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Interaction of squalene-based anti-cancer and neuroprotective drugs with cell membranes: in silico study

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Curvature increases permeability of the plasma membrane for ions, water and the anti-cancer drugs cisplatin and gemcitabine

Author(s): Semen Yesylevskyy, Timothée Rivel, Christophe Ramseyer
Published in: Scientific Reports, 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-53952-2

Phospholipid distribution in the cytoplasmic membrane of Gram-negative bacteria is highly asymmetric, dynamic, and cell shape-dependent

Author(s): Mikhail Bogdanov, Kyrylo Pyrshev, Semen Yesylevskyy, Sergey Ryabichko, Vitalii Boiko, Pavlo Ivanchenko, Ramziya Kiyamova, Ziqiang Guan, Christophe Ramseyer, William Dowhan
Published in: Science Advances, 6/23, 2020, Page(s) eaaz6333, ISSN 2375-2548
Publisher: Science Advances
DOI: 10.1126/sciadv.aaz6333

Lipoproteins LDL versus HDL as nanocarriers to target either cancer cells or macrophages

Author(s): Tarik Hadi, Christophe Ramseyer, Thomas Gautier, Pierre-Simon Bellaye, Tatiana Lopez, Antonin Schmitt, Sarah Foley, Semen Yesylevskyy, Thibault Minervini, Romain Douhard, Lucile Dondaine, Lil Proukhnitzky, Samir Messaoudi, Maeva Wendremaire, Mathieu Moreau, Fabrice Neiers, Bertrand Collin, Franck Denat, Laurent Lagrost, Carmen Garrido, Frederic Lirussi
Published in: JCI Insight, 5/24, 2020, ISSN 2379-3708
Publisher: JCI
DOI: 10.1172/jci.insight.140280

The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin

Author(s): Timothée Rivel, Christophe Ramseyer, Semen Yesylevskyy
Published in: Scientific Reports, 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-41903-w

Stacking as a Key Property for Creating Nanoparticles with Tunable Shape: The Case of Squalenoyl-Doxorubicin

Author(s): Julie Mougin, Semen O. Yesylevskyy, Claudie Bourgaux, David Chapron, Jean-Philippe Michel, Franco Dosio, Barbara Stella, Christophe Ramseyer, Patrick Couvreur
Published in: ACS Nano, 13/11, 2019, Page(s) 12870-12879, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.9b05303

TTAPE-Me dye is not selective to cardiolipin and binds to common anionic phospholipids nonspecifically

Author(s): Kyrylo Pyrshev, Semen Yesylevskyy, Mikhail Bogdanov
Published in: Biophysical Journal, 2021, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2021.06.039

The fate of therapeutic nanoparticles in a model biological medium: interactions with serum albumin

Author(s): F. Gobeaux, J. Bizeau, F. Samson, L. Marichal, I. Grillo, F. Wien, S. O. Yesylevsky, C. Ramseyer, M. Rouquette, S. Lepêtre-Mouelhi, D. Desmaële, P. Couvreur, P. Guenoun, J-P.Renault, F. Testard
Published in: SFNano - C’nano, Dec 2019, Dijon, France., 2019
Publisher: SFNano - C’nano, Dec 2019, Dijon, France.