Dynamic mechanisms and functional roles of synaptic plasticity in memory

Project Information

Dyn-Syn-Mem

Grant agreement ID: 787340

DOI

10.3030/787340

Project closed

EC signature date 22 May 2018

Start date 1 February 2019

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 505,00

EU contribution

€ 2 499 505,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (28)

Shifting rules in a brain disorder

Author(s): Daniel Choquet
Published in: Science, Issue 383, 2024, Page(s) 950-951, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adn8707

AMPAR-Dependent Synaptic Plasticity Initiates Cortical Remapping and Adaptive Behaviors during Sensory Experience

Author(s): Tiago Campelo, Elisabete Augusto, Nicolas Chenouard, Aron de Miranda, Vladimir Kouskoff, Come Camus, Daniel Choquet, Frédéric Gambino
Published in: Cell Reports, Issue 32/9, 2020, Page(s) 108097, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.108097

AMPA receptor diffusional trapping machinery as an early therapeutic target in neurodegenerative and neuropsychiatric disorders

Author(s): Daniel Choquet, Patricio Opazo, Hongyu Zhang
Published in: Translational Neurodegeneration, Issue 14, 2025, ISSN 2047-9158
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/s40035-025-00470-z

Advanced imaging and labelling methods to decipher brain cell organization and function

Author(s): Daniel Choquet, Matthieu Sainlos, Jean-Baptiste Sibarita
Published in: Nature Reviews Neuroscience, Issue 22/4, 2021, Page(s) 237-255, ISSN 1471-003X
Publisher: Nature Publishing Group
DOI: 10.1038/s41583-021-00441-z

Regulation of different phases of AMPA receptor intracellular transport by 4.1N and SAP97

Author(s): Caroline Bonnet, Justine Charpentier, Natacha Retailleau, Daniel Choquet, Françoise Coussen
Published in: eLife, Issue 12, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.85609

Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation

Author(s): Luís F. Ribeiro, Tatiana Catarino, Mário Carvalho, Luísa Cortes, Sandra D. Santos, Patricio O. Opazo, Lyn Rosenbrier Ribeiro, Bárbara Oliveiros, Daniel Choquet, José A. Esteban, João Peça, Ana Luísa Carvalho
Published in: Science Signaling, Issue 14/670, 2021, Page(s) eabb1953, ISSN 1937-9145
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scisignal.abb1953

Nanoscale synapse organization and dysfunction in neurodevelopmental disorders

Author(s): Hanna L Zieger, Daniel Choquet
Published in: Neurobiology of Disease, Issue 158, 2021, Page(s) 105453, ISSN 0969-9961
Publisher: Academic Press
DOI: 10.1016/j.nbd.2021.105453

High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning

Author(s): Angela M. Getz, Mathieu Ducros, Christelle Breillat, Aurélie Lampin-Saint-Amaux, Sophie Daburon, Urielle François, Agata Nowacka, Mónica Fernández-Monreal, Eric Hosy, Frédéric Lanore, Hanna L. Zieger, Matthieu Sainlos, Yann Humeau, Daniel Choquet
Published in: Science Advances, Issue 8, 2024, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.abm5298

Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules

Author(s): Charlotte Rimbault, Kashyap Maruthi, Christelle Breillat, Camille Genuer, Sara Crespillo, Virginia Puente-Muñoz, Ingrid Chamma, Isabel Gauthereau, Ségolène Antoine, Coraline Thibaut, Fabienne Wong Jun Tai, Benjamin Dartigues, Dolors Grillo-Bosch, Stéphane Claverol, Christel Poujol, Daniel Choquet, Cameron D. Mackereth, Matthieu Sainlos
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12528-4

Engineering paralog-specific PSD-95 recombinant binders as minimally interfering multimodal probes for advanced imaging techniques

