Selective Functionalization of Saturated Hydrocarbons

Project Information

BioMet

Grant agreement ID: 786976

DOI

10.3030/786976

Project closed

EC signature date 8 May 2018

Start date 1 November 2018

End date 31 October 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 375,00

EU contribution

€ 2 499 375,00

Coordinated by

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (26)

Stereospecific nucleophilic substitution at tertiary and quaternary stereocentres

Author(s): Veeranjaneyulu Lanke, Ilan Marek
Published in: Chemical Science, Issue 11/35, 2020, Page(s) 9378-9385, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc02562c

Stereoselective Synthesis of Polysubstituted Spiropentanes

Author(s): Yair Cohen, Dor Toledano, Ilan Marek
Published in: Journal of the American Chemical Society, Issue 144, 2023, Page(s) 16732-16736, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c07370

Selective Terminal Functionalization of Linear Alkanes**

Author(s): Jeffrey Bruffaerts, Inbar Kesten, Keren BuhnikRosenblau, Anthony Cohen, Nurit Edri, Morgan Cormier, Yuanfei Zhang, GuoMing Ho, Itai Massad, Hila HalfonVerner, Yechezkel Kashi, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 62, 2024, Page(s) 62, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202306343

Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization

Author(s): Lucas Segura, Itai Massad, Masamichi Ogasawara, Ilan Marek
Published in: Organic Letters, Issue 23, 2023, Page(s) 9194-9198, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.1c03513

Stereoinvertive S_N1 Through Neighboring Group Participation

Author(s): Rahul Suresh, Noam Orbach, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 63, 2024, Page(s) 63, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202407602

Stereospecific nucleophilic substitution at quaternary carbon stereocenters of cyclopropyl carbinols

Author(s): Xu Chen, Kaushalendra Patel, Ilan Marek
Published in: Chem, Issue 9, 2024, Page(s) 266-279, ISSN 2451-9294
Publisher: Chem
DOI: 10.1016/j.chempr.2023.01.001

Preparation of Distant Quaternary Carbon Stereocenters by Double Selective RingOpening of 1,1Biscyclopropyl Methanol Derivatives

Author(s): Yogesh Siddaraju, Juliette Sabbatani, Anthony Cohen, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 61, 2023, Page(s) 61, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202203652

Regio- and Diastereoselective Carbometalation Reaction of Cyclopropenes

Author(s): Yair Cohen, Ilan Marek
Published in: Accounts of Chemical Research, Issue 55, 2023, Page(s) 2848-2868, ISSN 0001-4842
Publisher: American Chemical Society
DOI: 10.1021/acs.accounts.2c00424

Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters

Author(s): Xu Chen, Kaushalendra Patel, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 62, 2023, Page(s) 62, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202212425

Stereospecific Reactions Leading to Allylboronic Esters Within Acyclic Systems Bearing Distant Stereocenters

Author(s): David Pierrot, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 59/46, 2020, Page(s) 20434-20438, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202010135

Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes

Author(s): Longyang Dian, Ilan Marek
Published in: ACS Catalysis, Issue 10/2, 2019, Page(s) 1289-1293, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.9b04960

Diastereo- and enantioselective preparation of cyclopropanol derivatives

Author(s): Marwan Simaan, Ilan Marek
Published in: Beilstein Journal of Organic Chemistry, Issue 15, 2019, Page(s) 752-760, ISSN 1860-5397
Publisher: Beilstein-Institut
DOI: 10.3762/bjoc.15.71

Diastereoselective ring opening of fully-substituted cyclopropanes via intramolecular Friedel–Crafts alkylation

Author(s): Veeranjaneyulu Lanke, Fa-Guang Zhang, Alexander Kaushansky, Ilan Marek
Published in: Chemical Science, Issue 10/41, 2019, Page(s) 9548-9554, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc03832a

Highly E -Selective, Stereoconvergent Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling of Alkenyl Ethers

Author(s): Guo-Ming Ho, Heiko Sommer, Ilan Marek
Published in: Organic Letters, Issue 21/8, 2019, Page(s) 2913-2917, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.9b00946

Ru-catalyzed isomerization of ω-alkenylboronates towards stereoselective synthesis of vinylboronates with subsequent in situ functionalization

Author(s): Guo-Ming Ho, Lucas Segura, Ilan Marek
Published in: Chemical Science, 2020, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc02542a

Alkene Isomerization through Allylmetals as a Strategic Tool in Stereoselective Synthesis

Author(s): Itai Massad, Ilan Marek
Published in: ACS Catalysis, Issue 10/10, 2020, Page(s) 5793-5804, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.0c01174

Synthesis of Enantioenriched Vicinal Tertiary and Quaternary Carbon Stereogenic Centers within an Acyclic Chain

Author(s): David Pierrot, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 59/1, 2020, Page(s) 36-49, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201903188

A Tandem Iridium-Catalyzed “Chain-Walking”/Cope Rearrangement Sequence

Author(s): Heiko Sommer, Tal Weissbrod, Ilan Marek
Published in: ACS Catalysis, Issue 9/3, 2019, Page(s) 2400-2406, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.9b00118

Stereoselective Preparation of Distant Stereocenters (1,5) within Acyclic Molecules

Author(s): Anthony Cohen, Jean Chagneau, Ilan Marek
Published in: ACS Catalysis, 2020, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.0c01762

Mechanistic Insights on the Selectivity of the Tandem HeckRing-Opening of Cyclopropyldiol Derivatives

Author(s): Anthony Cohen, Alexander Kaushansky, Ilan Marek
Published in: JACS Au, Issue 2, 2023, Page(s) 687-696, ISSN 2691-3704
Publisher: JACS
DOI: 10.1021/jacsau.1c00547

Publisher Correction: Stereoselective synthesis through remote functionalization

Author(s): Itai Massad, Rahul Suresh, Lucas Segura, Ilan Marek
Published in: Nature Synthesis, Issue 1, 2022, Page(s) 407-407, ISSN 2731-0582
Publisher: nature
DOI: 10.1038/s44160-022-00078-5

Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters

Author(s): Kaushalendra Patel, Veeranjaneyulu Lanke, Ilan Marek
Published in: Journal of the American Chemical Society, Issue 144, 2023, Page(s) 7066-7071, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c01695

Alkene Isomerization Revitalizes the Coates–Claisen Rearrangement

Author(s): Itai Massad ,Prof. Ilan Marek
Published in: Alkene Isomerization Revitalizes the Coates–Claisen Rearrangement, 2021, Page(s) 18509 –18513, ISSN 1521-3757
Publisher: Angewandte
DOI: 10.1002/anie.202105834

Borylated Cyclopropanes as Spring-Loaded Entities: Access to Vicinal Tertiary and Quaternary Carbon Stereocenters in Acyclic Systems

Author(s): Andr U. Augustin, Sergio Di Silvio, Ilan Marek
Published in: Journal of the American Chemical Society, Issue 144, 2023, Page(s) 16298-16302, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c07394

Stereoinvertive Nucleophilic Substitution at Quaternary Carbon Stereocenters of Cyclopropyl Ketones and Ethers

Author(s): Xu Chen, Ilan Marek
Published in: Angewandte Chemie International Edition, Issue 61, 2024, Page(s) 61, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202203673

Highly Diastereoselective Preparation of Tertiary Alkyl Isonitriles by Stereoinvertive Nucleophilic Substitution at a Nonclassical Carbocation

Author(s): Xu Chen, Ilan Marek
Published in: Organic Letters, Issue 25, 2023, Page(s) 2285-2288, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.3c00583