GENetics and the Electrocardiogram for predicting Scd rISk

Información del proyecto

GENESIS

Identificador del acuerdo de subvención: 786833

DOI

10.3030/786833

Proyecto cerrado

Fecha de la firma de la CE 19 Marzo 2018

Fecha de inicio 18 Marzo 2019

Fecha de finalización 17 Marzo 2021

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 183 454,80

Aportación de la UE

€ 183 454,80

Coordinado por

QUEEN MARY UNIVERSITY OF LONDON
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Conference proceedings (9)

Sex Differences in the Morphology of RR-Matched T-waves

Autores: Julia Ramírez, Stefan van Duijvenboden, Andrew Tinker, Pier Lambiase, Patricia Munroe, Michele Orini
Publicado en: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2020.402

Interaction Between ECG and Genetic Markers of Coronary Artery Disease

Autores: Julia Ramírez, Stefan van Duijvenboden, William Young, Andrew Tinker, Pier Lambiase, Patricia Munroe, Michele Orini
Publicado en: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2020.478

Data Augmentation for Heart Arrhythmia Classification

Autores: Mercedeh J. Rezaei, John R. Woodward, Julia Ramirez, Patricia Munroe
Publicado en: 2020 IEEE 32nd International Conference on Tools with Artificial Intelligence (ICTAI), 2020, Página(s) 929-934, ISBN 978-1-7281-9228-4
Editor: IEEE
DOI: 10.1109/ictai50040.2020.00145

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels

Autores: Syed Hassaan Ahmed Bukhari, Flavio Palmieri, Dina Ferreira, Mark Potse, Julia Ramırez, Pablo Laguna, Carlos Sanchez, Esther Pueyo
Publicado en: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2019.404

Evaluating the Impact of Physiological Variability in Genome-Wide Association Studies of Resting Heart Rate

Autores: Stefan van Duijvenboden, Julia Ramírez, William J. Young, Andrew Tinker, Patricia B. Munroe, Pier D. Lambiase, Michele Orini
Publicado en: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2020.483

T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients

Autores: Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Beatriz Bergasa, Ferreira Dina, Alba Martin, Syed Hassaan Ahamed, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna
Publicado en: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2019.109

Will Genetic Data Significantly Change Cardiovascular Risk Prediction in Daily Practice?

Autores: William Young, Julia Ramírez, Stefan van Duijvenboden, Andrew Tinker, Pier Lambiase, Patricia Munroe, Michele Orini
Publicado en: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2020.481

Genetic Architecture of Quantitative Cardiovascular Traits: Blood Pressure, ECG and Imaging Phenotypes

Autores: Nay Aung, William Young, Stefan Van Duijvenboden, Julia Ramírez, Steffen Petersen, Patricia Munroe
Publicado en: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2020.477

Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic versus Principal Component Analysis

Autores: Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martin, Esther Pueyo, Pablo Laguna, Juan Pablo Martínez, Julia Ramírez
Publicado en: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Editor: Computing in Cardiology
DOI: 10.22489/cinc.2020.199

Peer reviewed articles (14)

Genetically-Determined Serum Calcium Levels and Markers of Ventricular Repolarisation: A Mendelian Randomization Study in the UK Biobank

Autores: William J. Young, Helen R. Warren, Dennis O. Mook-Kanamori, Julia Ramírez, Stefan van Duijvenboden, Michele Orini, Andrew Tinker, Diana van Heemst, Pier D. Lambiase, J. Wouter Jukema, Patricia B. Munroe, Raymond Noordam
Publicado en: Circulation: Genomic and Precision Medicine, 2021, ISSN 2574-8300
Editor: American Heart Association Journals
DOI: 10.1161/circgen.120.003231

Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate

Autores: Hassaan A. Bukhari, Flavio Palmieri, Julia Ramirez, Pablo Laguna, Jose Esteban Ruiz, Dina Ferreira, Mark Potse, Carlos Sanchez, Esther Pueyo
Publicado en: IEEE Transactions on Biomedical Engineering, 2020, Página(s) 1-1, ISSN 0018-9294
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2020.3043844

Ventricular Restitution Predicts Paroxysmal Atrial Fibrillation in Horses

Autores: Julia Ramírez, Andrew Tinker
Publicado en: Function, Edición 2/1, 2020, ISSN 2633-8823
Editor: Oxford Academic
DOI: 10.1093/function/zqaa038

Monitoring blood potassium concentration in hemodialysis patients by quantifying T-wave morphology dynamics

Autores: Flavio Palmieri, Pedro Gomis, Dina Ferreira, José Esteban Ruiz, Beatriz Bergasa, Alba Martín-Yebra, Hassaan A. Bukhari, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna
Publicado en: Scientific Reports, Edición 11/1, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-82935-5

