Real-time diffusion NMR analysis of mixtures

Project Information

DINAMIX

Grant agreement ID: 801774

DOI

10.3030/801774

Project closed

EC signature date 28 August 2018

Start date 1 February 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 307,00

EU contribution

€ 1 499 307,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (28)

Speedy Component Resolution Using Spatially Encoded Diffusion NMR Data

Author(s): Benjamin Lorandel, Hugo Rocha, Oksana Cazimajou, Rituraj Mishra, Aurélie Bernard, Paul Bowyer, Mathias Nilsson, Jean‐Nicolas Dumez
Published in: Magnetic Resonance in Chemistry, Issue 63, 2024, Page(s) 49-61, ISSN 0749-1581
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/mrc.5488

Online Reaction Monitoring with Fast and Flow-Compatible Diffusion NMR Spectroscopy

Author(s): Achille Marchand, Rituraj Mishra, Aurélie Bernard, Jean-Nicolas Dumez
Published in: Chemistry: A European Journal, 2022, ISSN 1521-3765
Publisher: Wiley-VCH GmbH
DOI: 10.1002/chem.202201175

Optimisation of spatially encoded diffusion ordered NMR spectroscopy for the analysis of mixtures

Author(s): Corentin Jacquemmoz, Rituraj Mishra, Ludmilla Guduff, Carine Heijenoort, Jean‐Nicolas Dumez
Published in: Magnetic Resonance in Chemistry, 2021, ISSN 0749-1581
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/mrc.5194

Optimization of heteronuclear ultrafast 2D NMR for the study of complex mixtures hyperpolarized by dynamic nuclear polarization

Author(s): Clément Praud, Victor Ribay, Arnab Dey, Benoît Charrier, Joris Mandral, Jonathan Farjon, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Analytical Methods, Issue 15, 2024, Page(s) 6209-6219, ISSN 1759-9660
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3ay01681a

Hyperpolarized ¹H and ¹³C NMR Spectroscopy in a Single Experiment for Metabolomics

Author(s): Arnab Dey, Benoît Charrier, Victor Ribay, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Analytical Chemistry, Issue 95, 2023, Page(s) 16861-16867, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.3c02614

Solution‐State 2D NMR Spectroscopy of Mixtures HyperpolarizedUsing Optically Polarized Crystals

Author(s): Anna J. Parker, Arnab Dey, Mohammad Usman Qureshi, Jakob M. Steiner, John W. Blanchard, Jochen Scheuer, Nikolas Tomek, Stephan Knecht, Felix Josten, Christoph Müller, Patrick Hautle, Ilai Schwartz, Patrick Giraudeau, Tim R. Eichhorn, Jean‐Nicolas Dumez
Published in: Angewandte Chemie International Edition, Issue 62, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202312302

Spatially encoded pure-shift diffusion-ordered NMR spectroscopy yielded by chirp excitation

Author(s): Rituraj Mishra, Jonathan R.J. Yong, Corentin Jacquemmoz, Benjamin Lorandel, Mohammadali Foroozandeh, Jean-Nicolas Dumez
Published in: Journal of Magnetic Resonance, Issue 359, 2024, Page(s) 107628, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2024.107628

Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts

Author(s): Sami Jannin, Jean-Nicolas Dumez, Patrick Giraudeau, Dennis Kurzbach
Published in: Journal of Magnetic Resonance, Issue 305, 2019, Page(s) 41-50, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2019.06.001

In-line Multidimensional NMR Monitoring of Photochemical Flow Reactions

Author(s): Margherita Bazzoni, Célia Lhoste, Justine Bonnet, Kouakou Eric Konan, Aurélie Bernard, Patrick Giraudeau, François-Xavier Felpin, Jean-Nicolas Dumez
Published in: Chemistry: A European Journal, 2023, ISSN 1521-3765
Publisher: Wiley VCH GmbH
DOI: 10.1002/chem.202203240

Theoretical analysis of flow effects in spatially-encoded diffusion

Author(s): Rituraj MIshra, Jean-Nicolas Dumez
Published in: Journal of Chemical Physics, 2023, ISSN 0021-9606
Publisher: American Institute of Physics
DOI: 10.1063/5.0130125

Pure Shift NMR in Continuous Flow

Author(s): Margherita Bazzoni, Armand Régheasse, Elsa Caytan, François‐Xavier Felpin, Patrick Giraudeau, Aurélie Bernard, Ralph W. Adams, Gareth A. Morris, Mathias Nilsson, Jean‐Nicolas Dumez
Published in: Chemistry – A European Journal, Issue 31, 2025, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202403385

Single‐Scan Ultraselective NMR Experiments with Preserved Sensitivity

Author(s): Margherita Bazzoni, Rituraj Mishra, Jean‐Nicolas Dumez
Published in: Angewandte Chemie International Edition, Issue 62, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202314598

Ultrafast 2D 1 H– 1 H NMR spectroscopy of DNP-hyperpolarised substrates for the analysis of mixtures

Author(s): Kawarpal Singh, Corentin Jacquemmoz, Patrick Giraudeau, Lucio Frydman, Jean-Nicolas Dumez
Published in: Chemical Communications, Issue 57/65, 2021, Page(s) 8035-8038, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc03079e

Accounting for gradient non-uniformity in spatially-encoded diffusion-ordered NMR spectroscopy

Author(s): Benjamin Lorandel, Rituraj Mishra, Oksana Cazimajou, Achille Marchand, Aurélie Bernard, Jean-Nicolas Dumez
Published in: Journal of Magnetic Resonance, Issue 355, 2023, Page(s) 107543, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2023.107543

