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Predicting cardiovascular regeneration: integrating mechanical cues and signaling pathways

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Publications

Mechano-regulated cell-cell signaling in the context of cardiovascular tissue engineering

Author(s): Cansu Karakaya, Jordy G.M. van Asten, Tommaso Ristori, Cecilia M Sahlgren, Sandra Loerakker
Published in: Biomechanics and Modeling in Mechanobiology, 21/1, 2022, Page(s) 5-54, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-021-01521-w

Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls

Author(s): Tommaso Ristori, Oscar M. J. A. Stassen, Cecilia M. Sahlgren, Sandra Loerakker
Published in: International Journal for Numerical Methods in Biomedical Engineering, 36/4, 2020, Page(s) e3323, ISSN 2040-7939
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3323

Computational modeling for cardiovascular tissue engineering: the importance of including cell behavior in growth and remodeling algorithms

Author(s): Sandra Loerakker, Tommaso Ristori
Published in: Current Opinion in Biomedical Engineering, 15, 2020, Page(s) 1-9, ISSN 2468-4511
Publisher: Elsevier
DOI: 10.1016/j.cobme.2019.12.007

Computational modelling to reduce outcome variability in tissue-engineered heart valves

Author(s): Valery L Visser, Polina Zaytseva, Sarah E Motta, Sandra Loerakker, Simon P Hoerstrup, Maximilian Y Emmert
Published in: European Heart Journal, 42/23, 2021, Page(s) 2225-2229, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehab034

Geometry influences inflammatory host cell response and remodeling in tissue-engineered heart valves in-vivo

Author(s): Sarah E. Motta, Emanuela S. Fioretta, Valentina Lintas, Petra E. Dijkman, Monika Hilbe, Laura Frese, Nikola Cesarovic, Sandra Loerakker, Frank P. T. Baaijens, Volkmar Falk, Simon P. Hoerstrup, Maximilian Y. Emmert
Published in: Scientific Reports, 10/1, 2020, Page(s) 19882, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-76322-9

Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity

Author(s): Emanuela S. Fioretta, Sarah E. Motta, Valentina Lintas, Sandra Loerakker, Kevin K. Parker, Frank P. T. Baaijens, Volkmar Falk, Simon P. Hoerstrup, Maximilian Y. Emmert
Published in: Nature Reviews Cardiology, 18/2, 2021, Page(s) 92-116, ISSN 1759-5002
Publisher: Nature Publishing Group
DOI: 10.1038/s41569-020-0422-8