The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank

Autores: Judit García-González, Julia Ramírez, David M. Howard, Caroline H. Brennan, Patricia B. Munroe, Robert Keers
Publicado en: Translational Psychiatry, Edición 10/1, 2020, ISSN 2158-3188
Editor: Nature Publishing Group
DOI: 10.1038/s41398-020-01009-8

Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics

Autores: Julia Ramírez, Stefan van Duijvenboden, Nay Aung, Pablo Laguna, Esther Pueyo, Andrew Tinker, Pier D. Lambiase, Michele Orini, Patricia B. Munroe
Publicado en: Circulation: Arrhythmia and Electrophysiology, Edición 12/10, 2019, ISSN 1941-3149
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circep.119.007549

Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation

Autores: Lu-Chen Weng, Amelia Weber Hall, Seung Hoan Choi, Sean J. Jurgens, Jeffrey Haessler, Nathan A. Bihlmeyer, Niels Grarup, Honghuang Lin, Alexander Teumer, Ruifang Li-Gao, Jie Yao, Xiuqing Guo, Jennifer A. Brody, Martina Müller-Nurasyid, Katharina Schramm, Niek Verweij, Marten E. van den Berg, Jessica van Setten, Aaron Isaacs, Julia Ramírez, Helen R. Warren, Sandosh Padmanabhan, Jan A. Kors, Rudolf
Publicado en: Circulation: Genomic and Precision Medicine, Edición 13/5, 2020, Página(s) 387-395, ISSN 2574-8300
Editor: AHA Journals
DOI: 10.1161/circgen.119.002874

Resting Heart Rate and Type 2 Diabetes

Autores: Patricia B. Munroe, Julia Ramírez, Stefan van Duijvenboden
Publicado en: Journal of the American College of Cardiology, Edición 74/17, 2019, Página(s) 2175-2177, ISSN 0735-1097
Editor: Elsevier BV
DOI: 10.1016/j.jacc.2019.08.1030

No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis

Autores: Josephine Mensah-Kane, Amand F. Schmidt, Aroon D. Hingorani, Chris Finan, Yutang Chen, Stefan van Duijvenboden, Michele Orini, Pier D. Lambiase, Andrew Tinker, Eirini Marouli, Patricia B. Munroe, Julia Ramírez
Publicado en: Frontiers in Genetics, Edición 12, 2021, ISSN 1664-8021
Editor: Frontiers Media
DOI: 10.3389/fgene.2021.569323

Nonlinear T-Wave Time Warping-Based Sensing Model for Non-Invasive Personalised Blood Potassium Monitoring in Hemodialysis Patients: A Pilot Study

Autores: Flavio Palmieri, Pedro Gomis, José Ruiz, Dina Ferreira, Alba Martín-Yebra, Esther Pueyo, Juan Martínez, Julia Ramírez, Pablo Laguna
Publicado en: Sensors, Edición 21/8, 2021, Página(s) 2710, ISSN 1424-8220
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s21082710

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

Autores: Ioanna Ntalla, Lu-Chen Weng, James H. Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Nathan R. Tucker, Seung Hoan Choi, Mark D. Chaffin, Carolina Roselli, Michael R. Barnes, Borbala Mifsud, Helen R. Warren, Caroline Hayward, Jonathan Marten, James J. Cranley, Maria Pina Concas, Paolo Gasparini, Thibaud Boutin, Ivana Kolcic, Ozren Polasek, Igor Rudan, Nathalia M. Araujo, Maria Fernanda Lima-
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-15706-x

Genetic Basis and Prognostic Value of Exercise QT Dynamics

Autores: Stefan van Duijvenboden, Julia Ramírez, William J. Young, Borbala Mifsud, Michele Orini, Andrew Tinker, Patricia B. Munroe, Pier D. Lambiase
Publicado en: Circulation: Genomic and Precision Medicine, Edición 13/4, 2020, ISSN 2574-8300
Editor: AHA Journals
DOI: 10.1161/circgen.119.002774

A Method to Minimise the Impact of ECG Marker Inaccuracies on the Spatial QRS-T angle: Evaluation on 1,512 Manually Annotated ECGs

Autores: William J. Young, Stefan van Duijvenboden, Julia Ramírez, Aled Jones, Andrew Tinker, Patricia B. Munroe, Pier D. Lambiase, Michele Orini
Publicado en: Biomedical Signal Processing and Control, Edición 64, 2021, Página(s) 102305, ISSN 1746-8094
Editor: Elsevier BV
DOI: 10.1016/j.bspc.2020.102305

Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval

Autores: Julia Ramírez, Stefan van Duijvenboden, William J. Young, Michele Orini, Pier D. Lambiase, Patricia B. Munroe, Andrew Tinker
Publicado en: The American Journal of Human Genetics, Edición 106/6, 2020, Página(s) 764-778, ISSN 0002-9297
Editor: University of Chicago Press
DOI: 10.1016/j.ajhg.2020.04.009