Intracellular phosphate reception and signaling: A novel homeostatic system with roles for an orphan organelle?

Project Information

INPHORS

Grant agreement ID: 788442

DOI

10.3030/788442

Project closed

EC signature date 25 May 2018

Start date 1 September 2018

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 998,00

EU contribution

€ 2 499 998,00

Coordinated by

UNIVERSITE DE LAUSANNE
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Cryo-EM structure of the polyphosphate polymerase VTC: Coupling polymer synthesis to membrane transit

Author(s): Wei Liu, Jiening Wang, Véronique Comte-Miserez, Mengyu Zhang, Xuejing Yu, Qingfeng Chen, Andreas Mayer*, Shan Wu*, Sheng Ye*
Published in: EMBO Journal, 2023, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2022113320

WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms

Author(s): Maria Giovanna De Leo, Philipp Berger, Andreas Mayer
Published in: Autophagy, 2021, Page(s) 1-27, ISSN 1554-8627
Publisher: Landes Bioscience
DOI: 10.1080/15548627.2021.1886830

Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction

Author(s): Joka Pipercevic1, Bastian Kohl1, Ruta Gerasimaite2,3, Véronique Comte, Sarah Hostachy4, Thomas Müntener1, Elia Agustoni1, Henning Jacob Jessen5, Dorothea Fiedler4, Andreas Mayer2, Sebastian Hiller1*
Published in: Nature Communications, Issue 14, 2023, Page(s) 2645, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-38315-w

CROP: A Retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system

Author(s): Thibault Courtellemont; Maria Giovanna De Leo; Navin Andréw Gopaldass; Andreas Mayer
Published in: EMBO journal, Issue 3, 2022, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.1101/2021.09.06.459059

The chemistry of branched condensed phosphates

Author(s): Tobias Dürr-Mayer1, Danye Qiu 1, Verena B. Eisenbeis 1, Nicole Steck 1, Markus Häner 1, Alexandre Hofer 2, Andreas Mayer, Jay S. Siegel 4,5, Kim K. Baldridge4 & Henning J. Jessen
Published in: Nature Communications, 2021, Page(s) 5368-11, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-25668-3

Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction

Author(s): Navin Gopaldass, Maria Giovanna De Leo, Thibault Courtellemont, Vincent Mercier, Christin Bissig, View ORCID ProfileAurélien Roux, Andreas Mayer
Published in: EMBO Journal, 2023, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2022112287

Phosphate Homeostasis − A Vital Metabolic Equilibrium Maintained Through the INPHORS Signaling Pathway

Author(s): Sisley Austin, Andreas Mayer
Published in: Frontiers in Microbiology, Issue 11, 2020, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2020.01367

Inositol pyrophosphate dynamics reveals control of the yeast phosphate starvation program through 1,5-IP8 and the SPX domain of Pho81

Author(s): Valentin Chabert, Geun-Don Kim, Danye Qiu, Guizhen Liu, Lydie Michaillat Mayer, Muhammed Jamsheer K, Henning J Jessen, Andreas Mayer
Published in: eLife, Issue 12, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.87956.3

Metabolic consequences of polyphosphate synthesis and imminent phosphate limitation

Author(s): Geun-Don Kim, Danye Qiu, Henning Jessen, Andreas Mayer
Published in: mBio, 2023, Page(s) e00102-23, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1101/2022.11.22.517608

Inositol pyrophosphate dynamics in yeast reveals control of the PHO starvation program through 1,5-IP8 and the SPX domain of the CDK inhibitor Pho81

Author(s): Valentin Chabert, Geundon Kim, Danye Qiu, Lydie Michaillat Mayer, Henning Jessen, Andreas Mayer
Published in: eLIFE (in press), 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.1101/2023.02.14.528555