Objective The current process of drug development is lengthy and inefficient. Only 1 out of approximately 10,000 drug molecules enters the market. Therefore more effective medicines, demanded by society, cannot be provided by pharmaceutical industry. To fill this gap, Open Research Biopharmaceutical Internships Support (ORBIS) proposes that the high attrition rate of new drug candidates might be reduced by over 20% by improving early stage R&D productivity. The overarching objective of ORBIS is therefore to form an international and inter-sectoral academic and industrial network. The action is aimed at improving the preclinical pathway of medicine development concentrating on processes and technologies. The goal is to integrate multidisciplinary research by involving academia and industry from EU (Poland, Ireland, Finland, Germany and Czech Republic), EU associated country (Ukraine) and US to address the poor drug bioavailability as 70% of actives have solubility and/or membrane permeability problems. The action is addressed at selected molecules of class II and IV of Biopharmaceutics Classification System, to improve their pharmaceutical potential. The complementary consortium comprises experts in computations, physical chemistry, material science, nanotechnology, pharmacy, pharmacology and bioanalysis. The secondments will create a stimulating environment for early stage researchers to advance their individual career and soft skills. EU scientists will amalgamate their expertise in drug synthesis and dissolution, oral formulations, and bioanalytical methods with the knowledge on dermal research provided by the US partner. ORBIS will consolidate the existing links, promote long-term cooperation and exchange of knowledge between beneficiaries and partners. ORBIS will also enhance dissemination of new research outcomes and raise the awareness among the general public of the importance of drug delivery research that makes new drugs more accessible and affordable for society. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsengineering and technologynanotechnologynatural scienceschemical sciencesphysical chemistrysocial sciencespolitical sciencesgovernment systems Keywords medicinal chemistry preformulation pharmaceutical technology drug delivery dosage forms processability biorelevant dissolution biomedical analysis biopharmaceutics technology transfer Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Topic(s) MSCA-RISE-2017 - Research and Innovation Staff Exchange Call for proposal H2020-MSCA-RISE-2017 See other projects for this call Funding Scheme MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinator UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU Net EU contribution € 737 865,00 Address UL. FREDRY 10 61-701 Poznan Poland See on map Region Makroregion północno-zachodni Wielkopolskie Miasto Poznań Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 737 865,00 Participants (11) Sort alphabetically Sort by Net EU contribution Expand all Collapse all JOINT STOCK COMPANY FARMAK Ukraine Net EU contribution € 189 000,00 Address 63, FRUNZE STR. 04080 Kijev See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 189 000,00 THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Ireland Net EU contribution € 99 000,00 Address COLLEGE GREEN TRINITY COLLEGE D02 CX56 DUBLIN 2 See on map Region Ireland Eastern and Midland Dublin Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 99 000,00 SIEC BADAWCZA LUKASIEWICZ - INSTYTUT FARMACEUTYCZNY Participation ended Poland Net EU contribution € 131 535,00 Address UL. RYDYGIERA 8 01 793 Warszawa See on map Region Makroregion województwo mazowieckie Warszawski stołeczny Miasto Warszawa Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 131 535,00 PHYSIOLUTION GMBH Germany Net EU contribution € 45 000,00 Address WALTHER-RATHENAU-STRASSE 49 A 17489 Greifswald See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 45 000,00 APPLIED PROCESS COMPANY LIMITED Ireland Net EU contribution € 4 500,00 Address BUILDING 11 CHERRYWOOD BUSINESS PARK LOUGHLINSTOWN D18DH50 Dublin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 4 500,00 HELSINGIN YLIOPISTO Finland Net EU contribution € 139 500,00 Address YLIOPISTONKATU 3 00014 Helsingin Yliopisto See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 139 500,00 ZENTIVA, K.S. Czechia Net EU contribution € 332 100,00 Address U KABELOVNY 130 10237 Prague See on map Region Česko Praha Hlavní město Praha Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 332 100,00 POLITECHNIKA POZNANSKA Poland Net EU contribution € 319 500,00 Address PL MARII SKLODOWSKIEJ CURIE 5 60-965 POZNAN See on map Region Makroregion północno-zachodni Wielkopolskie Miasto Poznań Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 319 500,00 UNIVERZA V LJUBLJANI Slovenia Net EU contribution € 135 000,00 Address KONGRESNI TRG 12 1000 Ljubljana See on map Region Slovenija Zahodna Slovenija Osrednjeslovenska Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 135 000,00 VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE Czechia Net EU contribution € 94 500,00 Address TECHNICKA 5 166 28 Praha See on map Region Česko Praha Hlavní město Praha Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 94 500,00 CELON PHARMA SA Poland Net EU contribution € 40 500,00 Address ULICA OGRODOWA 2A 05 092 KIELPIN See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 40 500,00 Partners (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY United States Net EU contribution € 0,00 Address RUTGERS PLAZA 3 08901 New Brunswick See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSITY OF CENTRAL FLORIDA United States Net EU contribution € 0,00 Address CENTRAL FLORIDA BLVD 4000 32816 Orlando See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data
