Endothelial Hedgehog autocrine signaling at the Blood Brain Barrier controls inflammatory Central Nervous System lesion size and severity through Gas1 co-receptor modulation.

Project Information

EFHHBBBMS

Grant agreement ID: 794726

DOI

10.3030/794726

Project closed

EC signature date 23 February 2018

Start date 15 January 2019

End date 14 January 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 173 076,00

EU contribution

€ 173 076,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Full-length dhh and N-terminal shh act as competitive antagonists to regulate angiogenesis and vascular permeability

Author(s): Pierre-Louis Hollier, Candice Chapouly, Aissata Diop, Sarah Guimbal, Lauriane Cornuault, Alain-Pierre Gadeau, Marie-Ange Renault
Published in: Cardiovascular Research, 2020, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvaa285

Blood–brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans

Author(s): Pierre Mora, Pierre-Louis Hollier, Sarah Guimbal, Alice Abelanet, Aïssata Diop, Lauriane Cornuault, Thierry Couffinhal, Sam Horng, Alain-Pierre Gadeau, Marie-Ange Renault, Candice Chapouly
Published in: PLOS Biology, Issue 18/11, 2020, Page(s) e3000946, ISSN 1544-9173
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3000946

Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes)

Author(s): Candice Chapouly, Pierre-Louis Hollier, Sarah Guimbal, Lauriane Cornuault, Alain-Pierre Gadeau, Marie-Ange Renault
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, ISSN 1079-5642
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.120.314441