Broadband ultrafast 2D NMR spectroscopy for online monitoring in continuous flow

Author(s): Célia Lhoste, Margherita Bazzoni, Justine Bonnet, Aurélie Bernard, François-Xavier Felpin, Patrick Giraudeau, Jean-Nicolas Dumez
Published in: The Analyst, Issue 148, 2024, Page(s) 5255-5261, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3an01165h

Hyperpolarized NMR metabolomics

Author(s): Victor Ribay, Clément Praud, Marine P.M. Letertre, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Current Opinion in Chemical Biology, 2023, ISSN 1367-5931
Publisher: Elsevier BV
DOI: 10.1016/j.cbpa.2023.102307

NMR methods for the analysis of mixtures

Author(s): Jean-Nicolas Dumez
Published in: Chemical Communications, 2022, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cc05053f

Interleaved spatial/spectral encoding in ultrafast 2D NMR spectroscopy

Author(s): Bertrand Plainchont, Patrick Giraudeau, Jean-Nicolas Dumez
Published in: Journal of Magnetic Resonance, Issue 305, 2019, Page(s) 112-121, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2019.06.010

Autonomous reaction self-optimization using in-line high-field NMR spectroscopy

Author(s): Nour El Sabbagh, Margherita Bazzoni, Yuliia Horbenko, Aurélie Bernard, Daniel Cortés-Borda, Patrick Giraudeau, François-Xavier Felpin, Jean-Nicolas Dumez
Published in: Reaction Chemistry & Engineering, Issue 9, 2024, Page(s) 2599-2609, ISSN 2058-9883
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4re00270a

Ultrafast diffusion-based unmixing of 1 H NMR spectra

Author(s): Rituraj Mishra, Achille Marchand, Corentin Jacquemmoz, Jean-Nicolas Dumez
Published in: Chemical Communications, Issue 57/19, 2021, Page(s) 2384-2387, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0cc07757g

Ultrafast 2D NMR for the analysis of complex mixtures

Author(s): Célia Lhoste, Benjamin Lorandel, Clément Praud, Achille Marchand, Rituraj Mishra, Arnab Dey, Aurélie Bernard, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Progress in Nuclear Magnetic Resonance Spectroscopy, 2022, ISSN 0079-6565
Publisher: Elsevier BV
DOI: 10.1016/j.pnmrs.2022.01.002

-Frequency-swept pulses for ultrafast spatially encoded NMR

Author(s): Jean-Nicolas Dumez
Published in: Journal of Magnetic Resonance, Issue 323, 2021, Page(s) 106817, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2020.106817

Hyperpolarized ¹³C NMR Metabolomics of Urine Samples at Natural Abundance Applied to Chronic Kidney Disease

Author(s): Victor Ribay, Benoît Charrier, Mikaël Croyal, Bertrand Cariou, Samy Hadjadj, Julien Boccard, Claire Cannet, Jean-Nicolas Dumez, Marine P. M. Letertre, Patrick Giraudeau
Published in: Journal of the American Chemical Society, Issue 147, 2025, Page(s) 644-650, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c12607

Hyperpolarized 13C NMR Spectroscopy of Urine Samples at Natural Abundance by Quantitative Dissolution Dynamic Nuclear Polarization

Author(s): Victor Ribay, Arnab Dey, Benoît Charrier, Clément Praud, Joris Mandral, Jean-Nicolas Dumez, Marine P. M. Letertre, Patrick Giraudeau
Published in: Angewandte Chemie International Edition, 2023, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202302110

Hyperpolarized NMR Metabolomics at Natural 13 C Abundance

Author(s): Arnab Dey, Benoît Charrier, Estelle Martineau, Catherine Deborde, Elodie Gandriau, Annick Moing, Daniel Jacob, Dmitry Eshchenko, Marc Schnell, Roberto Melzi, Dennis Kurzbach, Morgan Ceillier, Quentin Chappuis, Samuel F. Cousin, James G. Kempf, Sami Jannin, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Analytical Chemistry, Issue 92/22, 2020, Page(s) 14867-14871, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c03510?ref=pdf

Fine optimization of a dissolution dynamic nuclear polarization experimental setting for 13C NMR of metabolic samples

Author(s): Arnab Dey, Benoît Charrier, Karine Lemaitre, Victor Ribay, Dmitry Eshchenko, Marc Schnell, Roberto Melzi, Quentin Stern, Samuel F. Cousin, James G. Kempf, Sami Jannin, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Magnetic Resonance, 2022, ISSN 2699-0016
Publisher: Copernicus Publications
DOI: 10.5194/mr-3-183-2022

Quadratic spacing of the effective gradient area for spatially encoded diffusion NMR

Author(s): Rituraj Mishra, Jean-Nicolas Dumez
Published in: Journal of Magnetic Resonance, 2022, Page(s) 107114, ISSN 1090-7807
Publisher: Academic Press
DOI: 10.1016/j.jmr.2021.107114

Online reaction monitoring by single-scan 2D NMR under flow conditions

Author(s): Corentin Jacquemmoz, François Giraud, Jean-Nicolas Dumez
Published in: The Analyst, Issue 145/2, 2020, Page(s) 478-485, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9an01758e

Book chapters (2)

Fast 2D NMR for Metabolomics

Author(s): Clément Praud ; Marine P. M. Letertre ; Arnab Dey ; Jean-Nicolas Dumez ; Patrick Giraudeau
Published in: 2023
Publisher: Royal Society of Chemistry
DOI: 10.1039/bk9781839168062-00377

Fast 2D NMR for Reaction and Process Monitoring

Author(s): M. Bazzoni ; B. Lorandel ; C. Lhoste ; P. Giraudeau ; J.-N. Dumez
Published in: Fast 2D Solution-state NMR: Concepts and Applications, 2023
Publisher: Royal Society of Chemistry
DOI: 10.1039/bk9781839168062-00251