A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis

Project Information

LeiSHield-MATI

Grant agreement ID: 778298

DOI

10.3030/778298

Project closed

EC signature date 16 November 2017

Start date 1 April 2018

End date 30 September 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 1 750 500,00

EU contribution

€ 1 750 500,00

Coordinated by

INSTITUT PASTEUR
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (2)

Kick-off meeting, a booklet compiling project documentation provided to all partners, a web-based project management platform accessible through the LeiSHield-MATI website

Kickoff meeting a booklet compiling project documentation provided to all partners a webbased project management platform accessible through the LeiSHieldMATI website

Symposium highlighting the achievements from LeiSHield-MATI

Symposium highlighting the achievements from LeiSHieldMATI

Publications

Peer reviewed articles (20)

Biomarkers of Cutaneous Leishmaniasis.

Author(s): Fariborz Bahrami; Ali M. Harandi; Sima Rafati
Published in: Frontiers in Cellular and Infection Microbiology, Issue 22352988, 2018, ISSN 2235-2988
Publisher: Frontiers Media S. A.
DOI: 10.3389/fcimb.2018.00222

Genetic Diversity and Population Structure of Leishmania infantum in Morocco as Revealed by Multilocus Sequence Typing (MLST) Approach

Author(s): Sara El Mazini, Mourad Barhoumi , Idris Mhaidi , Othmane Daoui , Mouad Ait Kbaich , Sofia El Kacem , Imane El Idrissi Saik , Myriam Riyad , Khadija Bekhti , Ikram Guizani , Meryem Lemrani 
Published in: Pathogens, 2023, ISSN 2076-0817
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens12060785

Isolation, characterization, and functional study of extracellular vesicles derived from Leishmania tarentolae

Author(s): M Shokouhy; H Sarvnaz; Y Taslimi; MS Lajevardi; S Habibzadeh; A Mizbani; F Shekari; M Behbahani; AC Torrecilhas; S Rafati
Published in: Frontiers in Cellular and Infection Microbiology, 2022, ISSN 2235-2988
Publisher: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.921410

Phlebotomine sand flies (Diptera: Psychodidae) of the Maghreb region: A systematic review of distribution, morphology, and role in the transmission of the pathogens.

Author(s): Benallal KE, Garni R, Harrat Z, Volf P, Dvorak V.
Published in: PLoS Neglected Tropical Diseases, 2022, ISSN 1935-2727
Publisher: Public Library of Science
DOI: 10.1371/journal.pntd.0009952

The LeiSHield-MATI consortium: An international project to understand and combat cutaneous leishmaniasis through research and innovation staff exchange

Author(s): Fariborz Bahrami; Sima Rafati
Published in: Journal of Medical Microbiology and Infectious Diseases, Vol 7, Iss 3, Pp 85-86 (2019), Issue 23455349, 2019, ISSN 2345-5349
Publisher: Journal of medical microbiology and infectious diseases
DOI: 10.29252/jommid.7.3.85

Experimental evolution links post-transcriptional regulation to Leishmania fitness gain

Author(s): Laura Piel; K. Shanmugha Rajan; Giovanni Bussotti; Hugo Varet; Rachel Legendre; Caroline Proux; Thibaut Douché; Quentin Giai-Gianetto; Thibault Chaze; Thomas Cokelaer; Barbora Vojtkova; Nadav Gordon-Bar; Tirza Doniger; Smadar Cohen-Chalamish; Praveenkumar Rengaraj; Céline Besse; Anne Boland; Jovana Sadlova; Jean-François Deleuze; Mariette Matondo; Ron Unger; Petr Volf; Shulamit Michaeli; Pascal
Published in: PLoS Pathogens, Issue 15537366, 2022, ISSN 1553-7366
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1010375

Th1 concomitant immune response mediated by IFN-γ protects against sand fly delivered Leishmania infection: Implications for vaccine design

Author(s): Negar Seyed,Sima Rafati
Published in: Cytokine, Issue 7,4, 2021, ISSN 1043-4666
Publisher: Academic Press
DOI: 10.1016/j.cyto.2020.155247

Leishmania tarentolae as Potential Live Vaccine Co-Expressing Distinct Salivary Gland Proteins Against Experimental Cutaneous Leishmaniasis in BALB/c Mice Model

Author(s): MS Lajevardi; E Gholami; T Taheri; H Sarvnaz; S Habibzadeh; N Seyed; Y Mortazavi; S Rafati
Published in: Frontiers in Immunology, 2022, ISSN 2235-2988
Publisher: Frontiers Media S. A.
DOI: 10.3389/fimmu.2022.895234

Cutaneous Leishmaniasis in Algeria; Highlight on the Focus of M’Sila

Author(s): Benikhlef, Razika; Aoun, Karim; Boudrissa, Abdelkarim; Ben Abid, Meriem; Cherif, Kamel; Aissi, Wafa; Benrekta, Souad; Boubidi, Said C.; Späth, Gerald F.; Bouratbine, Aïda; Sereno, Denis; Harrat, Zoubir
Published in: Microorganisms, 2021, 9, 962, Issue 20762607, 2022, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms9050962

Host competence of Algerian Gerbillus amoenus for Leishmania major. 

