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The Brain Health Toolbox: Facilitating personalized decision-making for effective dementia prevention

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Publications

Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress

Author(s): S Sindi , C Thunborg, A Rosenberg, P Andersen, S Andrieu, L M Broersen, N Coley, C Couderc, C Z Duval, G Faxen-Irving, G Hagman, M Hallikainen, K Håkansson, J Lehtisalo, N Levak, F Mangialasche, J Pantel, E Kekkonen, A Rydström, A Stigsdotter-Neely, A Wimo, T Ngandu, H Soininen, T Hartmann, A Solomon, M Kivipelto
Published in: The Journal of Prevention of Alzheimer's Disease, 2022, ISSN 2426-0266
Publisher: Springer International Publishing AG
DOI: 10.14283/jpad.2022.4

Long‐term dementia risk prediction by the LIBRA score: A 30‐year follow‐up of the CAIDE study

Author(s): Kay Deckers, Mariagnese Barbera, Sebastian Köhler, Tiia Ngandu, Martin Boxtel, Minna Rusanen, Tiina Laatikainen, Frans Verhey, Hilkka Soininen, Miia Kivipelto, Alina Solomon
Published in: International Journal of Geriatric Psychiatry, 35/2, 2019, Page(s) 195-203, ISSN 0885-6230
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/gps.5235

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

Author(s): Ruth Stephen, Yawu Liu, Tiia Ngandu, Riitta Antikainen, Juha Hulkkonen, Juha Koikkalainen, Nina Kemppainen, Jyrki Lötjönen, Esko Levälahti, Riitta Parkkola, Pauliina Pippola, Juha Rinne, Timo Strandberg, Jaakko Tuomilehto, Ritva Vanninen, Miia Kivipelto, Hilkka Soininen, Alina Solomon
Published in: Alzheimer's Research & Therapy, 11/1, 2019, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-019-0506-z

Research diagnostic criteria for Alzheimer’s disease: findings from the LipiDiDiet randomized controlled trial

Author(s): Anna Rosenberg, Alina Solomon, Hilkka Soininen, Pieter Jelle Visser, Kaj Blennow, Tobias Hartmann, Miia Kivipelto
Published in: Alzheimer's Research & Therapy, 13/1, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00799-3

Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus with Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia

Author(s): Timo Pekkala, Anette Hall, Francesca Mangialasche, Nina Kemppainen, Patrizia Mecocci, Tiia Ngandu, Juha O. Rinne, Hilkka Soininen, Jaakko Tuomilehto, Miia Kivipelto, Alina Solomon
Published in: Journal of Alzheimer's Disease, 76/4, 2020, Page(s) 1243-1248, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-200145

36‐month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease

Author(s): Hilkka Soininen, Alina Solomon, Pieter Jelle Visser, Suzanne B Hendrix, Kaj Blennow, Miia Kivipelto, Tobias Hartmann
Published in: Alzheimer's & Dementia, 17/1, 2021, Page(s) 29-40, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12172

Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study

Author(s): Jenni Lehtisalo, Katie Palmer, Francesca Mangialasche, Alina Solomon, Miia Kivipelto, Tiia Ngandu
Published in: Frontiers in Psychiatry, 12, 2021, ISSN 1664-0640
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2021.624125

Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS

Author(s): Rosenberg A, Mangialasche F, Ngandu T, Solomon A, Kivipelto M
Published in: The Journal of Prevention of Alzheimer's Disease, 2019, ISSN 2426-0266
Publisher: Springer International Publishing AG
DOI: 10.14283/jpad.2019.41

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial

Author(s): Anna Sandebring-Matton, Julen Goikolea, Ingemar Björkhem, Laura Paternain, Nina Kemppainen, Tiina Laatikainen, Tiia Ngandu, Juha Rinne, Hilkka Soininen, Angel Cedazo-Minguez, Alina Solomon, Miia Kivipelto
Published in: Alzheimer's Research & Therapy, 13/1, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00790-y

World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Author(s): Miia Kivipelto, Francesca Mangialasche, Heather M. Snyder, Ricardo Allegri, Sandrine Andrieu, Hidenori Arai, Laura Baker, Sylvie Belleville, Henry Brodaty, Sonia M. Brucki, Ismael Calandri, Paulo Caramelli, Christopher Chen, Howard Chertkow, Effie Chew, Seong H. Choi, Neerja Chowdhary, Lucía Crivelli, Rafael De La Torre, Yifeng Du, Tarun Dua, Mark Espeland, Howard H. Feldman, Maris Hartmanis, Tob
Published in: Alzheimer's & Dementia, 16/7, 2020, Page(s) 1078-1094, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12123