Author(s): Charlotte Rimbault, Christelle Breillat, Benjamin Compans, Estelle Toulmé, Filipe Nunes Vicente, Monica Fernandez-Monreal, Patrice Mascalchi, Camille Genuer, Virginia Puente-Muñoz, Isabel Gauthereau, Eric Hosy, Stéphane Claverol, Gregory Giannone, Ingrid Chamma, Cameron D Mackereth, Christel Poujol, Daniel Choquet, Matthieu Sainlos
Published in: eLife, Issue 13, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.69620

The role of AMPAR lateral diffusion in memory

Author(s): The role of AMPAR lateral diffusion in memory
Published in: Semin Cell Dev Biol 2022, Issue Vol. 125 Pages, 2022, Page(s) 76-83, ISSN 1084-9521
Publisher: Academic Press
DOI: 10.1016/j.semcdb.2022.01.009

CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation

Author(s): Hajer El Oussini, Chun-Lei Zhang, Urielle François, Cecilia Castelli, Aurélie Lampin-Saint-Amaux, Marilyn Lepleux, Pablo Molle, Legeolas Velez, Cyril Dejean, Frederic Lanore, Cyril Herry, Daniel Choquet, Yann Humeau
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-42969-x

Imaging the structural organization of chemical elements in growth cones of developing hippocampal neurons

Author(s): Asuncion Carmona, Si Chen, Florelle Domart, Daniel Choquet, Richard Ortega
Published in: Metallomics, Issue Volume 14, Issue 1, January 2022, mfab073,, 2022, ISSN 1756-591X
Publisher: RSC Publishing
DOI: 10.1093/mtomcs/mfab073

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice

Author(s): Emmanouela Kallergi, Akrivi-Dimitra Daskalaki, Angeliki Kolaxi, Come Camus, Evangelia Ioannou, Valentina Mercaldo, Per Haberkant, Frank Stein, Kyriaki Sidiropoulou, Yannis Dalezios, Mikhail M Savitski, Claudia Bagni, Daniel Choquet, Eric Hosy, Vassiliki Nikoletopoulou
Published in: Nature communication, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28301-z

A super-resolution platform for correlative live single-molecule imaging and STED microscopy

Author(s): V. V. G. Krishna Inavalli, Martin O. Lenz, Corey Butler, Julie Angibaud, Benjamin Compans, Florian Levet, Jan Tønnesen, Olivier Rossier, Gregory Giannone, Olivier Thoumine, Eric Hosy, Daniel Choquet, Jean-Baptiste Sibarita, U. Valentin Nägerl
Published in: Nature Methods, Issue 16/12, 2019, Page(s) 1263-1268, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-019-0611-8

The next generation of approaches to investigate the link between synaptic plasticity and learning

Author(s): Yann Humeau, Daniel Choquet
Published in: Nature Neuroscience, Issue 22/10, 2019, Page(s) 1536-1543, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-019-0480-6

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

Author(s): Benjamin Compans, Come Camus, Emmanouela Kallergi, Silvia Sposini, Magalie Martineau, Corey Butler, Adel Kechkar, Remco V. Klaassen, Natacha Retailleau, Terrence J. Sejnowski, August B. Smit, Jean-Baptiste Sibarita, Thomas M. Bartol, David Perrais, Vassiliki Nikoletopoulou, Daniel Choquet, Eric Hosy
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23133-9

Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids unveils masked epitopes in live neurons.

Author(s): Diogo Bessa-Neto; Gerti Beliu; Alexander Kuhlemann; Valeria Pecoraro; Sören Doose; Natacha Retailleau; Nicolas Chevrier; David Perrais; Markus Sauer; Daniel Choquet
Published in: "Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-27025-w⟩", Issue 1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27025-w

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation

Author(s): Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi
Published in: Nature Neuroscience, Issue 24/6, 2021, Page(s) 777-785, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-021-00843-3

Active image optimization for lattice light sheet microscopy in thick samples

Author(s): Maxime Malivert, Fabrice Harms, Cynthia Veilly, Jerome Legrand, Ziqiang Li, Emmanuelle Bayer, Daniel Choquet, Mathieu Ducros
Published in: Biomedical Optics Express, Issue 13, 2024, Page(s) 6211, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.471757

