked eye Y amelogenin gene fragment detection using DNAzymes on a paper-based device.

Author(s): Enrique Azuaje-Hualde; Susana Arroyo-Jimenez; Gaizka Garai-Ibabe; Marian M. de Pancorbo; Fernando Benito-Lopez; Lourdes Basabe-Desmonts; Lourdes Basabe-Desmonts
Published in: Anal Chim Acta, Issue 1123, 2020, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/j.aca.2020.05.010

Large Volume Self-powered Disposable Microfluidics by the Integration of Modular Polymer Micropumps with Plastic Microfluidic Cartridges

Author(s): Jaione Etxebarria-Elezgarai; Yara Alvarez-Braña; Rosa Garoz-Sanchez; Fernando Benito-Lopez; Lourdes Basabe-Desmonts
Published in: Ind Eng Chem Res, Issue 59, 2020, ISSN 1226-086X
Publisher: Korean Society of Industrial Engineering Chemistry
DOI: 10.1021/acs.iecr.0c03398

The Role of Order in the Mechanism of Charge Transport across Single-Stranded and Double-Stranded DNA Monolayers in Tunnel Junctions

Author(s): N. K. Gupta, E. A. Wilkinson, S. K. Karuppannan, L. Bailey, A. Vilan. Z. Zhang, D.-C. Qi, A. Tadich, E. Tuite, A. Pike, J. H. R. Tucker, C. A. Nijhuis
Published in: J Am Chem Soc, Issue 143, 2021, Page(s) 20309-20319, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.1c09549

Development of an alginate/TiO2-based microfluidic biosystem for chrono-sampling and sensing of glucose in artificial sweat

Author(s): Sandra Garcia-Rey, Eva Gil-Hernandez, Udara Bimendra Gunatilake, Lourdes Basabe-Desmonts, Fernando Benito-Lopez
Published in: Sensors and Actuators B: Chemical, Issue 382, 2023, Page(s) 133514, ISSN 0925-4005
Publisher: Elsevier BV
DOI: 10.1016/j.snb.2023.133514

Self-Priming Enzymatic Fabrication of Multiply Modified DNA

Author(s): Colette J. Whitfield, Rachel C. Little, Kasid Khan, Kuniharu Ijiro, Bernard A. Connolly, Eimer M. Tuite, Andrew R. Pike
Published in: Chemistry - A European Journal, Issue 24/57, 2018, Page(s) 15267-15274, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201801976

Ionogel-based hybrid polymer-paper handheld platform for nitrite and nitrate determination in water samples

Author(s): Raquel Catalan-Carrio; Janire Saez; Luis Ángel Fernández Cuadrado; Gorka Arana; Lourdes Basabe-Desmonts; Fernando Benito-Lopez
Published in: Analytica Chimica Acta, Issue 1205, 2022, Page(s) 339753, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/j.aca.2022.339753

Colorimetric Determination of Glucose in Sweat Using an Alginate-Based Biosystem

Author(s): Sandra Garcia-Rey; Eva Gil-Hernandez; Lourdes Basabe-Desmonts; Fernando Benito-Lopez
Published in: Polymers (Basel), Issue 15, 2023, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym15051218

Paper based microfluidic platform for single-step detection of mesenchymal stromal cells secreted VEGF

Author(s): Enrique Azuaje-Hualde; Marian M. de Pancorbo; Fernando Benito-Lopez; Lourdes Basabe-Desmonts
Published in: Analytica Chimica Acta Volume 1199, 22 March 2022,, Issue 1199, 2022, Page(s) 339588, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/j.aca.2022.339588

Exploiting DNA surfaces for sensing and nanomaterial applications

Author(s): Samantha Marie Louise Lunn
Published in: 2018
Publisher: Newcastle University

Controllable inkjet printing of graphene oxide and hydrophilic nanomaterials

Author(s): Thomas Alexander Bamford
Published in: 2020
Publisher: Newcastle University

Designer DNA for sensing and nanomaterials

Author(s): Rachel Clare Little
Published in: 2019
Publisher: Newcastle University

Cover Article: Selective Ultrasensitive Optical Fiber Nanosensors Based on Plasmon Resonance Energy Transfer

Author(s): Javier Barroso; Angel Ortega-Gomez; Alba Calatayud-Sanchez; Joseba Zubia; Fernando Benito-Lopez; Joel Villatoro; Joel Villatoro; Lourdes Basabe-Desmonts; Lourdes Basabe-Desmonts
Published in: ACS Sensors, Issue 5, 2020, Page(s) 2018-2024, ISSN 2379-3694
Publisher: American Chemical Society

Intellectual Property Rights

METHODS FOR DETECTING TARGET POLYNUCLEOTIDES

Application/Publication number: 20 19050512
Date: 2019-02-25