Unravelling the mechanisms that allow endosymbionts to make themselves at home within hosts, from transfer to transit.

Información del proyecto

Host Sweet Home

Identificador del acuerdo de subvención: 790531

DOI

10.3030/790531

Proyecto finalizado el 5 Octubre 2019

Fecha de la firma de la CE 13 Marzo 2018

Fecha de inicio 1 Octubre 2018

Fecha de finalización 31 Octubre 2021

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 185 857,20

Aportación de la UE

€ 185 857,20

Coordinado por

LUNDS UNIVERSITET
Sweden

Objetivo

Endosymbiotic bacteria are usually not infectious, they have been thought to exclusively transfer vertically from the host mother to her offspring. Consequently we do often observe congruence between the phylogenetic trees of endosymbiotic bacteria and their host species, but not always. Evidences for the horizontal transfer of endosymbiotic bacteria between highly divergent host species have recently been accumulating, especially from studies in Insects. My own research on this topic led me to hypothesise that endosymbiotic strains not transferring horizontally may have lost the ability to do so and to establish into naïve hosts, contrasting to strains found in divergent host species. Instead of transferring, these strains would transit from a generalist state, able to jump and establish into naïve hosts, towards a more specialist state found in only few host species.
Using Wolbachia bacteria-butterfly host associations and a multidisciplinary approach, I aim at (I) testing the evolutionary relevance of horizontal transfer of symbionts, (II) phenotypically characterizing generalist and specialist symbionts, and (III) identifying the molecular bases to the establisment of symbiosis.
The novelty of this project lies into solving the dilemma associated to the endosymbiotic lifestyle: to maintain the mechanisms allowing transfer between hosts or to transit towards a specialised relationship with the host. ‘Host Sweet Home’ will to unravel the evolutionary history, and the constraints and outcomes of endosymbiosis. I will produce a large amount of genetic data, which analysis will result in highly significant research in the field of symbiosis, with a potential impact beyond the field of Evolutionary Ecology.

Ámbito científico (EuroSciVoc)

• ciencias naturales › ciencias biológicas › genética › ADN
• ciencias naturales › ciencias biológicas › ecología › ecología evolutiva
• ciencias naturales › ciencias biológicas › ciencias biológicas del comportamiento › etología › interacción biológica
• ciencias naturales › ciencias biológicas › zoología › entomología
• ciencias naturales › ciencias biológicas › genética › genoma

Programa(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions PROGRAMA PRINCIPAL
  
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
  

Tema(s)

• MSCA-IF-2017 - Individual Fellowships
  

Régimen de financiación

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Convocatoria de propuestas

H2020-MSCA-IF-2017

Coordinador

LUNDS UNIVERSITET

• Aportación neta de la UEn: € 185 857,20
• Dirección: Paradisgatan 5c ; 22100 Lund ; Suecia
• Región: Södra Sverige › Sydsverige › Skåne län
• Tipo de actividad: Higher or Secondary Education Establishments
• Coste total: € 185 857,20