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Novel precision technological platforms to promote non-invasive early diagnosis, eradication and prevention of cancer relapse: proof of concept in the bladder carcinoma.

Deliverables

At least 5 conferences and at least 3 peer-reviewed papers

At least 5 conferences and at least 3 peer-reviewed papers

Second plan for dissemination and exploitation for ( PUDF)

Second plan for dissemination and exploitation for ( PUDF)

Project website and logo

Project website and logo

First plan for dissemination and exploitation (using and disseminating the foreground (=PUDF))

First plan for dissemination and exploitation (using and disseminating the foreground (=PUDF))

Publications

Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody

Author(s): Lena Cohen, Irit Sagi, Einat Bigelman, Inna Solomonov, Anna Aloshin, Jeremy Ben-Shoshan, Zach Rozenbaum, Gad Keren, Michal Entin-Meer
Published in: PLOS ONE, Issue 15/4, 2020, Page(s) e0231202, ISSN 1932-6203
DOI: 10.1371/journal.pone.0231202

An Application of Multivariate Data Analysis to Photoacoustic Imaging for the Spectral Unmixing of Gold Nanorods in Biological Tissues

Author(s): Mirko Maturi, Paolo Armanetti, Luca Menichetti, Mauro Comes Franchini
Published in: Nanomaterials, Issue 11/1, 2021, Page(s) 142, ISSN 2079-4991
DOI: 10.3390/nano11010142

Adhesion force spectroscopy with nanostructured colloidal probes reveals nanotopography-dependent early mechanotransductive interactions at the cell membrane level

Author(s): M. Chighizola, A. Previdi, T. Dini, C. Piazzoni, C. Lenardi, P. Milani, C. Schulte, A. Podestà
Published in: Nanoscale, Issue 12/27, 2020, Page(s) 14708-14723, ISSN 2040-3364
DOI: 10.1039/d0nr01991g

Distinct extracellular–matrix remodeling events precede symptoms of inflammation

Author(s): Elee Shimshoni, Idan Adir, Ran Afik, Inna Solomonov, Anjana Shenoy, Miri Adler, Luca Puricelli, Fabio Sabino, Simonas Savickas, Odelia Mouhadeb, Nathan Gluck, Sigal Fishman, Lael Werner, Tomer-Meir Salame, Dror S. Shouval, Chen Varol, Ulrich auf dem Keller, Alessandro Podestà, Tamar Geiger, Paolo Milani, Uri Alon, Irit Sagi
Published in: Matrix Biology, Issue 96, 2021, Page(s) 47-68, ISSN 0945-053X
DOI: 10.1016/j.matbio.2020.11.001

Stiffening of DU145 prostate cancer cells driven by actin filaments – microtubule crosstalk conferring resistance to microtubule-targeting drugs

Author(s): Andrzej Kubiak, Matteo Chighizola, Carsten Schulte, Natalia Bryniarska, Julita Wesołowska, Maciej Pudełek, Małgorzata Lasota, Damian Ryszawy, Agnieszka Basta-Kaim, Piotr Laidler, Alessandro Podestà, Małgorzata Lekka
Published in: Nanoscale, Issue 13/12, 2021, Page(s) 6212-6226, ISSN 2040-3364
DOI: 10.1039/d0nr06464e

Mechanotransduction in neuronal cell development and functioning

Author(s): Matteo Chighizola, Tania Dini, Cristina Lenardi, Paolo Milani, Alessandro Podestà, Carsten Schulte
Published in: Biophysical Reviews, Issue 11/5, 2019, Page(s) 701-720, ISSN 1867-2450
DOI: 10.1007/s12551-019-00587-2

Current concepts in nanostructured contrast media development for in vivo photoacoustic imaging

Author(s): Mirko Maturi, Erica Locatelli, Ilaria Monaco, Mauro Comes Franchini
Published in: Biomaterials Science, Issue 7/5, 2019, Page(s) 1746-1775, ISSN 2047-4830
DOI: 10.1039/c8bm01444b

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

Author(s): Francesca Nardelli, Michela Ghitti, Giacomo Quilici, Alessandro Gori, Qingqiong Luo, Andrea Berardi, Angelina Sacchi, Matteo Monieri, Greta Bergamaschi, Wolfgang Bermel, Fuxiang Chen, Angelo Corti, Flavio Curnis, Giovanna Musco
Published in: Chemical Communications, 2019, ISSN 1359-7345
DOI: 10.1039/c9cc08518a

MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy

Author(s): Mark Owyong, Jonathan Chou, Renske JE van den Bijgaart, Niwen Kong, Gizem Efe, Carrie Maynard, Dalit Talmi-Frank, Inna Solomonov, Charlotte Koopman, Elin Hadler-Olsen, Mark Headley, Charlene Lin, Chih-Yang Wang, Irit Sagi, Zena Werb, Vicki Plaks
Published in: Life Science Alliance, Issue 2/6, 2019, Page(s) e201800226, ISSN 2575-1077
DOI: 10.26508/lsa.201800226

LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis

Author(s): Mordehay Klepfish, Tamar Gross, Milena Vugman, Nikolaos A. Afratis, Sapir Havusha-Laufer, Eli Brazowski, Inna Solomonov, Chen Varol, Irit Sagi
Published in: Frontiers in Immunology, Issue 11, 2020, ISSN 1664-3224
DOI: 10.3389/fimmu.2020.00480

Influence of natural convection on gold nanorods-assisted photothermal treatment of bladder cancer in mice

Author(s): Ean H. Ooi, Viktor Popov, Massimo Alfano, Jason K. K. Cheong
Published in: International Journal of Hyperthermia, Issue 37/1, 2020, Page(s) 634-650, ISSN 0265-6736
DOI: 10.1080/02656736.2020.1771437

Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts

Author(s): Kwanghee Kim, Wenhuo Hu, François Audenet, Nima Almassi, Aphrothiti J. Hanrahan, Katie Murray, Aditya Bagrodia, Nathan Wong, Timothy N. Clinton, Shawn Dason, Vishnu Mohan, Sylvia Jebiwott, Karan Nagar, Jianjiong Gao, Alex Penson, Chris Hughes, Benjamin Gordon, Ziyu Chen, Yiyu Dong, Philip A. Watson, Ricardo Alvim, Arijh Elzein, Sizhi P. Gao, Emiliano Cocco, Alessandro D. Santin, Irina Ostrovnaya,
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-15885-7

Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression

Author(s): Alakesh Das, Vishnu Mohan, Venkat Raghavan Krishnaswamy, Inna Solomonov, Irit Sagi
Published in: Cancer and Metastasis Reviews, 2019
DOI: 10.1007/s10555-019-09813-5