Using Bariatric Surgery to Discover Weight-Loss Independent Mechanisms Leading to the Reversal of Fatty Liver Disease

Project Information

BARINAFLD

Grant agreement ID: 803526

DOI

10.3030/803526

Project closed

EC signature date 31 October 2018

Start date 1 November 2018

End date 31 October 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 354,00

EU contribution

€ 1 499 354,00

Coordinated by

THE HEBREW UNIVERSITY OF JERUSALEM
Israel

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Maternal antagonism of Glp1 reverses the adverse outcomes of sleeve gastrectomy on mouse offspring

Author(s): Liron Hefetz, Rachel Ben-Haroush Schyr, Michael Bergel, Yhara Arad, Doron Kleiman, Hadar Israeli, Itia Samuel, Shira Azulai, Arnon Haran, Yovel Levy, Dana Sender, Amihai Rottenstreich, Danny Ben-Zvi
Published in: JCI Insight, Issue 7, 2023, ISSN 2379-3708
Publisher: JCI
DOI: 10.1172/jci.insight.156424

Sleeve Gastrectomy Is Associated with a Greater Reduction in Plasma Liver Enzymes Than Bypass Surgeries—A Registry-Based Two-Year Follow-Up Analysis

Author(s): Shira Azulai, Ronit Grinbaum, Nahum Beglaibter, Shai Meron Eldar, Moshe Rubin, Rachel Ben-Haroush Schyr, Orly Romano-Zelekha, Danny Ben-Zvi
Published in: Journal of Clinical Medicine, Issue 10/5, 2021, Page(s) 1144, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10051144

Inhibition of somatostatin enhances the long-term metabolic outcomes of sleeve gastrectomy in mice

Author(s): Doron Kleiman, Yhara Arad, Shira Azulai, Aaron Baker, Michael Bergel, Amit Elad, Arnon Haran, Liron Hefetz, Hadar Israeli, Mika Littor, Anna Permyakova, Itia Samuel, Joseph Tam, Rachel Ben-Haroush Schyr, Danny Ben-Zvi
Published in: Molecular Metabolism, Issue 86, 2024, Page(s) 101979, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2024.101979

Differential effects of bariatric surgery and caloric restriction on hepatic one-carbon and fatty acid metabolism

Author(s): Arnon Haran, Michael Bergel, Doron Kleiman, Liron Hefetz, Hadar Israeli, Sarah Weksler-Zangen, Bella Agranovich, Ifat Abramovich, Rachel Ben-Haroush Schyr, Eyal Gottlieb, Danny Ben-Zvi
Published in: iScience, Issue 26, 2024, Page(s) 107046, ISSN 2589-0042
Publisher: Elsevier
DOI: 10.1016/j.isci.2023.107046

Sleeve gastrectomy reveals the plasticity of the human gastric epithelium

Author(s): Amit Elad, Botros Moalem, Dana Sender, Aya Bardugo, Ki-Suk Kim, Yhara Arad, Haya Benhayon, Ayelet Gal Etzyoni, Nehemia Greenstein, Aviv Halfon, Sarah Knapp, Michelle Malis, Bailey Peck, Itia Samuel, Amram Kupietzky, Saleh Daher, Esther Forkosh, David Hakimian, Tiberiu Hershcovici, Nadav Ilani, Lior Katz, Moshe Rottenstreich, Elez Vainer, Yuval Ishay, Eitan Zlotnick, Abed Nasereddin, Idid Shiff, Ar
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-56135-y

Bariatric Surgery Affects Plasma Levels of Alanine Aminotransferase Independent of Weight Loss: A Registry-Based Study

Author(s): Shira Azulai, Ronit Grinbaum, Nahum Beglaibter, Shai Meron Eldar, Moshe Rubin, Shai Carmi, Rachel Ben-Haroush Schyr, Orly Romano-Zelekha, Danny Ben-Zvi
Published in: Journal of Clinical Medicine, Issue 10/12, 2021, Page(s) 2724, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10122724

Sleeve Gastrectomy Suppresses Hepatic Glucose Production and Increases Hepatic Insulin Clearance Independent of Weight Loss

Author(s): Rachel Ben-Haroush Schyr, Abbas Al-Kurd, Botros Moalem, Anna Permyakova, Hadar Israeli, Aya Bardugo, Yhara Arad, Liron Hefetz, Michael Bergel, Arnon Haran, Shahar Azar, Itia Magenheim, Joseph Tam, Ronit Grinbaum, Danny Ben-Zvi
Published in: Diabetes, Issue 70, 2022, Page(s) 2289-2298, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db21-0251