Objective
"The study of emergent pollutants is included in the priority research guidelines of many environmental- and health-regulation
bodies, such as the World Health Organisation, the USA Environmental Protection Agency or the EFSA and ECHA agencies
of the European Commission. In this regard this regulatory bodies have identified substances of very high concern, including
Endocrine Disruptors (EDCs). An emerging concern is related to substances that are able to modify cellular regulatory
mechanisms long after the actual exposure occurred, a long-term effect mediated by chemical chromatin changes and
integrated into the concept of epigenetics. The prevalent hypothesis is to use the ""epigenetic foot-print” as a tool to evaluate
the exposure of a given organism to toxicants, with the ultimate goal of identify determine if epigenetic signatures
characterized after early development exposures are maintained through time once the pollutant exposure ceased, and if
those can cause adverse effects on the exposed animals. In that context the main goal of the present proposal is to identify
epigenetic footprints characteristic of early development exposures to EDCs in zebrafish. This project intends to: 1) To identify common epigenetic markers regulated by EDC exposures during early development; 2) To integrate transcriptomic and epigenetic platforms to identify relevant biological pathways characteristic of EDCs exposures. Results from this study would be very useful to identify target epigenetic biomarkers and develop cost-effective high-throughput methodologies to screen for epigenetic signatures after EDCs exposures."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-RI - RI – Reintegration panel
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.