White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial

Author(s): Stephen R, Solomon A, Ngandu T, Levälahti E, Rinne JO, Kemppainen N, Parkkola R, Antikainen R, Strandberg T, Kivipelto M, Soininen H, Liu Y; FINGER study group
Published in: Journal of Alzheimer's Disease, 2020, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-200423

The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People

Author(s): Jenni Kulmala, Tiia Ngandu, Satu Havulinna, Esko Levälahti, Jenni Lehtisalo, Alina Solomon, Riitta Antikainen, Tiina Laatikainen, Pauliina Pippola, Markku Peltonen, Rainer Rauramaa, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto
Published in: Journal of the American Geriatrics Society, 67/6, 2019, Page(s) 1138-1144, ISSN 0002-8614
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jgs.15837

Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions

Author(s): Ruth Stephen, Mariagnese Barbera, Ruth Peters, Nicole Ee, Lidan Zheng, Jenni Lehtisalo, Jenni Kulmala, Krister Håkansson, Neerja Chowdhary, Tarun Dua, Alina Solomon, Kaarin J Anstey, Miia Kivipelto
Published in: Frontiers in Neurology, 2021, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2021.763573

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline

Author(s): Timo Pekkala, Anette Hall, Tiia Ngandu, Mark van Gils, Seppo Helisalmi, Tuomo Hänninen, Nina Kemppainen, Yawu Liu, Jyrki Lötjönen, Teemu Paajanen, Juha O. Rinne, Hilkka Soininen, Miia Kivipelto, Alina Solomon
Published in: Frontiers in Aging Neuroscience, 12, 2020, ISSN 1663-4365
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnagi.2020.00228

Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial

Author(s): Elisa Neuvonen, Jenni Lehtisalo, Alina Solomon, Riitta Antikainen, Satu Havulinna, Tuomo Hänninen, Tiina Laatikainen, Jaana Lindström, Nina Rautio, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto & Tiia Ngandu
Published in: Aging Clinical and Experimental Research, 2022, ISSN 1720-8319
Publisher: Springer Nature Switzerland AG
DOI: 10.1007/s40520-022-02088-x

Late‐life personality traits, cognitive impairment, and mortality in a population‐based cohort

Author(s): Elisa Neuvonen, Anette Hall, Anna‐Maija Tolppanen, Tiia Ngandu, Minna Rusanen, Tiina Laatikainen, Hilkka Soininen, Miia Kivipelto, Alina Solomon
Published in: International Journal of Geriatric Psychiatry, 35/9, 2020, Page(s) 989-999, ISSN 0885-6230
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/gps.5321

The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER).

Author(s): Tiia Ngandu; Tiia Ngandu; Jenni Lehtisalo; Jenni Lehtisalo; Saana Korkki; Saana Korkki; Alina Solomon; Alina Solomon; Alina Solomon; Nicola Coley; Riitta Antikainen; Riitta Antikainen; Lars Bäckman; Tuomo Hänninen; Jaana Lindström; Tiina Laatikainen; Tiina Laatikainen; Teemu Paajanen; Satu Havulinna; Markku Peltonen; Markku Peltonen; Anna Stigsdotter Neely; Anna Stigsdotter Neely; Timo E. Stran
Published in: Alzheimer's and Dementia, 5, 2021, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12492

Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines

Author(s): Kaarin J Anstey, Lidan Zheng, Ruth Peters , Scherazad Kootar, Mariagnese Barbera, Ruth Stephen, Tarun Dua, Neerja Chowdhary, Alina Solomon, Miia Kivipelto
Published in: Frontiers in Neurology, 2022, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2021.765454

Occupational complexity and cognition in the FINGER multidomain intervention trial

Author(s): Anders Rydström, Alexander Darin-Mattsson, Ingemar Kåreholt, Tiia Ngandu, Jenni Lehtisalo, Alina Solomon, Riitta Antikainen, Lars Bäckman, Tuomo Hänninen, Tiina Laatikainen, Esko Levälahti, Jaana Lindström, Teemu Paajanen, Satu Havulinna, Markku Peltonen, Shireen Sindi, Hilkka Soininen, Anna Stigsdotter Neely, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto, Francesca Mangialasche
Published in: Alzheimer's and dementia, 2022, ISSN 1552-5279
Publisher: John Wiley & Sons, Inc.
DOI: 10.1002/alz.12561

