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Exploring the link between innate Immunity and cellular Aging

Project description

DNA: common culprit of ageing and immunity?

Inflammation is our immune system’s response to harmful stimuli such as pathogens or injury. One of the key mediators of inflammation is DNA, which triggers the cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) pathway of innate immunity. The EU-funded ImAgine project is interested to understand the mechanisms by which cells detect and react to DNA, inducing inflammatory processes. Researchers aim to identify key players in the process and develop novel anti-inflammatory medicines. They are working under the hypothesis that inflammation constitutes one of the hallmarks of ageing and age-related disorders, which could be treated by targeting the inflammatory process.

Host institution

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Net EU contribution
€ 1 489 520,00
Address
Batiment Ce 3316 Station 1
1015 Lausanne
Switzerland

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 489 520,00

Beneficiaries (1)

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
Net EU contribution
€ 1 489 520,00
Address
Batiment Ce 3316 Station 1
1015 Lausanne

See on map

Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 489 520,00