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Mechanisms to emerge and replicate the first sequence information of life in geothermal microfluidics of early Earth

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tRNA sequences can assemble into a replicator

Author(s): Alexandra Kühnlein, Simon A Lanzmich, Dieter Braun
Published in: eLife, Issue 10, 2021, ISSN 2050-084X
DOI: 10.7554/elife.63431

Kinetic Microscale Thermophoresis for Simultaneous Measurement of Binding Affinity and Kinetics

Author(s): Julian A. C. Stein, Alan Ianeselli, Dieter Braun
Published in: Angewandte Chemie, 2021, ISSN 0044-8249
DOI: 10.1002/ange.202101261

Cooperative Ligation Breaks Sequence Symmetry and Stabilizes Early Molecular Replication

Author(s): Shoichi Toyabe, Dieter Braun
Published in: Physical Review X, Issue 9/1, 2019, ISSN 2160-3308
DOI: 10.1103/physrevx.9.011056

Fission of Lipid-Vesicles by Membrane Phase Transitions in Thermal Convection

Author(s): Patrick W. Kudella, Katharina Preißinger, Matthias Morasch, Christina F. Dirscherl, Dieter Braun, Achim Wixforth, Christoph Westerhausen
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
DOI: 10.1038/s41598-019-55110-0

Periodic Melting of Oligonucleotides by Oscillating Salt Concentrations Triggered by Microscale Water Cycles Inside Heated Rock Pores

Author(s): Alan Ianeselli, Christof B. Mast, Dieter Braun
Published in: Angewandte Chemie, Issue 131/37, 2019, Page(s) 13289-13294, ISSN 0044-8249
DOI: 10.1002/ange.201907909

Continuous nonenzymatic cross-replication of DNA strands with in situ activated DNA oligonucleotides

Author(s): Evgeniia Edeleva, Annalena Salditt, Julian Stamp, Philipp Schwintek, Job Boekhoven, Dieter Braun
Published in: Chemical Science, Issue 10/22, 2019, Page(s) 5807-5814, ISSN 2041-6520
DOI: 10.1039/c9sc00770a

Heated gas bubbles enrich, crystallize, dry, phosphorylate and encapsulate prebiotic molecules

Author(s): Matthias Morasch, Jonathan Liu, Christina F. Dirscherl, Alan Ianeselli, Alexandra Kühnlein, Kristian Le Vay, Philipp Schwintek, Saidul Islam, Mérina K. Corpinot, Bettina Scheu, Donald B. Dingwell, Petra Schwille, Hannes Mutschler, Matthew W. Powner, Christof B. Mast, Dieter Braun
Published in: Nature Chemistry, Issue 11/9, 2019, Page(s) 779-788, ISSN 1755-4330
DOI: 10.1038/s41557-019-0299-5

Thermal Habitat for RNA Amplification and Accumulation

Author(s): Annalena Salditt, Lorenz M. R. Keil, David P. Horning, Christof B. Mast, Gerald F. Joyce, Dieter Braun
Published in: Physical Review Letters, Issue 125/4, 2020, ISSN 0031-9007
DOI: 10.1103/physrevlett.125.048104

CO 2 reduction driven by a pH gradient

Author(s): Reuben Hudson, Ruvan de Graaf, Mari Strandoo Rodin, Aya Ohno, Nick Lane, Shawn E. McGlynn, Yoichi M. A. Yamada, Ryuhei Nakamura, Laura M. Barge, Dieter Braun, Victor Sojo
Published in: Proceedings of the National Academy of Sciences, Issue 117/37, 2020, Page(s) 22873-22879, ISSN 0027-8424
DOI: 10.1073/pnas.2002659117

Structured sequences emerge from random pool when replicated by templated ligation

Author(s): Patrick W. Kudella, Alexei V. Tkachenko, Annalena Salditt, Sergei Maslov, Dieter Braun
Published in: Proceedings of the National Academy of Sciences, Issue 118/8, 2021, Page(s) e2018830118, ISSN 0027-8424
DOI: 10.1073/pnas.2018830118