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Exploring the link between innate Immunity and cellular Aging

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Interplay of cGAS with chromatin (opens in new window)

Author(s): Marilena Wischnewski, Andrea Ablasser
Published in: Elsevier, 2021, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2021.05.011

Structural mechanism of cGAS inhibition by the nucleosome (opens in new window)

Author(s): Ganesh R. Pathare, Alexiane Decout, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Melenec, Beat Fierz, Nicolas H. Thomä, Andrea Ablasser
Published in: Nature, 2020, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2750-6

The cGAS–STING pathway as a therapeutic target in inflammatory diseases (opens in new window)

Author(s): Decout, Alexiane; Katz, Jason D.; Venkatraman, Shankar; Ablasser, Andrea
Published in: Nature Reviews Immunology, 2021, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-021-00524-z

Clathrin-associated AP-1 controls termination of STING signalling (opens in new window)

Author(s): Ying Liu, Pengbiao Xu, Sophie Rivara, Chong Liu, Jonathan Ricci, Xuefeng Ren, James H. Hurley, Andrea Ablasser.
Published in: Nature, 2022, ISSN 1476-4687
Publisher: Spring Nature Group
DOI: 10.1038/s41586-022-05354-0

BAF restricts cGAS on nuclear DNA to prevent innate immune activation (opens in new window)

Author(s): Baptiste Guey, Marilena Wischnewski, Alexiane Decout, Kristina Makasheva, Murat Kaynak, Mahmut S. Sakar, Beat Fierz, Andrea Ablasser
Published in: Science, Issue 369/6505, 2020, Page(s) 823-828, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaw6421

cGAS–STING drives ageing-related inflammation and neurodegeneration (opens in new window)

Author(s): Muhammet F. Gulen, Natasha Samson, Alexander Keller, Marius Schwabenland, Chong Liu, Sélène Glück, Vivek V. Thacker, Lucie Favre, Bastien Mangeat, Lona Kroese, Paul Krimpenfort, Marco Prinz, Andrea Ablasser.
Published in: Nature, 2023, ISSN 1476-4687
Publisher: Springer Nature Group
DOI: 10.1038/s41586-023-06373-1

The cGAS-STING pathway drives type I IFN immunopathology in COVID-19 (opens in new window)

Author(s): Di Domizio, J., Gulen, M.F., Saidoune, F. et al.
Published in: Nature, 2022, ISSN 1476-4687
Publisher: Springer Nature
DOI: 10.1038/s41586-022-04421-w

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