DYNAMICE: An integrated framework for biomechanical phenotyping of arteries to disentangle mechanical causes of arterial stiffening in diabetes

Project Information

DYNAMICE

Grant agreement ID: 793805

DOI

10.3030/793805

Project closed

EC signature date 19 March 2018

Start date 1 April 2019

End date 31 March 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 260 929,80

EU contribution

€ 260 929,80

Coordinated by

UNIVERSITEIT MAASTRICHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (24)

Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging

Author(s): Bart Spronck, Jacopo Ferruzzi, Chiara Bellini, Alexander W. Caulk, Sae-Il Murtada, Jay D. Humphrey
Published in: Journal of Hypertension, Issue 38/7, 2020, Page(s) 1312-1321, ISSN 0263-6352
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000002400

The Putative Role of Methylglyoxal in Arterial Stiffening: A Review

Author(s): Myrthe M van der Bruggen, Bart Spronck, Tammo Delhaas, Koen D. Reesink, Casper G. Schalkwijk
Published in: Heart, Lung and Circulation, 2021, ISSN 1443-9506
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.hlc.2021.06.527

Improved Quantification of Cell Density in the Arterial Wall-A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy

Author(s): Koen W F van der Laan, Koen D Reesink, Myrthe M van der Bruggen, Armand M G Jaminon, Leon J Schurgers, Remco T A Megens, Wouter Huberts, Tammo Delhaas, Bart Spronck
Published in: Frontiers in Physiology, 2022, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.814434

Reply to Comments: Using the Cardio-Ankle Vascular Index (CAVI) or the Mathematical Correction Form (CAVI0) in Clinical Practice

Author(s): Bart Spronck, Alexander Jurko, Michal Mestanik, Alberto P. Avolio, Ingrid Tonhajzerova
Published in: International Journal of Molecular Sciences, Issue 21/7, 2020, Page(s) 2647, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072647

Covid-19 Effects on ARTErial StIffness and Vascular AgeiNg: CARTESIAN Study Rationale and Protocol

Author(s): Rosa Maria Bruno, Bart Spronck, Bernhard Hametner, Alun Hughes, Patrick Lacolley, Christopher C. Mayer, Maria Lorenza Muiesan, Chakravarthi Rajkumar, Dimitrios Terentes-Printzios, Thomas Weber, Tine Willum Hansen, Pierre Boutouyrie, on behalf of the ARTERY Society
Published in: Artery Research, 2020, ISSN 1876-4401
Publisher: Atlantis Press International B.V.
DOI: 10.2991/artres.k.201124.001

Novel Biomarkers of Early Atherosclerotic Changes for Personalised Prevention of Cardiovascular Disease in Cervical Cancer and Human Papillomavirus Infection

Author(s): Ingrid Tonhajzerova, Lucia Olexova, Alexander Jurko, Bart Spronck, Tomas Jurko, Nikola Sekaninova, Zuzana Visnovcova, Andrea Mestanikova, Erik Kudela, Michal Mestanik
Published in: International Journal of Molecular Sciences, Issue 20/15, 2019, Page(s) 3720, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20153720

Adults With Type 2 Diabetes Mellitus Exhibit a Greater Exercise-Induced Increase in Arterial Stiffness and Vessel Hemodynamics

Author(s): Alexandra B. Cooke, Kaberi Dasgupta, Bart Spronck, James E. Sharman, Stella S. Daskalopoulou
Published in: Hypertension, Issue 75/6, 2020, Page(s) 1565-1573, ISSN 0194-911X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.120.14778

Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome

Author(s): Cristina I. Caescu, Jens Hansen, Brittany Crockett, Wenzhen Xiao, Pauline Arnaud, Bart Spronck, Alan Weinberg, Takeshi Hashimoto, Sae-Il Murtada, Roshan Borkar, James M. Gallo, Guillaume Jondeau, Catherine Boileau, Jay D. Humphrey, John Cijiang He, Ravi Iyengar, Francesco Ramirez
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, 2021, ISSN 1079-5642
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.121.316464

An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions

Author(s): Myrthe M. van der Bruggen, Koen D. Reesink, Paul J. M. Spronck, Nicole Bitsch, Jeroen Hameleers, Remco T. A. Megens, Casper G. Schalkwijk, Tammo Delhaas, Bart Spronck
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-81151-5

From Uniaxial Testing of Isolated Layers to a Tri-Layered Arterial Wall: A Novel Constitutive Modelling Framework

Author(s): Alessandro Giudici, Ashraf W. Khir, Jason M. Szafron, Bart Spronck
Published in: Annals of Biomedical Engineering, 2021, ISSN 0090-6964
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10439-021-02775-2

Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular Structure and Function and the ARTERY Society

Author(s): Luca Zanoli, Marie Briet, Jean P. Empana, Pedro G. Cunha, Kaisa M. Mäki-Petäjä, Athanase D. Protogerou, Alain Tedgui, Rhian M. Touyz, Ernesto L. Schiffrin, Bart Spronck, Philippe Bouchard, Charalambos Vlachopoulos, Rosa M. Bruno, Pierre Boutouyrie
Published in: Journal of Hypertension, Issue 38/9, 2020, Page(s) 1682-1698, ISSN 0263-6352
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000002508

Pressure-Corrected Carotid Stiffness and Young’s Modulus: Evaluation in an Outpatient Clinic Setting

Author(s): Myrthe van der Bruggen, Bart Spronck, Siske Bos, Maarten H G Heusinkveld, Stefano Taddei, Lorenzo Ghiadoni, Tammo Delhaas, Rosa Maria Bruno, Koen D Reesink
Published in: American Journal of Hypertension, 2021, ISSN 0895-7061
Publisher: Oxford University Press
DOI: 10.1093/ajh/hpab028

Five years of cardio-ankle vascular index (CAVI) and CAVI0: how close are we to a pressure-independent index of arterial stiffness?