Molecular mechanisms of AMPAR reversible stabilization at synapses

Author(s): Diogo Bessa-Neto, Daniel Choquet
Published in: Molecular and Cellular Neuroscience, Issue 125, 2024, Page(s) 103856, ISSN 1044-7431
Publisher: Academic Press
DOI: 10.1016/j.mcn.2023.103856

AMPA receptor nanoscale dynamic organization and synaptic plasticities

Author(s): Daniel Choquet, Eric Hosy
Published in: Current Opinion in Neurobiology, Issue 63, 2020, Page(s) 137-145, ISSN 0959-4388
Publisher: Elsevier BV
DOI: 10.1016/j.conb.2020.04.003

Linking glutamate receptor movements and synapse function

Author(s): Laurent Groc, Daniel Choquet
Published in: Science, Issue 368/6496, 2020, Page(s) eaay4631, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aay4631

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

Author(s): Andrea Toledo, Mathieu Letellier, Giorgia Bimbi, Béatrice Tessier, Sophie Daburon, Alexandre Favereaux, Ingrid Chamma, Kristel Vennekens, Jeroen Vanderlinden, Matthieu Sainlos, Joris de Wit, Daniel Choquet, Olivier Thoumine
Published in: elife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.75233

Activity-dependent diffusion trapping of AMPA receptors as a key step for expression of early LTP

Author(s): Agata Nowacka, Angela M. Getz, Diogo Bessa-Neto, Daniel Choquet
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 379, 2024, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2023.0220

Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses

Author(s): Julia Goncalves, Tomas M. Bartol, Côme Camus, Florian Levet, Ana Paula Menegolla, Terrence J. Sejnowski, Jean-Baptiste Sibarita, Michel Vivaudou, Daniel Choquet, Eric Hosy
Published in: Proceedings of the National Academy of Sciences, Issue 117/25, 2020, Page(s) 14503-14511, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1922563117

Correlating STED and synchrotron XRF nano-imaging unveils cosegregation of metals and cytoskeleton proteins in dendrites

Author(s): Florelle Domart, Peter Cloetens, Stéphane Roudeau, Asuncion Carmona, Emeline Verdier, Daniel Choquet, Richard Ortega
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.62334

Functional recruitment of dynamin requires multimeric interactions for efficient endocytosis

Author(s): Morgane Rosendale, Thi Nhu Ngoc Van, Dolors Grillo-Bosch, Silvia Sposini, Léa Claverie, Isabel Gauthereau, Stéphane Claverol, Daniel Choquet, Matthieu Sainlos, David Perrais
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12434-9

Non-peer reviewed articles (1)

Understanding the nervous system: lessons from Frontiers in Neurophotonics

Author(s): Yves De Koninck, Johanna Alonso, Stéphane Bancelin, Jean-Claude Béïque, Erik Bélanger, Catherine Bouchard, Marco Canossa, Johan Chaniot, Daniel Choquet, Marie-Ève Crochetière, Nanke Cui, Lydia Danglot, Paul De Koninck, Anna Devor, Mathieu Ducros, Angela M. Getz, Mohamed Haouat, Iván Coto Hernández, Nate Jowett, Iason Keramidis, Céline Larivière-Loiselle, Flavie Lavoie-Cardinal, Harold D.
Published in: Neurophotonics, Issue 11, 2024, ISSN 2329-423X
Publisher: SPIE-Intl Soc Optical Eng
DOI: 10.1117/1.nph.11.1.014415

Book chapters (1)

Targeting of membrane proteins with fluoronanogold probes for high-resolution correlative microscopy

Author(s): Daniel Choquet, Melina Petrel, Mónica Fernández-Monreal
Published in: Methods in Cell Biology, Correlative Light and Electron Microscopy V, 2024, Page(s) 57-72
Publisher: Elsevier
DOI: 10.1016/bs.mcb.2024.02.035