Author(s): Benallal KE, Mezai G, Mefissel M, Klari N, Lardjane C, Khardine AF, Kherachi I, Dib Y, Brahmi K, Sadlova J, Volf P, Harrat Z.
Published in: International Journal for Parasitology: Parasites and Wildlife, 2023, ISSN 2213-2244
Publisher: Elsevier BV
DOI: 10.1016/j.ijppaw.2023.04.007

Profiling inflammatory response in lesions of cutaneous leishmaniasis patients using a non-invasive sampling method combined with a high-throughput protein detection assay

Author(s): Yasaman Taslimi; Christopher Agbajogu; Siggeir F. Brynjolfsson; Nasrin Masoudzadeh; Vahid Mashayekhi; Safoora Gharibzadeh; Malin Östensson; Sravya Sowdamini Nakka; Amir Mizbani; Sima Rafati; Ali M. Harandi; Ali M. Harandi
Published in: Cytokine, 2020, ISSN 1043-4666
Publisher: Academic Press
DOI: 10.1016/j.cyto.2020.155056

Molecular signatures of anthroponotic cutaneous leishmaniasis in the lesions of patients infected with Leishmania tropica

Author(s): Nasrin Masoudzadeh; Malin Östensson; Josefine Persson; Vahid Mashayekhi Goyonlo; Christopher Agbajogu; Yasaman Taslimi; Reza Erfanian Salim; Farnaz Zahedifard; Amir Mizbani; Housein Malekafzali Ardekani; Bronwyn M. Gunn; Bronwyn M. Gunn; Sima Rafati; Ali M. Harandi; Ali M. Harandi
Published in: Scientific Reports,, 2020, Page(s) Vol 10, Iss 1, Pp 1-15, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-72671-7

Genome instability drives epistatic adaptation in the human pathogen Leishmania

Author(s): Giovanni Bussotti; Laura Piel; Pascale Pescher; Malgorzata A. Domagalska; K. Shanmugha Rajan; Smadar Cohen-Chalamish; Tirza Doniger; Disha-Gajanan Hiregange; Peter J Myler; Ron Unger; Shulamit Michaeli; Gerald F. Späth
Published in: "Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2021, 118 (51), pp.e2113744118. ⟨10.1073/pnas.2113744118⟩", Issue 00278424, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2113744118

Blood transcriptional profiles distinguish different clinical stages of cutaneous leishmaniasis in humans

Author(s): Fariborz Bahrami , Nasrin Masoudzadeh , Suzanne Van Veen , Josefine Persson ,Arezou Lari , Hamzeh Sarvnaz , Yasaman Taslimi , Malin Östensson , Björn Andersson ,Iraj Sharifi , Vahid Mashayekhi Goyonlo , Tom HM Ottenhoff , Mariëlle C. Haks ,Ali M. Harandi , Sima Rafati
Published in: Molecular Immunology, 2022, Page(s) Pages 165-173, ISSN 2213-2244
Publisher: Elsevier BV
DOI: 10.1016/j.molimm.2022.07.008

Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage

Author(s): Giovanni Bussotti , Blaise Li , Pascale Pescher , Barbora Vojtkova, Isabelle Louradour, Katerina Pruzinova , Jovana Sadlova , Petr Volf, and Gerald F. Späth
Published in: The Proceedings of the National Academy of Sciences (PNAS), Issue 5, 2023, Page(s) Vol. 120- No. 10, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2220828120

First Report of Two Jaculus Rodents as Potential Reservoir Hosts of Leishmania Parasites in Tunisia.

Author(s): Ghawar W, Chaouch M, Ben Salah A, Snoussi MA, Salem S, Kharroubi G, Chouchen S, Bouaoun A, Laouini D, Bettaieb J, Ben Abderrazak S.
Published in: Microorganisms, 2022, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms10081502

GIP: An open-source computational pipeline for mapping genomic instability from protists to cancer cells

Author(s): G. F. Spaeth; Giovanni Bussotti
Published in: "Nucleic Acids Research, Oxford University Press, 2021, ⟨10.1093/nar/gkab1237⟩", Issue 03051048, 2022, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1101/2021.06.15.448580

Infectiousness of Asymptomatic Meriones shawi, Reservoir Host of Leishmania major.

Author(s): Sadlova J, Vojtkova B, Lestinova T, Becvar T, Frynta D, Benallal KE, Mekarnia N, Harrat Z, Volf P
Published in: Pathogens, 2023, ISSN 2076-0817
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens12040614

Tape-Disc-Loop-mediated Isothermal Amplification (TD-LAMP) Method as noninvasive approach for Diagnosis of Cutaneous Leishmaniasis caused by L. tropica

Author(s): Yasaman Taslimi; Sima Habibzadeh; Vahid Mashayekhi Goyonlo; Amin Akbarzadeh; Zahra Azarpour; Safoora Gharibzadeh; Mehrdad Shokouhy; Josefine Persson; Amir Mizbani; Sima Rafati; Ali M. Harandi
Published in: Heliyon Microbiology, 2023, ISSN 1097-4172
Publisher: Cell Press
DOI: 10.1016/j.heliyon.2023.e21397

Identification of blood source preferences and Leishmania infection in sand flies (Diptera: Psychodidae) in north-eastern Algeria.

Author(s): Messahel NE, Benallal KE, Halada P, Lafri I, Manseur H, Hakem A, Houali K, Harrat Z, Volf P, Dvorak V.
Published in: Veterinary Parasitology: Regional Studies and Reports, 2022, ISSN 2213-2244
Publisher: Elsevier BV
DOI: 10.1016/j.vprsr.2022.100729