Novel strategies for mammalian cardiac repair

Project Information

CardHeal

Grant agreement ID: 788194

DOI

10.3030/788194

Project closed

EC signature date 17 May 2018

Start date 1 June 2018

End date 31 May 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 268 750,00

EU contribution

€ 2 268 750,00

Coordinated by

WEIZMANN INSTITUTE OF SCIENCE
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion

Author(s): Tamar Eigler, Giulia Zarfati, Emmanuel Amzallag, Sansrity Sinha, Nadav Segev, Yishaia Zabary, Assaf Zaritsky, Avraham Shakked, Kfir-Baruch Umansky, Eyal D Schejter, Douglas P Millay, Eldad Tzahor, Ori Avinoam
Published in: Dev Cell, 2021, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2021.11.022

The small molecule Chicago Sky Blue promotes heart repair following myocardial infarction in mice

Author(s): Oren Yifa, Karen Weisinger, Elad Bassat, Hanjun Li, David Kain, Haim Barr, Noga Kozer, Alexander Genzelinakh, Dana Rajchman, Tamar Eigler, Kfir Baruch Umansky, Daria Lendengolts, Ori Brener, Nenad Bursac, Eldad Tzahor
Published in: JCI Insight, Issue 4/22, 2019, ISSN 2379-3708
Publisher: American Society for Clinical Investigation (ASCI)
DOI: 10.1172/jci.insight.128025

Transient p53-Mediated Regenerative Senescence in the Injured Heart

Author(s): Rachel Sarig, Rachel Rimmer, Elad Bassat, Lingling Zhang, Kfir Baruch Umansky, Daria Lendengolts, Gal Perlmoter, Karina Yaniv, Eldad Tzahor
Published in: Circulation, Issue 139/21, 2019, Page(s) 2491-2494, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.119.040125

ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration.

Author(s): Aharonov A, Shakked A, Umansky KB, Savidor A, Genzelinakh A, Kain D, Lendengolts D, Revach OY, Morikawa Y, Dong J, Levin Y, Geiger B, Martin JF, Tzahor E.
Published in: Nature Cell Biology, 2020, ISSN 1476-4679
Publisher: Springer Nature
DOI: 10.1038/s41556-020-00588-4

Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs

Author(s): Andrea Baehr, Kfir Baruch Umansky, Elad Bassat, Victoria Jurisch, Katharina Klett, Tarik Bozoglu, Nadja Hornaschewitz, Olga Solyanik, David Kain, Bartolo Ferraro, Renee Cohen-Rabi, Markus Krane, Clemens Cyran, Oliver Soehnlein, Karl Ludwig Laugwitz, Rabea Hinkel, Christian Kupatt, Eldad Tzahor
Published in: Circulation, Issue 142/9, 2020, Page(s) 868-881, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.119.045116

Intellectual Property Rights

Patent (2)

TREATMENT OF A HEART DISEASE

Application/Publication number: 19 714487
Date: 2019-03-12
Applicant(s): WEIZMANN INSTITUTE OF SCIENCE

TREATMENT OF AN ISCHEMIC HEART DISEASE

Application/Publication number: 18 826822
Date: 2018-12-03
Applicant(s): WEIZMANN INSTITUTE OF SCIENCE