Author(s): Alessandro Giudici, Ashraf W. Khir, Koen D. Reesink, Tammo Delhaas, Bart Spronck
Published in: Journal of Hypertension, 2021, ISSN 0263-6352
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000002928

Easy conversion of cardio-ankle vascular index into CAVI0

Author(s): Bart Spronck, Michal Mestanik, Ingrid Tonhajzerova, Alexander Jurko, Isabella Tan, Mark Butlin, Alberto P. Avolio
Published in: Journal of Hypertension, Issue 37/9, 2019, Page(s) 1913-1914, ISSN 0263-6352
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000002166

Disentangling Arterial Stiffness and Blood Pressure

Author(s): Bart Spronck
Published in: Heart, Lung and Circulation, 2021, ISSN 1443-9506
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.hlc.2021.05.086

Age-Specific Acute Changes in Carotid–Femoral Pulse Wave Velocity With Head-up Tilt

Author(s): Giacomo Pucci, Bart Spronck, Alberto P Avolio, Lisanne Tap, Gaetano Vaudo, Fabio Anastasio, Anton Van Den Meiracker, Francesco Mattace-Raso
Published in: American Journal of Hypertension, Issue 33/12, 2020, Page(s) 1112-1118, ISSN 0895-7061
Publisher: Oxford University Press
DOI: 10.1093/ajh/hpaa101

Intra-Operative Video-Based Measurement of Biaxial Strains of the Ascending Thoracic Aorta

Author(s): Shaiv Parikh, Berta Ganizada, Gijs Debeij, Ehsan Natour, Jos Maessen, Bart Spronck, Leon Schurgers, Tammo Delhaas, Wouter Huberts, Elham Bidar, Koen Reesink
Published in: Biomedicines, 2021, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9060670

Physiological basis for longitudinal motion of the arterial wall

Author(s): Chloe E. Athaide, Bart Spronck, Jason S. Au
Published in: American Journal of Physiology - Heart and Circulatory Physiology, 2022, Page(s) H689-H701, ISSN 0363-6135
Publisher: American Physiological Society
DOI: 10.1152/ajpheart.00567.2021

Excessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice

Author(s): Bart Spronck, Marcos Latorre, Mo Wang, Sameet Mehta, Alexander W. Caulk, Pengwei Ren, Abhay B. Ramachandra, Sae-Il Murtada, Alexia Rojas, Chang-Shun He, Bo Jiang, Matthew R. Bersi, George Tellides, Jay D. Humphrey
Published in: Journal of the Royal Society. Interface, 2021, ISSN 1742-5689
Publisher: The Royal Society
DOI: 10.1098/rsif.2021.0336

Single M-Line Is as Reliable as Multiple M-Line Ultrasound for Carotid Artery Screening

Author(s): Afrah E. F. Malik; Afrah E. F. Malik; Tammo Delhaas; Tammo Delhaas; Bart Spronck; Bart Spronck; Ronald M. A. Henry; Ronald M. A. Henry; Jayaraj Joseph; Coen D. A. Stehouwer; Coen D. A. Stehouwer; Werner H. Mess; Koen D. Reesink; Koen D. Reesink
Published in: Frontiers in Physiology, Issue 8, 2021, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.787083

Predictive Ability of Pressure-Corrected Arterial Stiffness Indices: Comparison of Pulse Wave Velocity, Cardio-Ankle Vascular Index (CAVI), and CAVI0

Author(s): Bart Spronck, Mary Jo Obeid, Mahati Paravathaneni, Naga Vaishnavi Gadela, Gurpreet Singh, Caroline A. Magro, Varsha Kulkarni, Soumya Kondaveety, Keerthi Chandrika Gade, Rushik Bhuva, Colin M. Kulick-Soper, Nicolas Sanchez, Scott Akers, Julio A. Chirinos
Published in: American Journal of Hypertension, 2022, ISSN 0895-7061
Publisher: Oxford University Press
DOI: 10.1093/ajh/hpab168

A first step towards recognizing the fundamental role of smooth muscle tone in large artery (dys)function?

Author(s): Alessandro Giudici, Bart Spronck
Published in: Journal of Hypertension, 2022, ISSN 0263-6352
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003063

The Role of Layer-Specific Residual Stresses in Arterial Mechanics: Analysis via a Novel Modelling Framework

Author(s): Alessandro Giudici, Bart Spronck
Published in: Artery Research, 2022, ISSN 1876-4401
Publisher: BioMed Central Ltd.
DOI: 10.1007/s44200-022-00013-1

Measuring Arterial Stiffness in Animal Experimental Studies

Author(s): Mark Butlin, Isabella Tan, Bart Spronck, Alberto P. Avolio
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, Issue 40/5, 2020, Page(s) 1068-1077, ISSN 1079-5642
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.119.313861