Telomere Length Change in a Multidomain Lifestyle Intervention to Prevent Cognitive Decline: A Randomized Clinical Trial

Author(s): Shireen Sindi, Alina Solomon, Ingemar Kåreholt, Iiris Hovatta, Riitta Antikainen, Tuomo Hänninen, Esko Levälahti, Tiina Laatikainen, Jenni Lehtisalo, Jaana Lindström, Teemu Paajanen, Markku Peltonen, Dharma Singh Khalsa, Benjamin Wolozin, Timo Strandberg, Jaakko Tuomilehto, Hilkka Soininen, Tiia Ngandu, Miia Kivipelto
Published in: The Journals of Gerontology: Series A, 76/3, 2020, Page(s) 491-498, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glaa279

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index

Author(s): Kay Deckers, Sebastian Köhler, Tiia Ngandu, Riitta Antikainen, Tiina Laatikainen, Hilkka Soininen, Timo Strandberg, Frans Verhey, Miia Kivipelto, Alina Solomon
Published in: Alzheimer's & Dementia, 17/7, 2021, Page(s) 1205-1212, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12281

Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk

Author(s): Alina Solomon, Ron Handels, Anders Wimo, Riitta Antikainen, Tiina Laatikainen, Esko Levälahti, Markku Peltonen, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto, Tiia Ngandu
Published in: Journal of Alzheimer's Disease, 2021, Page(s) 1-6, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-210331

Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial

Author(s): Elisa Neuvonen, Jenni Lehtisalo, Tiia Ngandu, Esko Levälahti, Riitta Antikainen, Tuomo Hänninen, Tiina Laatikainen , Jaana Lindström, Teemu Paajanen, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto, Alina Solomon
Published in: JOURNAL OF CLINICAL MEDICINE, 2022, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11051449

Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial

Author(s): Jenni Lehtisalo, Minna Rusanen, Alina Solomon, Riitta Antikainen, Tiina Laatikainen, Markku Peltonen, Timo Strandberg, Jaakko Tuomilehto, Hilkka Soininen, Miia Kivipelto, Tiia Ngandu
Published in: European Heart Journal, 2022, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehab922

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services—part 4 of 6

Author(s): Alina Solomon, Ruth Stephen, Daniele Altomare, Emmanuel Carrera, Giovanni B. Frisoni, Jenni Kulmala, José Luis Molinuevo, Peter Nilsson, Tiia Ngandu, Federica Ribaldi, Bruno Vellas, Philip Scheltens & Miia Kivipelto on behalf of the European Task Force for Brain Health Services
Published in: Alzheimer's Research & Therapy, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00875-8

Progression to dementia in memory clinic patients with mild cognitive impairment and normal β-amyloid

Author(s): Anna Rosenberg, Alina Solomon, Vesna Jelic, Göran Hagman, Nenad Bogdanovic, Miia Kivipelto
Published in: Alzheimer's Research & Therapy, 11/1, 2019, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-019-0557-1

Change in CAIDE Dementia Risk Score and Neuroimaging Biomarkers During a 2-Year Multidomain Lifestyle Randomized Controlled Trial: Results of a Post-Hoc Subgroup Analysis

Author(s): Ruth Stephen, Tiia Ngandu, Yawu Liu, Markku Peltonen, Riitta Antikainen, Nina Kemppainen, Tiina Laatikainen, Jyrki Lötjönen, Juha Rinne, Timo Strandberg, Jaakko Tuomilehto, Ritva Vanninen, Hilkka Soininen, Miia Kivipelto, Alina Solomon
Published in: The Journals of Gerontology: Series A, 76/8, 2021, Page(s) 1407-1414, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glab130

Multimodal Prediction of Dementia and Brain Pathology

Author(s): Timo Pekkala (PhD thesis, main supervisor Alina Solomon)
Published in: 2020, ISBN 978-952-61-3380-5
Publisher: Publications of the University of Eastern Finland. Dissertations in Health Sciences, no 563

Dementia prevention in at-risk individuals: Focus on selection and engagement of target populations

Author(s): Anna Rosenberg (PhD thesis, co-supervisor Alina Solomon)
Published in: 2020, ISBN 978-952-61-3582-3
Publisher: Publications of the University of Eastern Finland. Dissertations in Health Sciences, no 588

The Finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): Findings from the structural brain MRI sub-study

Author(s): Ruth Stephen (PhD thesis, main supervisor Alina Solomon)
Published in: 2020, ISBN 978-952-61-3424-6
Publisher: Publications of the University of Eastern Finland. Dissertations in Health Sciences, no 572