Objective Percutaneous insertions of instruments are commonly used during minimally invasive surgery (MIS) for delivering diagnostic agents and performing therapeutic interventions. These instruments often deviate from their intended paths due to tissue deformation and physiological processes. Inaccurate instrument placement may lead to misdiagnosis, ineffective therapy, or traumatic effects due to medical complications. The ability to accurately visualize the instrument in real-time, without providing toxic radiation, as it is steered within the human body would permit a gamut of novel diagnostic and therapeutic options, including on-site pathology and targeted drug delivery. Such an advance would truly revolutionize MIS. The goal of INSPIRE is to develop and evaluate an innovative instrument that integrates shape sensing technology for ablation procedures.MIS using radiofrequency ablation (RFA) is a state-of-the-art procedure for tumor destruction. The significant challenge within this procedure is to develop a better visualization technique to position the RFA instrument precisely near the tumor. Computed tomography is the current image-guided technique, but damage is easily inflicted during the procedure by misplacement of the RFA instrument and extensive radiation exposure. INSPIRE aims to integrate optical shape sensing (OSS) hardware and software within the RFA instrument to guide positioning for safe, accurate, and effective minimally invasive destruction of bone tumors, without radiation exposure. INSPIRE involves clinical and industrial collaborations (e.g. FBGS, Medtronic, Philips) and a business development team. The results gained will be applicable to a range of rigid and flexible instruments, and to an assortment of personalized treatment scenarios. INSPIRE is strongly motivated by the existing need to further reduce the invasiveness of MIS, improve clinical outcomes, minimize patient trauma, and enable treatment of inoperable patients. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringinformation engineeringtelecommunicationsradio technologyradio frequencynatural sciencescomputer and information sciencessoftwaremedical and health sciencesclinical medicinesurgerymedical and health sciencesbasic medicinepathology Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-2017-PoC - ERC-Proof of Concept Call for proposal ERC-2017-PoC See other projects for this call Funding Scheme ERC-POC - Proof of Concept Grant Host institution UNIVERSITEIT TWENTE Net EU contribution € 150 000,00 Address DRIENERLOLAAN 5 7522 NB Enschede Netherlands See on map Region Oost-Nederland Overijssel Twente Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 150 000,00 Beneficiaries (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITEIT TWENTE Netherlands Net EU contribution € 150 000,00 Address DRIENERLOLAAN 5 7522 NB Enschede See on map Region Oost-Nederland Overijssel Twente Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 150 000,00
