The research activities were focused on the investigations and the developments of natural materials which can be applied under the use of Tissue Engineering and Regenerative Medicine (TERM) based procedures. Following this main object, the work was performed as follows:
• The natural biomaterials were selected and processed by using different processing methodologies.
• The fabrications TREM bioactive scaffolds with defined biological and physical properties were made based on the selected materials.
• Protocols and standard procedures were defined and optimized for material processing and characterizations, scaffold fabrications, in vitro evaluations of the materials and scaffolds.
• The investigations on the effects of the scaffolds built by different materials on the differentiation of stem cells using different progenitor cells and considering tailored possible applications.
At the end of the project, 7 natural materials were selected, 16 blends were prepared and tested, 25 protocols and procedures were defined for material processing, scaffold fabrication and in vitro evaluations, and 10 3D- in vitro models were selected and tested. 16 papers were published under the project and 2 patents were proved and 1 patent is under preparation.
During the project, winter/summer schools, workshops, and seminars were organized by the consortium and more than 150 researchers were trained. 56 secondments were implemented, including 17 mobilities of PhD students and young researchers. This exchange provided opportunities to build their future careers, especially for whom came from Asia to Europe. The collaborations within the consortium also extended involving third parties, including other universities and research institutions.
The strategies developed by REMIX led to the development of new projects with the local governments and nations and a new Horizon 2020 project. The scientific results of the project were diffused to the scientific community and also to the general public, by presenting in public events, TV, seminars, lectures, workshops, and conferences. The knowledge developed during the project also brought new collaborations with companies, which showed potential translations to industries and the market.
