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Advanced pulmonary vascular monitoring for optimum Nitric Oxide delivery in acute respiratory distress syndrome. Expanding Nitric Oxide applications

Objective

Acute respiratory distress syndrome (ARDS) is the most severe form of respiratory failure. Pulmonary vascular dysfunction during ARDS increases mortality and therapies focused in improving pulmonary vascular mechanics could improve patient prognosis. Inhaled Nitric Oxide (NO), improves pulmonary vascular mechanics, but despite of this effect, has not proven to improve outcomes in ARDS. One of the most representative problems is the lack of information of the quantitative dose used and all consequences that this uncontrolled administration entails. In this project we aim to establish bedside physiologic variables and algorithms to guide efficient NO delivery during ARDS. It will involve the collaboration between an enterprise that has developed a new NO delivering system and is looking for expanding its applications and a researcher with expertise in physiology, imaging and biologic variables monitoring. As a result of this collaboration, the company will gain a quantitative way of determining the treatment efficiency that could be used in this and other applications, a more patient-oriented and physiology-focused approach for this product and the researcher will acquire skills for turning his career from the academy to the industry side. This research will combine edge technology to define bedside tools for patients monitoring with the application of this information for improving the performance of the delivery system. Clinically relevant imaging tools such as Magnetic Resonance Imaging and Positron Emission Tomography, and pulmonary artery pressure waveform advanced analysis as well as other non or minimum invasive tools will be studied in animal models. Software, algorithm or dedicated products will be proposed for incorporation into the gas delivery system or clinical monitors for improving patient safety. We are expecting a clear benefit to emerging European-based technologies that make our companies more competitive and well-positioned in a worldwide business.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-SE - Society and Enterprise panel

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2017

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Coordinator

INGENIERIA Y TECNICAS CLINICAS SA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 158 121,60
Address
CALLE TUNGSTENO 11-13
28500 ARGANDA DEL REY - MADRID
Spain

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 158 121,60
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