Nexilis augmentation system

Objective

Demographic changes in western countries are significantly increasing osteoporosis and therefore, the incidence of poor bone quality. Osteoporosis affects an estimated 75 million people in Europe, US and Japan and it has been estimated the number of osteoporotic fractures at 9 million per year whose treatment cost are currently reaching €31.7 billion (€76.7 billion in 2050) for Europe and €45.5 billion (€181.8 billion in 2050) for the US. Osteoporosis complicates the treatment of these fractures dramatically, because implants developed for good bone quality tend to fail in osteoporotic bone.
The patented NEXILIS augmentation system (NAS) overcomes these challenges by applying an implantable polymeric sleeve around the original implant. By using ultrasonic energy, the polymeric sleeve is molded into the pores of the host bone forming a strong and uniform bond with the adjacent bone. The original device will be implanted in the created denser bony environment leading to enhanced immediate stability. Therefore, NAS technology will significantly improve the treatment of osteoporotic bone fractures.
Initially, we aim to tackle pedicle screws in spinal surgery market due to its largely unmet medical needs and large market size (around 1 €billion) in Europe by 2020 and in the US by 2022. Nevertheless, our plan is to widespread the use of NAS technology in further market applications like maxillofacial surgery, sports medicine, trauma surgery, or orthopedic applications opening a wide range of business opportunities.

Fields of science

• medical and health sciences › clinical medicine › surgery
• natural sciences › chemical sciences › polymer sciences
• medical and health sciences › medical biotechnology › implants

Programme(s)

• H2020-EU.2.1.2. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies Main Programme
• H2020-EU.2.1.5. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing
• H2020-EU.2.1.3. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials
• H2020-EU.2.3.1. - Mainstreaming SME support, especially through a dedicated instrument

Topic(s)

• SMEInst-02-2016-2017 - Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs

Call for proposal

H2020-SMEInst-2016-2017

See other projects for this call

Sub call

H2020-SMEINST-1-2016-2017

Funding Scheme

SME-1 - SME instrument phase 1

Coordinator

NEXILIS AG

Net EU contribution

€ 50 000,00

Address

Dammstrasse 14
2540 Grenchen
Switzerland

Region

Schweiz/Suisse/Svizzera › Espace Mittelland › Solothurn

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Links

Non-EU contribution

€ 21 429,00