The eco-evolutionary costs and benefits of CRISPR-Cas systems, and their effect on genome diversity within populations

Project Information

CRISPR-EVOL

Grant agreement ID: 787514

DOI

10.3030/787514

Project closed

EC signature date 17 April 2018

Start date 1 May 2018

End date 30 April 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 495 625,00

EU contribution

€ 2 495 625,00

Coordinated by

TEL AVIV UNIVERSITY
Israel

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Expansion of the global RNA virome reveals diverse clades of bacteriophages

Author(s): Uri Neri, Yuri I. Wolf, Simon Roux, Antonio Pedro Camargo, Benjamin Lee, Darius Kazlauskas, I. Min Chen, Natalia Ivanova, Lisa Zeigler Allen, David Paez-Espino, Donald A. Bryant, Devaki Bhaya, Adrienne B. Narrowe, Alexander J. Probst, Alexander Sczyrba, Annegret Kohler, Armand Séguin, Ashley Shade, Barbara J. Campbell, Björn D. Lindahl, Brandi Kiel Reese, Breanna M. Roque, Chris DeRito, Colin Av
Published in: Cell, 2022, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2022.08.023

Neighboring inteins interfere with one another's homing capacity

Author(s): Israela Turgeman-Grott, Danielle Arsenault, Dekel Yahav, Yutian Feng, Guy Miezner, Doron Naki, Omri Peri, R Thane Papke, Johann Peter Gogarten, Uri Gophna
Published in: PNAS Nexus, Issue 2, 2023, ISSN 2752-6542
Publisher: Oxford University Press (OUP)
DOI: 10.1093/pnasnexus/pgad354

An archaeal Cas3 protein facilitates rapid recovery from DNA damage

Author(s): Guy Miezner, Israela Turgeman-Grott, Kelly M Zatopek, Andrew F Gardner, Leah Reshef, Deepak K Choudhary, Martina Alstetter, Thorsten Allers, Anita Marchfelder, Uri Gophna
Published in: microLife, Issue 4, 2023, ISSN 2633-6693
Publisher: Oxford University Press (OUP)
DOI: 10.1093/femsml/uqad007

A Haloarchaeal Transcriptional Regulator That Represses the Expression of CRISPR-Associated Genes

Author(s): Israela Turgeman-Grott, Yarden Shalev, Netta Shemesh, Rachel Levy, Inbar Eini, Metsada Pasmanik-Chor, Uri Gophna
Published in: Microorganisms, Issue 12, 2024, Page(s) 1772, ISSN 2076-2607
Publisher: MDPI AG
DOI: 10.3390/microorganisms12091772

Pervasive acquisition of CRISPR memory driven by inter-species mating of archaea can limit gene transfer and influence speciation

Author(s): Israela Turgeman-Grott, Shirley Joseph, Sam Marton, Kim Eizenshtein, Adit Naor, Shannon M. Soucy, Aris-Edda Stachler, Yarden Shalev, Mor Zarkor, Leah Reshef, Neta Altman-Price, Anita Marchfelder, Uri Gophna
Published in: Nature Microbiology, Issue 4/1, 2019, Page(s) 177-186, ISSN 2058-5276
Publisher: NPG
DOI: 10.1038/s41564-018-0302-8

Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system

Author(s): A-L. Sailer, J. Brendel, A. Chernev, S. König, T. Bischler, T. Gräfenhan, H. Urlaub, U. Gophna, A. Marchfelder
Published in: Frontiers in Microbiology, Issue 16, 2025, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2025.1543464

Differences in homologous recombination and maintenance of heteropolyploidy between Haloferax volcanii and Haloferax mediterranei

Author(s): Dattani A, Sharon I, Shtifman-Segal E, Robinzon S, Gophna U, Allers T, Altman-Price N.
Published in: G3, 2022, ISSN 2160-1836
Publisher: Genetics Society of America
DOI: 10.1093/g3journal/jkac306