Steady-state and demand-driven dendritic cell generation

Project Information

DCPOIESIS

Grant agreement ID: 786674

DOI

10.3030/786674

Project closed

EC signature date 25 May 2018

Start date 1 September 2018

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

THE FRANCIS CRICK INSTITUTE LIMITED
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

An isoform of Dicer protects mammalian stem cells against multiple RNA viruses

Author(s): Enzo Z. Poirier, Michael D. Buck, Probir Chakravarty, Joana Carvalho, Bruno Frederico, Ana Cardoso, Lyn Healy, Rachel Ulferts, Rupert Beale, Caetano Reis e Sousa
Published in: Science, Issue 373/6551, 2021, Page(s) 231-236, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abg2264

Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

Author(s): Evangelos Giampazolias, Oliver Schulz, Kok Haw Jonathan Lim, Neil C. Rogers, Probir Chakravarty, Naren Srinivasan, Oliver Gordon, Ana Cardoso, Michael D. Buck, Enzo Z. Poirier, Johnathan Canton, Santiago Zelenay, Stefano Sammicheli, Natalia Moncaut, Sunita Varsani-Brown, Ian Rosewell, Caetano Reis e Sousa
Published in: Cell, Issue 184/15, 2021, Page(s) 4016-4031.e22, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.05.021

Distinct ontogenetic lineages dictate cDC2 heterogeneity

Author(s): Carlos M. Minutti, Cécile Piot, Mariana Pereira da Costa, Probir Chakravarty, Neil Rogers, Hector Huerga Encabo, Ana Cardoso, Jane Loong, Gilles Bessou, Cyrille Mionnet, Jean Langhorne, Dominique Bonnet, Marc Dalod, Elena Tomasello, Caetano Reis e Sousa
Published in: Nature Immunology, Issue 25, 2024, Page(s) 448-461, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-024-01745-9

Dendritic Cells Revisited

Author(s): Mar Cabeza-Cabrerizo, Ana Cardoso, Carlos M. Minutti, Mariana Pereira da Costa, Caetano Reis e Sousa
Published in: Annual Review of Immunology, Issue 39/1, 2021, ISSN 0732-0582
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-immunol-061020-053707

The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens

Author(s): Johnathan Canton, Hanna Blees, Conor M. Henry, Michael D. Buck, Oliver Schulz, Neil C. Rogers, Eleanor Childs, Santiago Zelenay, Hefin Rhys, Marie-Charlotte Domart, Lucy Collinson, Andres Alloatti, Cara J. Ellison, Sebastian Amigorena, Venizelos Papayannopoulos, David C. Thomas, Felix Randow, Caetano Reis e Sousa
Published in: Nature Immunology, Issue 22/2, 2021, Page(s) 140-153, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-020-00824-x

SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay

Author(s): Michael D. Buck, Enzo Z. Poirier, Ana Cardoso, Bruno Frederico, Johnathan Canton, Sam Barrell, Rupert Beale, Richard Byrne, Simon Caidan, Margaret Crawford, Laura Cubitt, Sonia Gandhi, Robert Goldstone, Paul R. Grant, Kiran Gulati, Steve Hindmarsh, Michael Howell, Michael Hubank, Rachael Instrell, Ming Jiang, George Kassiotis, Wei-Ting Lu, James I. MacRae, Iana Martini, Davin Miller, David Moore,
Published in: Wellcome Open Research, Issue 6, 2021, Page(s) 9, ISSN 2398-502X
Publisher: Wellcome Trust
DOI: 10.12688/wellcomeopenres.16517.2

Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity

Author(s): Mar Cabeza-Cabrerizo, Carlos M. Minutti, Mariana Pereira da Costa, Ana Cardoso, Robert P. Jenkins, Justina Kulikauskaite, Michael D. Buck, Cécile Piot, Neil Rogers, Stefania Crotta, Lynne Whittaker, Hector Huerga Encabo, John W. McCauley, Judith E. Allen, Manolis Pasparakis, Andreas Wack, Erik Sahai, Caetano Reis e Sousa
Published in: Science Immunology, Issue 6/65, 2021, ISSN 2470-9468
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.abi9331

DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential

Author(s): Bruno Frederico, Isaura Martins, Diana Chapela, Francesca Gasparrini, Probir Chakravarty, Tobias Ackels, Cécile Piot, Bruna Almeida, Joana Carvalho, Alessandro Ciccarelli, Christopher J. Peddie, Neil Rogers, James Briscoe, François Guillemot, Andreas T. Schaefer, Leonor Saúde, Caetano Reis e Sousa
Published in: Developmental Cell, Issue 57, 2024, Page(s) 1957-1975.e9, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2022.07.012

Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors

Author(s): Mar Cabeza-Cabrerizo, Janneke van Blijswijk, Stephan Wienert, Daniel Heim, Robert P. Jenkins, Probir Chakravarty, Neil Rogers, Bruno Frederico, Sophie Acton, Evelyne Beerling, Jacco van Rheenen, Hans Clevers, Barbara U. Schraml, Marc Bajénoff, Michael Gerner, Ronald N. Germain, Erik Sahai, Frederick Klauschen, Caetano Reis e Sousa
Published in: Science Immunology, Issue 4/33, 2019, Page(s) eaaw1941, ISSN 2470-9468
Publisher: Science Immunology
DOI: 10.1126/sciimmunol.aaw1941

Slicing and dicing viruses: antiviral RNA interference in mammals

Author(s): Pierre V Maillard, Annemarthe G Veen, Enzo Z Poirier, Caetano Reis e Sousa
Published in: The EMBO Journal, Issue 38/8, 2019, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2018100941

Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors

Author(s): Mariana Pereira da Costa, Carlos M. Minutti, Cécile Piot, Evangelos Giampazolias, Ana Cardoso, Mar Cabeza-Cabrerizo, Neil C. Rogers, Marta Lebrusant-Fernandez, Chrysante S. Iliakis, Andreas Wack, Caetano Reis e Sousa
Published in: Cell Reports, Issue 42, 2024, Page(s) 112881, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.112881

Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation

Author(s): Eleanor Childs, Conor M. Henry, Johnathan Canton, Caetano Reis e Sousa
Published in: Open Biology, Issue 11/11, 2021, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.210194