NMR insights on the soluble Guanylyl Cyclase conformational dynamics to illuminate the SIGNaling pathway

Project Information

NMRSIGN

Grant agreement ID: 795175

DOI

10.3030/795175

Project closed

EC signature date 19 March 2018

Start date 1 August 2018

End date 31 July 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 164 653,20

EU contribution

€ 164 653,20

Coordinated by

PANEPISTIMIO PATRON
Greece

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Publications

Peer reviewed articles (2)

Backbone and side chain NMR assignments of the H-NOX domain from Nostoc sp. in complex with BAY58-2667 (cinaciguat)

Author(s): Garyfallia I. Makrynitsa, Aikaterini I. Argyriou, Georgios Dalkas, Dimitra A. Georgopoulou, Marina Bantzi, Athanassios Giannis, Andreas Papapetropoulos & Georgios A. Spyroulias
Published in: Biomolecular NMR Assignments, 2020, ISSN 1874-270X
Publisher: Springer Nature
DOI: 10.1007/s12104-020-09982-3

Replacement of heme by soluble guanylate cyclase (sGC) activators abolishes heme-nitric oxide/oxygen (H-NOX) domain structural plasticity

Author(s): Aikaterini I. Argyriou, Garyfallia I. Makrynitsa, Georgios Dalkas, Dimitra A. Georgopoulou, Konstantinos Salagiannis, Vassiliki Vazoura, Andreas Papapetropoulos, Stavros Topouzis, Georgios A. Spyroulias
Published in: Current Research in Structural Biology, Issue Volume 3, 2021, Page(s) 324-336, ISSN 2665-928X
Publisher: Elsevier
DOI: 10.1016/j.crstbi.2021.11.003