Objective
Plant diseases are an economic, environmental and social threat affecting crop production worldwide. Effective plant disease resistance is a critical requirement to maintain world food security. Deployment of resistance (R) genes in crops is currently the most effective strategy for genetic control of disease. However, this type of resistance can be short-lived and is often affected by environmental stresses such as elevated temperature, which is highly concerning in the context of global warming.
The proposed research aims to decipher the signaling function of intracellular plant immune receptors of the NOD-like receptor (NLR) family encoded by canonical and non-canonical (truncated) R genes.
The opportunity at the heart of this project arises from the finding that N-terminal domains of NLRs act as potent signaling domains that are self-sufficient to activate immune responses independently of pathogen recognition and preliminary data indicate that this signaling activity is not compromised at elevated temperature (unlike full length NLRs). Hence, manipulating signaling downstream of pathogen recognition may lower the risk of resistance breakdown and provide a source of disease resistance adapted to global warming. Naturally occurring truncated NLRs lacking some of the canonical domains but containing N-terminal signaling domains are promising candidates to investigate this hypothesis. “SPLINTER” will focus on the signaling function of canonical and non-canonical NLRs in the major vegetable crop tomato, and the model plant Arabidopsis, mainly in response to the devastating phytopathogenic bacteria Ralstonia solanacearum and under temperature stress. This project will also establish a long-term research path for an early-mid career researcher returning to her home country.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- medical and health sciences basic medicine immunology
- medical and health sciences health sciences nutrition
- agricultural sciences agriculture, forestry, and fisheries agriculture
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75007 Paris
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.