Motif repeats in intrinsically disordered regions of the clathrin mediated endocytosis pathway

Project Information

MultiMotif

Grant agreement ID: 802209

DOI

10.3030/802209

Project closed

EC signature date 12 September 2018

Start date 1 February 2019

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 599 809,00

EU contribution

€ 1 599 809,00

Coordinated by

FORSCHUNGSVERBUND BERLIN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Nuclear magnetic resonance/single molecule fluorescence combinations to study dynamic protein systems

Author(s): Ida Marie Vedel; Andromachi Papagiannoula; Samuel Naudi-Fabra; Sigrid Milles
Published in: Current Opinion in Structural Biology, 2023, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2023.102659

Quantitative Description of Intrinsically Disordered Proteins Using Single-Molecule FRET, NMR, and SAXS.

Author(s): Samuel Naudi-Fabra; Maud Tengo; Malene Ringkjøbing Jensen; Martin Blackledge; Sigrid Milles
Published in: "Journal of the American Chemical Society, American Chemical Society, 2021, 143 (48), pp.20109-20121. ⟨10.1021/jacs.1c06264⟩", Issue 1, 2021, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.1c06264

Synergies of Single Molecule Fluorescence and NMR for the Study of Intrinsically Disordered Proteins

Author(s): Samuel Naudi-Fabra; Martin Blackledge; Sigrid Milles
Published in: "Biomolecules, MDPI, 2021, 12 (1), pp.27. ⟨10.3390/biom12010027⟩", Issue 1, 2021, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom12010027

Promiscuous and multivalent interactions between Eps15 and partner protein Dab2 generate a complex interaction network

Author(s): Andromachi Papagiannoula, Ida Marie Vedel, Kathrin Motzny, Maud Tengo, Arbesa Saiti, Sigrid Milles
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-63090-1

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

Author(s): Brandon T. Malady, Andromachi Papagiannoula, Advika Kamatar, Susovan Sarkar, Gavin T. Lebrun, Liping Wang, Carl C. Hayden, Eileen M. Lafer, David J. Owen, Sigrid Milles, Jeanne C. Stachowiak
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-64816-x

An extended interaction site determines binding between AP180 and AP2 in clathrin mediated endocytosis

Author(s): Samuel Naudi-Fabra, Carlos A. Elena-Real, Ida Marie Vedel, Maud Tengo, Kathrin Motzny, Pin-Lian Jiang, Peter Schmieder, Fan Liu, Sigrid Milles
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-50212-4

Deuterated oxazines are bright near-infrared fluorophores for mitochondrial imaging and single molecule spectroscopy

Author(s): Blaise Gatin-Fraudet, Julius Seifert, Kris Sarach, Christina Holmboe Olesen, Ramona Birke, Sigrid Milles, Melissa Birol, Martin Lehmann, Johannes Broichhagen
Published in: Chemical Communications, Issue 61, 2025, Page(s) 3540-3543, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4cc03807j

Other (3)

Emergence of new function through evolutionary divergence of an intrinsically disordered region

Author(s): Carlos A. Elena-Real, Antonia M. Körber, Blaise Gatin-Fraudet, Alexandra Kovinko, Kathrin Motzny, Arbesa Saiti, Adam Lange, Johannes Broichhagen, Sigrid Milles
Published in: BioRxiv, 2026
Publisher: BioRxiv
DOI: 10.64898/2026.08.25.746950

HaloTag Ligand and HaloTag Protein engineering for a binary fluorescent turn-on probe

Author(s): Blaise Gatin-Fraudet, Ulrich Pabst, Christina H. Olesen, Bianca C. Baciu, Ramona Birke, Sigrid Milles, Johannes Broichhagen
Published in: bioRxiv, 2026
Publisher: openRxiv
DOI: 10.64898/2026.05.15.724826

Biomolecular condensate architecture of an autophagic cargo at molecular resolution in situ

Author(s): Emily Boyle, Sergio Cruz-León, Javier Lizarrondo, Johann Brenner, Hector Mancilla, Jan F. M. Stuke, Jorge Jimenez-Niebla, Sigrid Milles, Sonja Welsch, Carola Hunte, Claudine Kraft, Gerhard Hummer, Florian Wilfling
Published in: bioRxiv, 2026
Publisher: openRxiv
DOI: 10.64898/2026.01.07.698105