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SFICAM: Ultrafast Fiber-Based Single-Photon Camera for Advanced Microscopy

Objective

Light microscopy is critical to many fields, from biology and medicine to technology development and industry. One important breakthrough that enabled the development of super-resolution microscopy was the development of enhanced cameras capable of recording low light-level images with single-photon sensitivity. However such gain in spatial resolution is compromised by low temporal resolution, since these cameras work at video rate or somewhat faster, while many applications require to characterize dynamics which could be a million times faster.
We propose here a proof of concept demonstration of a technique that enhances the resolution of optical microscopy in both space and time by significantly enhancing camera frame rates while still retaining single-photon sensitivity.
Our approach is to form a single-photon sensitive camera using an array of fibres to guide light into single-photon detectors. In this proof-of-concept of a Single-Photon Fibre-optics Camera (SFICAM), we shall demonstrate a device that could resolve light emitters spatially with nanometric resolution and temporally with nsec precision. We argue that even with
a limited number of elements, and therefore with a small frame size, such cameras could be effective, by combining them with scanning laser microscopy techniques. In the course of this POC project we shall expand the small SFICAM already constructed during the project QUAMI using either individual single photon detectors or monolithic arrays of detectors, and demonstrate its utility and advantage in several microscope modalities. We shall also pursue IP protection of our device and proactively search for industrial partners that will advance it to market.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2017-PoC

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Host institution

WEIZMANN INSTITUTE OF SCIENCE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Address
HERZL STREET 234
7610001 Rehovot
Israel

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 150 000,00

Beneficiaries (1)

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