Paternal Epigenetic Inheritance: A man’s life experiences may impact health of his unborn children and grandchildren

Project Information

PATER

Grant agreement ID: 805057

DOI

10.3030/805057

Project closed

EC signature date 12 December 2018

Start date 1 January 2019

End date 30 June 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

STOCKHOLMS UNIVERSITET
Sweden

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice

Author(s): Radwa Almamoun, Paula Pierozan, Lokeshwaran Manoharan, Oskar Karlsson
Published in: Ecotoxicology and Environmental Safety, Issue 262, 2024, Page(s) 115321, ISSN 0147-6513
Publisher: Academic Press
DOI: 10.1016/j.ecoenv.2023.115321

Mechanistic screening of reproductive toxicity in a novel 3D testicular co-culture model shows significant impairments following exposure to low-dibutyl phthalate concentrations

Author(s): Radwa Almamoun, Paula Pierozan, Oskar Karlsson
Published in: Archives of Toxicology, Issue 98, 2024, Page(s) 2695-2709, ISSN 0340-5761
Publisher: Springer Verlag
DOI: 10.1007/s00204-024-03767-6

Male-transmitted transgenerational effects of the herbicide linuron on DNA methylation profiles in Xenopus tropicalis brain and testis

Author(s): Mauricio Roza, Andreas N.M. Eriksson, Sofie Svanholm, Cecilia Berg, Oskar Karlsson
Published in: Science of The Total Environment, Issue 923, 2024, Page(s) 170949, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2024.170949

Pesticide-induced multigenerational effects on amphibian reproduction and metabolism

Author(s): Oskar Karlsson, Sofie Svanholm, Andreas Eriksson, Joseph Chidiac, Johanna Eriksson, Fredrik Jernerén, Cecilia Berg
Published in: Science of The Total Environment, Issue 775, 2022, Page(s) 145771, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2021.145771

Chemical safety and the exposome

Author(s): Oskar Karlsson
Published in: Emerging Contaminants, Issue 9, 2023, Page(s) 100225, ISSN 2405-6650
Publisher: Elsevier BV
DOI: 10.1016/j.emcon.2023.100225

Persistent effects of di-n-butyl phthalate on liver transcriptome: Impaired energy and lipid metabolic pathways

Author(s): Eleftheria Theodoropoulou, Paula Pierozan, Francesco Marabita, Andrey Höglund, Oskar Karlsson
Published in: Chemosphere, Issue 368, 2025, Page(s) 143605, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2024.143605

Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice

Author(s): Paula Pierozan, Liselott Källsten, Eleftheria Theodoropoulou, Radwa Almamoun, Oskar Karlsson
Published in: Science of The Total Environment, Issue 878, 2024, Page(s) 162741, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162741

Adult Exposure to Di-N-Butyl Phthalate (DBP) Induces Persistent Effects on Testicular Cell Markers and Testosterone Biosynthesis in Mice

Author(s): Liselott Källsten, Radwa Almamoun, Paula Pierozan, Erik Nylander, Kalliroi Sdougkou, Jonathan W. Martin, Oskar Karlsson
Published in: International Journal of Molecular Sciences, Issue 23, 2024, Page(s) 8718, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23158718

Pesticide-induced transgenerational alterations of genome-wide DNA methylation patterns in the pancreas of Xenopus tropicalis correlate with metabolic phenotypes

Author(s): Mauricio Roza, Andreas N.M. Eriksson, Sofie Svanholm, Cecilia Berg, Oskar Karlsson
Published in: Journal of Hazardous Materials, Issue 478, 2025, Page(s) 135455, ISSN 0304-3894
Publisher: Elsevier BV
DOI: 10.1016/j.jhazmat.2024.135455

Di-n-Butyl Phthalate and Its Monoester Metabolite Impairs Steroid Hormone Biosynthesis in Human Cells: Mechanistic In Vitro Studies

Author(s): Liselott Källsten, Paula Pierozan, Jonathan W. Martin, Oskar Karlsson
Published in: Cells, Issue 11, 2024, Page(s) 3029, ISSN 2073-4409
Publisher: MDPI AG
DOI: 10.3390/cells11193029

Pesticide-induced multigenerational effects on amphibian reproduction and metabolism

Author(s): Oskar Karlsson, Sofie Svanholm, Andreas Eriksson, Joseph Chidiac, Johanna Eriksson, Fredrik Jernerén, Cecilia Berg
Published in: Science of The Total Environment, Issue 775, 2021, Page(s) 145771, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2021.145771

Thesis and dissertations (2)

Toxicogenomic effects of pesticides : Epigenetic and transgenerational consequences of developmental pesticide exposure in Xenopus tropicalis

Author(s): Roza, Mauricio
Published in: PhD Thesis Stockholm University, Issue 1, 2025
Publisher: Stockholm University

In vitro and in vivo studies on the toxicology of di-n-butyl phthalate (DBP) : Effects on reproductive, endocrine, and immune systems

Author(s): Källsten, Liselott
Published in: PhD Thesis Stockholm University, Issue 1, 2022
Publisher: Stockholm University